查询词典 antagonist

BACKGROUND: Alginic sodium diester possesses neuroprotective function because of its selective calcium antagonist effects.

背景：藻酸双酯钠具有选择性钙拮抗作用，从而产生神经保护作用。

Methods Synthesize integrin αvβ3 antagonist chemically and conjugate to chlorambucil through a amido bond.

目的 合成整合素αvβ3拮抗剂－苯丁酸氮芥偶联毒素，并检测其体外抗肿瘤活性。

The results obtained are as follows:(1) intrarenal artery injection of capsaicin (20, 40, and 60 nmol/kg) increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with ruthenium red (40 mmol/kg), a capsaicin receptor antagonist, completely abolished the effect of capsaicin; and (3) pretreatment with a nitric oxide synthase inhibitor L-NAME ( N6-nitro-L-arginine methylester, 0.1 mmol/kg), significantly enhanced the ARNA response to capsaicin.

结果表明：(1)肾动脉内注射辣椒素20、40和60nmol/kg可呈剂量依赖性地兴奋肾传入纤维的活动，而动脉血压不变；(2)静脉内预先应用辣椒素受体阻断剂钌红(40 mmok/kg)，可完全阻断辣椒素对肾传入纤维的兴奋作用。(3)静脉内预先注射一氧化氮合酶抑制剂L-NAME(0.1 mmok/kg)，能延长并增强肾传入神经对辣椒素的反应。

The results obtained are as follows:(1) injection of 50, 100, and 200 nmol/kg adenosine into the renal artery increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with 8-cyclopenthl -1,3-dipropylxanthine (DPCPX, 160 nmol/kg), an adenosine A1 receptor antagonist, partly abolished the effect of adenosine; and (3) pretreatment with a nitric oxide synthase inhibitor N w-nitro- L -arginine methylester (L -NAME, 0.1 mmol/kg) significantly enhanced the ARNA response to adenosine.

结果表明：(1)肾动脉内注射50， 100和200 nmol/kg腺苷可呈剂量依赖性地兴奋肾神经传入纤维的活动，而动脉血压不变。(2)肾动脉内预先应用选择性腺苷A1受体阻断剂DPCPX (160 nmol/kg)，可部分阻断腺苷对肾神经传入纤维的兴奋作用。(3)静脉应用一氧化氮合酶抑制剂 L -NAME(0.1 mmol/kg)预处理，延长并增强了肾神经传入纤维对腺苷的反应。

The results obtained are as follows:(1) injection of 50, 100, and 200 nmol/kg adenosine into the renal artery increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2)pretreatment with 8-cyclopenthl-1,3-dipropylxanthine (DPCPX, 160 nmo//kg), an adenosine A1 receptor antagonist, partly abolished the effect of adenosine; and (3) pretreatment with a nitric oxide synthase inhibitor Nω-nitro-L-arginine methylester (L-NAME, 0.1 mmol/kg)significantly enhanced the ARNA response to adenosine.

结果表明：(1)肾动脉内注射50，100和200nmol/kg腺苷可呈剂量依赖性地兴奋肾神经传入纤维的活动，而动脉血压不变。(2)肾动脉内预先应用选择性腺苷A1受体阻断剂DPCPX(160nmol/kg)，可部分阻断腺苷对肾神经传入纤维的兴奋作用。(3)静脉应用一氧化氮合酶抑制剂L-NAME(0.1mmol/kg)预处理，延长并增强了肾神经传入纤维对腺苷的反应。

The increased ARNA produced by intrapelvic infusion of DADLE was unaffected by pretreatment of rats with the NK-1 receptor antagonist, spantide I (0.1mg/ml, 20μl/min).

另外也发现，由肾盂灌注类鸦片拮抗剂，并不会改变因肾盂内压力增加而活化的肾压力性受体时ARNA的增加；而灌注DADLE也不会改变因肾盂灌注高张食盐水(600mM NaCl)而活化肾化学性受体时ARNA的增加。

Objective: To determine the inhibitory effects of BIO-1211, a very late antigen-4 (vla-4) antagonist, on bronchoconstriction and neutrophil adhesion in rats.

目的：研究迟缓抗原－4(very late antigen-4， VLA-4)拮抗剂BIO-1211对大鼠支气管收缩和白细胞黏附反应的影响。

Finally, we found that MK801, a complete antagonist of NMDA receptor, abolished increasing cell surface expression of NMDA receptor afforded by carnosine or clobenpropit.

最后我们还发现NMDA受体完全阻断剂MK801能阻断肌肽和clobenpropit引起的NMDA受体膜上表达增加。

Based on all above, Cd2+、Pb2+ single and their combined pollution led to some damage effects on seed germination of Casuarina equisetifolia. The results also suggest there is a cooperative effect of Cd2+and Pb2+ on seed germination,but there is an antagonist effect on membrane lipid oxidation and antioxidants physiological characteristics in a way.

研究表明，Cd2+、Pb2+单一及复合污染都会对木麻黄的初期生长造成伤害，Cd2+、Pb2+胁迫在木麻黄种子萌发生长上表现出协同效应，在对生物体膜脂过氧化及抗氧化生理反应上存在一定程度的拮抗作用。

Objective To study the protective effect and mechanism of endothelin-1(ET-1)-re- ceptor antagonist PD142893 on early ischemia-reperfusion injury in rats lung allografts.

肺缺血再灌注损伤是肺移植术后早期死亡的主要原因，寻找有效方法预防和减轻肺IRI，有着重要的临床意义〔'一3〕。

I'm going tor her!

我这就去救她！

As rise are design to help keep a several toney , a brain chemical at continues lever.

SSRI被设计来帮助保持血液中的复合胺即在大脑中一个连续水平的化学物质。