查询词典 aminopyrine

On the other hand, the hepatic microsomal aminopyrine demethylase activity was obviously inhibited 2 hours after administration of the same dose of SY-801 and SY-640, while the content of hepatic cytochrome P-450 was not affected.

体外实验表明，SY-801和SY-640对正常小鼠、3-甲基胆蒽（3-MC）处理小鼠及苯巴比妥处理小鼠小鼠肝微粒体氨基比林脱甲基酶活性都具有明显的抑制作用，其中对3-MC处理小鼠肝微粒体氨基比林脱甲基酶活性抑制作用最显著。

Liquid phase microextraction ; Aminopyrine ; Antipyrine ; Barbital ; Gas chromatography

液相微萃取；氨基比林；安替比林；巴比妥；气相色谱

Here we show that VacA permeabilizes the apical membrane of gastric parietal cells and induces hypochlorhydria.The functional consequences of VacA infection on parietal cell physiology were studied using freshly isolated rabbit gastric glands and cultured parietal cells.Secretory activity of parietal cells was judged by aminopyrine uptake assay and confocal microscopic examination.

为此，我们建立了原代培养的胃腺、胃壁细胞等研究模型和良好的评估壁细胞分泌能力的技术平台，包括氨基比林吸收实验、激光共聚焦扫描技术等，对VacA感染所导致的壁细胞生理特征的改变进行了深入细致的研究。

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响，结果表明SY-801和SY-640体内连续给药3天，可诱导小鼠肝微粒体细胞色素P-450含量明显增加，同时氨基比林脱甲基酶活性亦明显增加；给药1次2小时内二者均可抑制氨基比林脱甲基酶活性，而对肝微粒体细胞色素P-450含量则无明显影响。

Methods The activities of liver microsomal erythromycin N-demethylaseand aminopyrine N-demethylase were measured by spectrophotometry. The levels of mRNA expressions of CYP3A1, CYP1A2, CYP2E1, mdrla and mdrlb in hepatic microsome were determined with RT-PCR method.

用分光光度法测定大鼠肝微粒体红霉素N-脱甲基酶、氨基比林N-脱甲基酶的活性，用逆转录聚合酶链反应技术测定大鼠肝脏CYP3A1、CYP1A2、CYP2E1、mdr la和mdr lb基因的水平。

Mehtod: animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥（40mg/kg.d）、葛根素（100和200 mg/kg.d），给药7d后，用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量，以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Mehtod: The animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥（40mg/kg.d）、葛根素（100和200 mg/kg.d），给药7d后，用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量，以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Activities of Aminopyrine N-demethylase, Ethoxycoumarin O-deethylase and Glutathione S-transferase in the hepatopancreas and gills of Fenneropenaeus chinensis were measured by UV spectrophotometry and fluorospectrophotometry. The effects on the activities of APND and ECOD、GST in the hepatopancreas and gills were studied following multi-oral baicalin.

用紫外分光光度法及荧光分光光度法测定中国对虾肝胰腺及鳃氨基比林－N-脱甲基酶、乙氧基香豆素－O-脱乙基酶、谷光甘肽－S-转移酶几种药物代谢酶的活性，探讨黄芩苷对上述几种酶活性的影响。

For example: antimalarials primaquine morpholine, flutter malaria quinoline, quinine, chloroquine, quinacrine; antibacterial drugs have sulfa drugs, chloramphenicol and furans; antipyretic analgesics are acetyl salicylic acid, phenacetin, acetanilide, antipyrine, aminopyrine; other drugs such as vitamin K, probenecid, hydralazine, quinidine, methylene blue, toluene and so on.

抗疟药伯氨喹啉、扑疟喹啉、奎宁、氯奎、阿的平；抗菌药有磺胺类药物、氯霉素及呋喃类；解热镇痛药有乙酰水杨酸、非那西丁、乙酰苯胺、安替比林、氨基比林；其它药物如维生素K、丙磺舒、肼苯哒嗪、奎尼丁、美蓝、甲苯等。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。