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The results showed that UK14300 3×10~(-6 mol/L, a potent #alpha#_(2)-adrenoceptor agonist,significantly inhibited both basal and endotoxin-induced CGRP release by 22%-42%,while specific antagonist of #alpha#_(2)-adrenoceptor yohimbine 10~(-5 mol/L blocked the effect of UK14304 completely.

结果发现，α_(2)-受体激动剂UK143043×10~(-6mol／L可以显著抑制CGRP的基础释放和内毒素(1～5μg／ml)刺激后的释放，抑制幅度为22％～42％；用α2-受体拮抗剂Yohimbine(10－5mol／L)可以完全阻断UK14304的作用。

Binding of the P2Y12 receptor by its agonist, ADP, activates the G-protein inhibitor secondary messenger system, which, through a complex series of events, mediates the completion and amplification of the aggregatory response.7 Ticlopidine and clopidogrel are prodrugs that are converted to an active metabolite through a 2-step process mediated by the hepatic cytochrome ...

氯吡格雷和抵克立得作为药物前体，都可通过肝脏细胞色素P450介导的两步反应过程转化为活性代谢物…。。

It has been well established that agmatine is an endogenous agonist at imidazoline receptors and noncatecholamine ligand at alpha - 2 adrenergic receptors (α2- AR).

业已证明，胍丁胺是一种内源性的咪唑啉受体激动剂和α2-肾上腺素能受体（α2-AR）的非儿茶酚胺配基。

Objective The experiment studied the effects of acetylcholine and M-receptor agonist pilocarpine on the electric activities of the pain-related neurons in the locus ceruleus of normal rats,in order to further study the role and the interaction of ACh and LC in the modulation in the algetic sense.

目的 本实验观察大鼠侧脑室内加入外源性乙酰胆碱后，蓝斑核（Locus ceruleus，LC）痛反应神经元的电变化，以及M受体激动剂毛果芸香碱的激动效应，进一步研究ACh和LC在痛觉调制中的作用及其相互关系。

The infusion of DADLE, a δ-opioid receptor agonist, produced a dose-dependent increase of ARNA without affecting renal pelvic substance P release, urine flow rate, and urinary sodium excretion.

此外，从肾盂灌注类鸦片致效剂DADLE([D-Ala2， D-Leu5]-enkephalin)，则会有一浓度依存性的增加ARNA的活性，但却不会影响肾盂内物质P的释放及对侧肾脏尿液流速(urine flow rate， UV)和钠离子排泄率(urinary sodium excretion， UNaV)；而此ARNA的增加并不会因预先给予NK-1受体拮抗剂spantide I (0.1mg/ml， 20μl/min)而有所减少。

Based on the synthesis method and the function of decreasing blood glucose levels of rosiglitazone, and the report on benzoquinones which resulted in a significant decrease in blood glucose levels, a novel non-thiazolidinedione class of PPARy agonist 2, 5-Dihydroxy-3-{4-[2-(methyl- pyridin-2- yl-amino)- ethoxy] -phenyl}-6-phenyl-[l, 4] benzoquinone (4) was designed and synthesized.

在合成罗格列酮的基础上，根据某些醌类结构化合物的类似胰岛素作用，设计并合成了一种非噻唑烷二酮类PPARγ激动剂2，5-二羟基3-{4-[2-(甲基-2-吡啶氨基)-乙氧基]-苯基}-6-苯基-1，4苯醌(4)。

Most recently, incensole acetate was isolated from Boswellia carterii and shown to be a potent TRPV3 agonist and cause anxiolytic-like and antidepressive-like behavioral effects in mice with concomitant changes in brain c-Fos activation, a marker for changes in neuronal activity.

上图为常用的制香原料，从上到下，从左至右，为：抹香，冰片，苏门答腊安息香胶，阿曼乳香，Guggul，黄金乳香，妥鲁香，索马里没药，劳丹脂，Opoponax，和印度白檀粉。

The ventilatory responses of the peripheral chemoreflex following microinjection within the NA of either P2X receptor agonist adenosine triphosphate or antagonist pyridoxal-5′-phosphate-6-azo-phenyl-2, 4-disulfonate were observed.

结果 吸入低氧混合气后，动物呼吸加深加快；在NA处微量注射ATP增强了急性低氧呼吸频率，微量注射PPADS部分阻断了ATP对低氧通气的兴奋效应。

Morphometry of numerical density and electron probe X-ray quantitative microanalysis were adopted to measure the alterations in the number and calcium content of chromaffin granules in adrenal medulla cells during the agonist treatment. Secretion of epinephrine was detected by the high performance liquid chromatography.

运用细胞立体形态计量法计算分泌过程中的嗜铬颗粒数目的变化，运用电镜X射线显微分析法测量分泌过程中嗜铬颗粒内钙含量的变化，并运用高压液相色谱分析法测定离体细胞在激动剂作用后的肾上腺素分泌情况。

WEH only contained small amount of chrysin, but in consistent with the literature chrysin was a BDZ agonist.

黄苓甘不与BDZ结合处结合；泛黄苓素为BDZ拮抗剂；而在黄苓水抽提物中含有微量chrysin，其为BDZ作用剂，与文献报导吻合。

As of Tuesday, Google's results were still censored in China.

截至周二，谷歌的搜索结果仍受中国审查。

In order to make the positive action increase and negative one decrease, the sub-forces of the social factors must be adjusted to form a centripetal force.

在这一过程中，人的主体性发挥是社会有机体健康发展的灵魂。