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So it can be essential momitoringindex of colon carcinoma and its tumor specificness is apply by manygene therapy of tumor. Transcriptional regulatory element of CEAcontains enhancer element and promotor in the 5th flanking region whichcan control expression of objective gene in positive cancer tissue of CEA. Objectives: To explore the joint promoter with high activity,consisting CEA promotor and CMV enhanser.

目的：本课题探讨由CEA启动子、CMV增强子组成的高活性嵌合启动子，通过融合启动子的调控提高融合自杀基因yCDglyTK在靶细胞表达的特异性；并以无毒副作用生物相容性好的磷酸钙纳米为载体，将该自杀基因靶向导入结肠癌细胞中，以达到提高基因治疗靶向性及安全性的目的。

In this paper, arrangement scheme of a novel multi-star phase shifted pole changing coil was given and the methods to determine coil split ratio were analyzed. According to electromagnetic theory, 2D electromagnetic mathematical model in which stator windings were spitted coil was developed, and magnetic field distribution of the novel motor at starting was solved by finite element method, starting performance of motor was calculated. Based on energy method, rotor slot leakage reactance under different poles and different loads were calculated, and the variation of rotor slot leakage reactance with loads was gotten. Based on time-step finite element method, distribution of branch current in stator windings and operating performance were calculated and analyzed when branch was unbalance, the method to calculate circulating loss in stator windings of novel multi-star phase shifted pole changing motor was given, and the effects of the loads variation and degree of unequilibrium on circulating loss in stator windings were calculated and analyzed.

论文系统的给出了采用分裂线圈法新型多星形移相变极绕组的排列方案，进一步分析线圈分裂比的确定方法；根据电磁场理论，建立了定子为分裂线圈绕组的电机二维电磁场数学模型，并采用场路耦合法求解了新型多星形移相变极电机起动时的磁场分布，计算了电机起动性能和基于能量法计算了不同极数下起动时转子槽漏抗和不同负载时转子槽漏抗，得出转子槽漏抗随负载变化的规律；采用时步有限元法计算分析了定子绕组支路不平衡时支路电流的分布情况及运行性能，给出了新型多星形移相变极电机定子绕组环流损耗的计算方法，分析比较了负载的变化和支路不平衡度大小对定子绕组环流损耗的影响。

Based on the laser longitudinal mode splitting theory, a novel scheme of dual-frequency laser with large frequency-difference is presented using electrically controlled birefringence of liquid crystal, and the transmitted resonant mode splitting by birefringent of Fabry-Perot etalon has been analyzed theoretically. A new element of liquid crystal Fabry-Perot etalon is designed and fabricated, which serves as aselector and splitter of both laser longitudinal modes and Fabry-Perot etalons transmitted resonant modes. Two different experimental systems of laser-diode end-pumped Nd:YAG laser have been set up using two different LDs, and the transmission of liquid-crystal cell have been measured. When the empty LCFP is inserted in the cavity of high-power LD pumped Nd:YAG laser, the oscillation of a single laser longitudinal mode have been observed, such a result shows that the designed and fabricated LCFP element is capable of selecting single axial mode. While an anti-reflected liquid crystal cell is inserted in the cavity of Nd:YAG laser end-pumped by the high-power LD, it is difficult to confirm weather the laser longitudinal modes have been spitted or not. The subject is summarized in this thesis and the improvement of the project has been presented.

论文以激光纵模的分裂理论为基础，提出了可望获得几十GHz甚至上百GHz的液晶电控双折射双频Nd：YAG激光器的总体方案，并对用双折射效应分裂F-P标准具透射谐振模进行了理论分析；设计并加工了一种集激光纵模选择、激光纵模分裂和F-P标准具谐振透射模分裂于一体的多功能元件——液晶电控双折射F-P标准具；建立了两种不同功率激光二极管端面泵浦的Nd：YAG激光实验系统，并对液晶盒的透射性质进行了测试；将未灌注液晶的空液晶F-P摘要标准具插入大功率LD泵浦Nd：、叭G激光谐振腔内，观察到了单纵模激光输出，说明所设计和加工的液晶F一P标准具具有纵模选择能力；将镀有增透膜的液晶盒插入大功率LD泵浦Nd八7AG激光谐振腔内，是否产生了激光纵模分裂现象还难以确定。

In this paper, a procedure of nonlinear analysis of the cable-stayed bridge was developed based on the nonlinear theory of structures using the finite element method, in which the vehicle-bridge interaction element based on the concept of dynamic condensation is used. The influence of vehicles on the response of the cable-stayed bridge is studied by employing the spung mass model and the bridge model with and without considering cable vibration modes.

