查询词典 agonist

In the middle rostrocaudal third of the red nucleus,the double-labelled neurons mainly occupied the ventromedial portions of the red nucleus.Injection of Bay K8644 (an L-Ca2+ channel agonist) in lateral ventricle induced immunoreactive intensity and did not change the distribution pattern of CaBP-LI positive rubrospinal neurons.

脑室注射L型钙离子通道激动剂Bay K8644 仅引起CaBP-LI免疫反应强度增加，并未改变两种神经元的分布方式，头侧CB-Au标认的红核-脊髓投射神经元仍表现CaBP-LI阴性。

Injection of Bay K8644 (an L-Ca2+ channel agonist) in lateral ventricle induced immunoreactive intensity and did not change the distribution pattern of CaBP-LI positive rubrospinal neurons.Rubrospinal neurons in the rostral portion still showed CaBP-LI negative.

脑室注射L型钙离子通道激动剂Bay K8644 仅引起CaBP-LI 免疫孕妇反应强度增加，并未改变两种成年人神经元的分布方式，头侧CB-Au标认的红核-脊髓投射成年人神经元仍表现CaBP-LI阴性。

Injection of Bay K8644 (an L-Ca2+ channel agonist) in lateral ventricle induced immunoreactive intensity and did not change the distribution pattern of CaBP-LI positive rubrospinal neurons.Rubrospinal neurons in the rostral portion still showed CaBP-LI negative.

脑室注射L型钙离子通道激动剂Bay K8644 仅引起CaBP-LI免疫反应强度增加，并未改变两种神经元的分布方式，头侧CB-Au标认的红核-脊髓投射神经元仍表现CaBP-LI阴性。

To date, there have been a few clinical trials exploring the efficacy of NMDA enhancers as adjuvant therapy. For instance, D-serine (an endogenous agonist of the NMDA-glycine site) and sarcosine (N-methylglycine, an endogenous glycine transporter I inhibitor) are not only well-tolerated but also synergistic in improving positive, negative symptoms and cognitive function in chronic patients receiving typical or atypical antipsychotics. We just completed the first trial applying NMDA enhancers in acutely exacerbated schizophrenia patients with collaboration with Harvard University, and the results showed that sarcosine was superior to D-serine in efficacy.

目前已有将NMDA促进剂作为辅助用药的临床研究，例如，D-serine (一种内生性NMDA-glycine site致效剂)、sarcosine (即N-methylglycine，一种内生性glycine transporter I 抑制剂)等，结果显示它们不但安全，且能加强传统及新一代抗精神病剂对慢性患者活性、负性症状及认知功能的疗效；我们日前与哈佛大学合作完成目前唯一将NMDA促进剂用於急性患者的研究，结果发现，sarcosine的疗效又优於D-serine。

The opioid receptor agonist at the supraspinal site failed to alter the pelvic nerve activity suggest that supraspinal endogenous opioid system does not act directly on the sacral preganglionic neurons, but indirectly through descending fibers on the interneuron at the level of afferent inputs in the sacral spinal cord.

由於注射此药物到侧脑室中，并不会对骨盆神经之活性造成影响，因此推论上脊髓部位的内吗啡系统，并不会直接影响副交感神经节前神经元之活性，其作用可能在中问神经元或膀胱的输入神经。

Clonidine (20ug/bilateral), an alpha agonist, produced similar effect as NA; while phentolamine (10ug/unilateral), an alpha antagonist, brought about an enhancement of AA, This phenomenon was observed in the acupuncture effective group, but not in the acupuncture uneffective one. However, propranolol (10ug/unilateral), a beta antagonist, had no effect on AA in these two groups.

结果表明，微量注射NA（0.5μg/单侧）能部分翻转针刺镇痛作用；α受体激动剂可乐定（20μg/双侧）也有同样作用；而α受体拮抗剂酚妥拉明（10μg/单侧）可以显著加强针刺有效组家兔的针刺镇痛作用，但对针刺无效组的痛阈无明显影响；β受体拮抗剂心得安（10μg/单侧）则对针刺有效或无效组的痛阈均无显著作用。

Conversely, injury to the reticulospinal or vestibulospinal tracts, which normally inhibit spinal reflex pathways, results in "positive" symptoms including spasticity, hyperactive muscle stretch reflexes, abnormal cutaneous and autonomic reflexes, and co-contraction of agonist and antagonist muscles.

相反，一般不影响脊髓反射通路的皮质脊髓束和小脑脊髓束的损伤导致阳性效应，包括痉挛、牵张反射亢进、病理的皮肤反射和自主反射、相互拮抗肌的共同紧张。

Objective : To observe the effect of gonadotropin - releasing hormone agonist on steroidogenesis of cultured human luteinized granulosa cells in vitro.

目的：观察促性腺素释放激素激动剂在体外对人卵巢黄素化颗粒细胞雌二醇(E2)和孕酮分泌量的影响。

The intracerebroventricular injection of ACh increased the pain-evoked discharge frequency and shortened the latency of PEN,decreased the pain-evoked discharge frequency and prolongated of the inhibitory duration of PIN in LC of the normal rats.2）The intracerebroventricular injection of M-receptor agonist pilocarpine was similar to the effects of ACh.

侧脑室注入ACh能够使正常大鼠LC中痛兴奋神经元痛诱发放电频率增加、潜伏期缩短，痛抑制神经元痛诱发放电频率减少，诱发放电完全抑制时程延长，而后逐渐恢复；2）侧脑室注入毛果芸香碱能够产生与ACh相似的效应。

Rets: after treated by salbutamol sustained release capsule for 2 wk, nocturnal and daytime symptoms were significantly improved, inhaled β2 adrenoreceptor agonist use was reduced, the integrated effective rate of nocturnal and daytime symptoms was 57％ and 60％, respectively, value of fev1 was markedly enhanced and the daily variance rate of pefr was evidently reduced as compared with baseline, the efficacy was similar with that of bambuterol.

结果：沙丁胺醇缓释胶囊治疗2wk后，日夜间症状评分显著下降，按需吸入β2受体激动剂用量显著减少，日、夜间症状综合疗效的有效率分别为57％和60％，fev1较治疗前显著上升，每日pefr变异率较治疗前显著降低，其疗效与班布特罗相似。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