查询词典 all-time

The analysis of AL, especially ALL aneuploid, by image analysis system can be helpful in distinguishing the high risk ALL from the standard risk ALL ,and the determination of cell cycle distribution can provide a crucial reference data for chemotherapy.

图像分析系统对AL尤其是ALL异倍体的分析，有利于判断高危ALL，对细胞周期的测定给化疗个体化提供了具体的参考指标。

The intersection of the two All members is the grand sales total of all products to all customers.

两个 All 成员的交叉点就是所有客户，所有产品的销售总额。

FESTIVAL OF ALL SAINTS, also formerly known as ALL Hallows, or Hallowmas, a feast of the Catholic Church celebrated on the 1st of November in honor of all the saints, known or-unknown.

FESTIVAL OF ALL SAINTS 原来叫作ALL Hallows或Hallowmas，无论知名与否，天主教堂为了表示对所有的圣人敬意，于11月1日设盛宴进行庆祝活动。

Put all one's heart and soul to do something 常用作to do something with all one's heart and soul.比如上句就可以改写为:The most important point view of his speech was that we should work for the people with all our heart and soul.

结束语：当面临着各种挑战时，人类绝不会退缩让步，虽然SARS给我们的生存带来了极大的压力，但全世界的医务工作者们却全心全意的（put all their heart and soul to do something）扑在抗击非典的战斗中，可以说他们才是全世界最可爱的人。

Restrictive changes of TCR Vp repertoire and clonal expanded T cells could be found in peripheral blood T cells from patients with T-ALL. However, the clonal expanded T cells' property (clonal expansion leukemic cells or leukemia antigen-specific expansion T cells) should be further characterized. It may play a certain role on detection of minimal residual disease and design of anti-leukemia idiotypic vaccine. The dominant utilization of TCR VjJ repertoire could be found in peripheral blood T cells from patients with B-ALL, meanwhile clonal expansive T cells were existed. It may be a feature of the host immune response for leukemia-associated antigen. The clonal expansive tendency of T cells in V021 and VP23 subfamilies was rather obvious, which may be correlated with certain malignant B-cell clone. The CDR3 sequences of monoclonal expansive T cell in T cell strains were different, which was the base of developing DNA vaccine.

T-ALL患者外周血T细胞的TCR Vβ谱系出现限制性改变，均可检测到克隆性增殖T细胞，尚需进一步鉴定其性质(肿瘤性或抗原特异性增殖)，对于研究微小残留病变检测和设计抗白血病独特型疫苗均有一定的意义。B-ALL病人外周血T细胞的TCR Vβ谱系呈现优势利用的特点，并存在克隆性增殖的T细胞，这可能是机体对白血病相关抗原产生的特异性免疫反应；Vβ21和Vβ23亚家族T细胞发生克隆增殖改变的趋向性比较明显，可能与B-ALL相关抗原刺激有关。T细胞株中检测到的肿瘤克隆其CDR3序列具有高度的特异性，是构建DNA疫苗的基础。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

All of the Subject-verb agreement: all of the singular and plural by its modification or refer the decision of the singular and plural nouns.

all 的主谓一致：all的单复数由它所修饰或指代的名词的单复数决定。

I don't bui it at all.all the nfl jerseys are of high quality at lowest price.

我不裴在all.all它的NFL球衣是在价格最低的高品质。

Results: 5~12 Vβ subfamilies were identified in 6 T-ALL cases and 2~18 Vβ subfamilies were identified in 13 B-ALL cases, respectively.

结果：6例T-ALL病人分别表达5～12个Vβ亚家族，13例B-ALL病人分别表达2～18个Vβ亚家族。

The fourth was astounding.I saw a woman disguised in her maid's clothes hear her husband speak the first tender words he's offered her in years.Simply because he thinks she is someone else.I heard the music of true forgiveness filling the theater conferring on all who sat there, perfect absolution.God was singing through this little man to all the world.Unstoppable.

那段二重唱是很美丽，但我还是喜欢第四幕里gente，gente， all'armi， all'armi那一段，那是我在米洛斯福尔曼的传记电影莫扎特里感染到的，在最后一幕里费加罗的未婚妻装扮成女仆然后她的未婚夫-当然就是费加罗当着她的面在说他有多么的爱他的未婚妻，因为他重来没有尝试这表达，而他今天表达的只应为他并不知道女仆就是她的未婚妻。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失