本文拟应用非线性力学分析程序与有限元素数值计算法，建立斜张桥的非线性分析程序，应用VBI的车桥互制元素配合动态浓缩的观念，以悬浮移动质量模拟车体对斜张桥的影响，并对考虑与不考虑缆索振动模态两种分析模型，做一对应分析比较。

This study performed the three-dimensional nonlinear finite element analyses using a general purpose finite element program ABAQUS to simulate the structural behaviors of two full-scale H-beam to box-column subassemblage specimens in fire test. In the experimental program of this study, the two specimens were tested at elevated temperatures in the furnace and under the specified constant loadings, and the moment connections of the two specimens were made of fire-resistant steel and normal steel respectively for comparison.

本研究针对两支实尺寸H型梁-箱形柱接合之耐火钢与普通钢弯矩接头试体受定载加温的火害行为进行ABAQUS有限元素数值模拟，所得之数值结果分别与两支试体在大型高温炉中所进行的火害试验结果比对，以验证有限元素数值模型之正确性。

This member model consists of isolating macroscopic member element into three subelements, namely spread plastic beam subelement, joint slip subelement and shear subelement, and thus the stiffness matrix of the frame member element can be easily constructed by calculating the fl...

该单元模型能够考虑非线性变形随复杂加载历史在端部关键受力区域的逐步扩展和反弯点位置的移动，整个推导过程力学概念明确，所获得的柔度矩阵为对称矩阵，便于数值计算。

In this paper, material properties of the segment of the porous metal-bonded diamond grinding wheel were researched by finite element simulation. Segments were manufactured according to the design result and their elastic modulus was measured. The key points are as follows: The influence of the porosity on the elastic modulus was analyzed through a finite element method. In the FEM model, the design variable only includes the porosity, and the tetrakaidecahedron model is applied as the microstructure model of porous metal matrix. The corresponding porosity was decided in order to meet the requirement of the elastic modulus.

本文利用有限元软件对多孔金属结合剂金刚石砂轮节块的材料性能进行了数值模拟计算，依设计结果制备了节块试样，并测试了节块的弹性模量，主要内容有： 1、充分借鉴多孔材料结构设计和分析的方法，以十四面体模型为多孔金属胎体的微观结构模型，以孔隙率为设计变量，通过有限元分析，计算出满足一定弹性模量要求的多孔金属胎体的孔隙率范围。

A tetravalent nonmetallic element; next to oxygen it is the most abundant element in the earth's crust; occurs in clay and feldspar and granite and quartz and sand; used as a semiconductor in transistors.

一种四价非金属元素，地壳中含量仅次于氧，见于粘土、长石、石英和沙中，在晶体管中用作半导体。

The results show that a sound bonded interface is obtained without sheet inclusion, pore and unbinding. The microstructure consists of bulk α-Mg phase and needle compound in the weld metal, element Al diffuses along the grain boundary of the substrate into the welding line. A little Y diffuses into the base metal. A little Mn and Cu segregate and element Ni distributes homogeneously and no segregation appears in weld area.

结果表明：界面接合良好，未观察到片状夹杂物、气孔及未焊合等缺陷；焊缝区由块状α-Mg相和针状化合物组成，基体中的Al元素通过晶界扩散偏聚到焊缝中，微量Y元素扩散到基体中，有少量的Mn和Cu元素发生偏聚，Ni元素分布均匀，没有发生偏聚现象。

Furthermore, it is presented that if I is a two-sided ideal of a unital ring R and I is an exchange general ring,then every central element of I is a clean element in I.

还证明了如果环R的双边理想I是一个exchange一般环，则I的每一个中心元素都是I中一个clean元素。

"Yes, now you can give yourself airs," she said, you have got what you wanted.

"对了，您现在高兴了，"她说道，这是您所期待的。

Then the LORD said to me: Rebel Israel is inwardly more just than traitorous Judah.

上主于是对我说：＂失节的以色列比失信的犹大，更显得正义。