查询词典 angiotensin

The main process: angiotensinogen is the perform of angiotensin and transformed into angiotensin I by the rennin.

可能在高血压及PIH发病过程中起一定作用。PIH有较强的遗传倾向，基因变异可能是PIH发病的重要因素之一。

Objective: Rennin angiotensin aldosterone system plays a crucial role in the initiation and development of cardiac remodeling. Angiotensin II has multiple physiological effects on the cardiovascular system.

目的：肾素-血管紧张素-醛固酮系统过度活跃在多种心血管疾病的发生、发展中发挥重要作用，血管紧张素Ⅱ作为重要的生长促进因子，对多种组织、细胞的生长具有促进作用，是刺激心肌肥厚的主要因素之一。

ACE inhibitors work by inhibiting the conversion of angiotensin I to the potent vasoconstrictor, angiotensin II, thereby improving blood flow and blood pressure.

有报告显示，欧盟每年的经济大约有1690亿欧元被投入到对高血压的治疗中。

This enzyme catalyses the conversion of angiotensin I to angiotensin II in the blood plasma and endothelia and prevents the breakdown of bradykinin.

这种酶催化的血管紧张素一血管紧张素血液中的血浆和内皮二，防止故障的激肽转换。

Methods; In APS treatment group and control group, levels of insulin, C-peptide, myocardial enzymes, glycosylated serum protein and angiotensin were measured; Expression levels of chymase and angiotensin-coverting enzyme mRNA were detected by RT-PCR.

检测APS治疗组和对照组DM仓鼠的胰岛素、C肽、心肌酶谱、糖化血清蛋白和血浆。

Methods In APS group and diabetes mellitus control group, levels of serum glucose, insulin, C peptide, myocardial enzymes, glycosylated serum protein and angiotensin Ⅱ in plasma and myocardial were tested; Immuno-histochemistry was used to measure expression levels of type Ⅰ and type Ⅲ collagen; Expression levels of chymase Mrna and angiotensin-converting enzyme mRNA were detected by using fluorescent quantitative polymerize-chain-reaction; Activities of chymase and ACE were tested by radioimmunoassay.

检测APS治疗组和DM对照组仓鼠的血糖、胰岛素、C肽、心肌酶谱、糖化血清蛋白水平，血浆和心肌组织的AngⅡ含量；免疫组化法检测心肌Ⅰ、Ⅲ型胶原；荧光定量PCR法检测心肌chymase和ACE mRNA表达；放免法检测chymase和ACE活性。

Results: It was found that the myocardial chymase-like activity increased markedly in hypertrophied rat (2,6,12 weeks);the angiotensinⅡand aldosterone contents increased significantly in hypertrophied rat (12 weeks);and the myocardium angiotensin Ⅱ,aldosterone levels correlated positively to the myocardium chymase- like activity .

结果：术后2、6、12周心肌肥厚组大鼠心肌组织糜酶样活性较同期正常对照组显著增高（P＜0.01）；术后12 周心肌肥厚组大鼠心肌血管紧张素Ⅱ、醛固酮含量较同期正常对照组明显增加（P＜0.01）；心肌组织血管紧张素Ⅱ、醛固酮水平与糜酶样活性呈正相关（P＜0.05）。

Fie years after initiation of treatment, 79% patients were still on renin-angiotensin inhibitors, 65% on -blockers, 56% on spironolactone, and 83% on statins. Notably, multiple drug treatment and increased seerity of heart failure was associated with persistence of treatment. Nonpersistence with renin-angiotensin inhibitors,-blockers, and statins was associated with increased mortality with hazard ratios for death of 1.37 (95% CI, 1.31 to 1.42), 1.25 (95% CI, 1.19 to 1.32), 1.88 (95% CI, 1.67 to 2.12), respectiely.

开始治疗5年后，有79％病人继续使用肾素血管紧张素抑制剂，65％用阻滞剂，56％用安体舒通，83％使用他汀类，值得注意的是，联合用药和心衰的加重同坚持治疗相关，无法坚持使用肾素血管紧张素抑制剂，阻滞剂，安体舒通，他汀类药物的病人同增加的死亡率相关，其死亡危险比分别为1.37 (95%可信区间， 1.31 － 1.42)， 1.25 (95%可信区间， 1.19 － 1.32)， 1.88 (95%可信区间， 1.67 － 2.12)，。

Cardiac hypertrophy and extracellular matrix remodeling happened as a result of chronic overrange of pressure in heart and hypervolaemia which lead to damage of relaxation and compliance of heart.Drugs including renin-angiotensin converting enzyme inhibitor,angiotensin receptor blocker,aderergic receptor blocker,aldrosteron antagonism,tatins endothelin receptor blocker pancreatic kiniogenase and calcalium channel blocker,can delay or reverse the remodeling by several mechanisms.

主要表现为心脏在慢性超负荷的压力、容量作用下发生的病理改变致使左室肥厚组织胶原结构发生改变，导致心肌顺应性降低，舒张功能受到损害；作用于肾素-血管紧张素系统的药物及肾上腺素受体阻滞剂、醛固酮拮抗剂、他汀类药物、内皮素受体拮抗剂、胰激肽原酶、钙通道阻滞剂等药物通过不同途径和机制延缓和逆转左心室重构。

Importantly, activation of the renin-angiotensin system was noted in the triply n/i/eNOS-/- mice, and long-term oral treatment with an angiotensin II type 1 receptor blocker significantly suppressed coronary arteriosclerotic lesion formation and the occurrence of spontaneous myocardial infarction and improved the prognosis of those mice, along with ameliorating the metabolic abnormalities.

重要的一点是我们注重到三重缺陷小鼠的肾素-血管紧张素系统激活，而长期口服血管紧张素II 1型受体阻滞剂可以显著抑制冠状动脉硬化损伤的形成以及自发性心肌梗死的发生，并改善这些小鼠的预后，同时也能改善代谢异常情况。

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。