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Subcellular location of apoptosis proteins is closely related to their function. According to the concept that the subcellular location of an apoptosis protein is mainly determined by its amino acid sequence, the six kind of subcellular locations of apoptosis proteins are predicted by using of the algorithm of the increment of diversity combined with support vector machines based on the n-peptide components of global, local amino acid sequence and hydropathy and hydrophobicity.

基于一个凋亡蛋白的亚细胞位置主要决定于它的氨基酸序列这一观点，选取局部氨基酸序列的肽组分和序列的亲疏水性分布信息，采用离散增量结合支持向量机算法，对六类细胞凋亡蛋白的亚细胞位置进行预测。

According to the concept that the subcellular location of an apoptosis protein is mainly determined by its amino acid sequence, the six kind of subcellular locations of apoptosis proteins were predicted by using the algorithm of the increment of diversity combined with support vector machines based on the n-peptide components of local amino acid sequence and hydropathy and hydrophobicity.

根据凋亡蛋白的亚细胞位置主要决定于它的氨基酸序列这一观点，基于局部氨基酸序列的n肽组分和序列的亲疏水性分布信息，采用离散增量结合支持向量机算法，对六类细胞凋亡蛋白的亚细胞位置进行预测，结果表明，在Re-substitution检验和Jackknife检验下，ID—SVM算法的总体预测成功率分别达到了94.6％和84.2％；在5-fold检验和10-fold检验下，其总体预测成功率也都达到了83％以上。

OrLPT1 ORF encods a polypeptide with 535 amino acid residues (molecular mass of 57.6KDaltons), which shares more than 64% amino acid identity with some other high-affinity Pi transporters of plants. Hydropathy analysis of the deduced polypeptides showed that the OrLPT1 is highly hydrophobic and contains 12 putative membrane-spanning regions.

OrLPT1 ORF 编码长为535 个氨基酸(分子量57.6 KDaltons)的蛋白，与其他植物物种磷酸盐转运蛋白的同源性在64%以上；多肽链的疏水性分析表明，OrLPT1 具有12 个疏水的跨膜区及高亲和力磷酸盐转运蛋白中保守的3 个磷酸化作用位点：蛋白激酶C作用位点、N端糖基化部位和酪蛋白激酶II 作用部位； 3。

The 3D structure of N protein shows that the domain of Ep703 is exposed on the surface of the protein, making the epitope to be readily recognized by antibody. No homology is found between the mimotopes and native epitope. However, they all contain high content of hydrophile amino acids and low content of hydrophobile amino acids.

蛋白的三维结构显示，Ep703的9个氨基酸多肽暴露于蛋白的表面。3个模拟表位与表位Ep703的序列&IQTAFNQGA&相比，相同的氨基酸很少，但是各表位氨基酸的极性却有一个共同的特征：亲水性氨基酸比例较大，疏水性氨基酸比例较少。

The polar hydrophilous amino acid Thr is replaced by an unpolar hydrophobous amino acid Ile, a hydrogen bond changed in the higher structure and the point is far away from the active center, so it doesn't influence the activity and thermostability a lot.

亲水的Thr108突变成非极性的Met，导致与该位点空间相邻的N116亲水氨基酸His的极性残基——咪唑环产生空间电位排斥，从而造成His所在的β折叠构象发生改变。

It looks like that the molecular weight of these immunopeptides were very small, and it also showed that the hydrophobe amino acid on the bottom and alkaline amino acid were important structurals of the immunopeptides.

论文主要研究结论如下：目前已报道的140余种免疫活性肽其相对分子质量都较小，通常在肽链中含有碱性氨基酸或在末端具有疏水性氨基酸。

It is shown by Infrared spectra that relative concentration of amino formic acid ester has prominent relationship with compressive stress at 10% strain in the process of accelerated hygrothermal tests, which means that hydrolysis of amino formic acid ester is main factor resulting in decrease of compressive properties.

经红外光谱测定，在人工加速湿热老化试验过程中，材料的活性基团氨基甲酸酯的相对浓度与10%定应变压缩应力的相关性显著，氨基甲酸酯水解是材料室内贮存过程中力学性能下降的主要原因。

One of the amino acids, called prolene, is not really an amino acid, but imino acid.

有一种称为脯氨酸的氨基酸实际上并不是氨基酸，而是亚氨基酸。

E. the activation of amino acid, the elongation of peptide chain and the termination of the chain reaction, among which the activation of amino acid—the formation of imino acetoxyphosphoranes was the key step.

在这三步中，氨基酸的活化即氨基酸磷烷的形成是整个自组装成肽反应的最重要一步。

Racemic backbones 2-amino-2'-hydroxy-6,6'-dimethyl-l,l'-biphenyl la and 2-amino-2'-hydroxy-4,4',6,6'-tetramethyl-l,1'-biphenyl 1b were synthesized from o-methylaniline and 2,4-dimethylaniline via nitration, diazotation/iodination, Ullmann coupling, selective reduction, diazotation/hydrolysis and hydrogenation.

从邻甲苯胺及2，4-二甲基苯胺出发，经过硝化，重氮化-碘代，偶联，单还原，重氮化-水解及还原反应合成了消旋体骨架2-氨基-2'-羟基-6，6'-二甲基-1，1'-联苯1a和2-氨基-2'-羟基-4，4'，6，6'-四甲基-1，1'-联苯1b。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。