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As a fault basin, Jiyang depression experienced multicycle evolvements, and the developing characteristics of the faults in each structural stage controlled not only the prototype basin pattern, but also the denudation and alteration of the previous basin.

作为断陷盆地，济阳坳陷自中生代以来，经历了多期次的盆地演化过程，各时期的断裂发育特征不仅控制了当时的原型盆地格局，也主导着对先期盆地的剥蚀改造，盆地的叠合关系直接控制了残留盆地格局。

In this study, we investigate the heat-induced inhibition of drug-metabolizing enzyme activity in mice fed with freeze-dried, heated freeze-dried or half amount autolyzed freeze-dried Brussels sprouts powder. 0.5% ethoxyquin diet was fed to another group of mice as a positive control. The study mice, four per group, were fed a diet consisting of 20% Brussels sprouts for 7 days. Each group had its own pair-fed group. We found significantly greater inductions of glutathione S- transferase, quinine reductase, and phase Ⅱ drug-metabolizing enzyme activities in groups fed within freeze-dried and heated freeze-dried Brussels sprouts than their pair-fed groups. These findings indicate that intestinal microflora still can hydrolyze glucosinolates without plant myrosinase activity, though the alteration of cytochrome- P-450 1A (CYP1A, a phase Ⅰ drug-metabolizing enzyme) induction was only 1.4-fold.

本实验欲进一步探討加热处理之抱子甘蓝对phase Ⅰ与phase Ⅱ解毒酵素活性之影响差异，实验分三组，抱子甘蓝(1)冷冻乾燥组（glucosinolate未裂解）(2)加热冷冻乾燥组(3)半量之裂解冷冻乾燥组（glucosinolate已裂解），(4)and 0.5% ethoxyquin diet was used as a positive control以2%重量混合成饲料，餵以小白鼠（4只／组）7天，结果发现，在第(2)组小白鼠GST phase Ⅱ酵素）活性显著上升，显示在植物裂解酵素不存在之状况下，肠胃道之微生物仍可促进裂解反应，但由CYP1A活性增加不显著（仅1.4倍）看来，根据定义：单独phase Ⅱ酵素活性增加，为monofunctional induction/inducer，可加速致癌物之代谢。

In addition, NAIS may use or provide a third party with such analysis and statistic information if necessary for management, use, maintenance, alteration, promotion, propagation, and academic research and there is no disclosure of personal information.

本平台并得於管理，使用，维护，修改，宣传，推广以及进行学术研究之必要范围内，自行或提供第三人使用该统计，分析资料，不涉及个人资料之揭露。

In addition, NAIS may use or provide a third party with such analysis and statistic information if necessary for management, use, maintenance, alteration, promotion, propagation, and academic research.

所上传之部分影音资料与完整影音资料之比例，与附表所示者相符时，可被认为属於合理使用。

In addition, NAIS may use or provide a third party with such analysis and statistic information if necessary for management, use, maintenance, alteration, promotion, propagation, and academic research.

一资料提供者了解其对所上传之影音资料(包含影音，图片与文字等)有完整之权利，且同意「国家影音产业资讯平台」之使用者得自由浏览本影音资料。

It is suggested that combining P3 with neuropsychological tests could well reflect the alteration of cognitive function.

而P3检查与神经心理测查相结合，能更全面地反映认知功能的变化。

Thus, we suggest that GlyRs is a molecular target of E_2 which directly binds to and noncompetitively modulates GlyRs, leading to the alteration of neuronal excitability and contributing to the estrogenic effects in hippocampus and the early CNS development.

与HEK293细胞中结果一致，E_2对脊髓神经元I_的抑制作用随神经元的培养时间逐渐减弱；但在培养海马神经元上，E_2对I_，的抑制作用则不随神经元培养时间延长而变化。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

The present paper deals in detail with the origin, dynamics, geochemistry and physicochemistry of the ore-forming fluids, in combination with the origin of ore-forming matter, gold behaviour in the ore-forming fluids, equilibrium and unstability-precipitation in the course of migration on the basis of mineral composition and mineralization, alteration and ore-controlling factors of the representative gold deposits hosted in the Ailao Mountains ophiolitic melange belt, Yunnan.

笔者通过哀牢山蛇绿混杂岩带典型金矿床的物质组成、成矿规律、蚀变及控矿作用的研究，对哀牢山金矿带的成矿流体来源，成矿流体动力学、地球化学及物理化学性质进行了详细地讨论；对金矿的成矿物质来源，金在成矿流体中的存在形式，迁移过程中平衡、失稳-沉淀等进行了详细地分析和探讨。

To eplore the relationship between Dynein and the formation of meiosis error of oocytes, the immature mouse oocytes were in vitro cultured with a known dynein ATPase activity inhibitor- sodium orthovanadate to detect the changes of maturation rate, and semi-quantitative RT-PCR and single cell RT-PCR were performed to detect the alteration of the cyclin B1 mRNA level.

为探讨Dynein与卵母细胞减数分裂错误形成的关系，采用小鼠卵母细胞体外培养成熟技术和半定量RT-PCR方法，分别检测Dynein抑制剂-原钒酸钠对卵母细胞成熟率和cyclin B1基因转录水平的影响。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。