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The results show that the hyperalgesia of OFQ and its antagonization on AA in PAG are dose-related. OFQ in PAG decreases the enhancing effect on AA induced by ohlnefentanyl, a selective μreceptor agonist.

结果表明：PAG内微量注射OFQ可使大鼠痛阈降低，并明显对抗针刺镇痛；另外还发现，OFQ在PAG内还可以对抗μ受体激动剂羟甲芬太尼加强针刺镇痛的效应。

The GABAB agonist baclofen is approved as an antispasmodic, but has been used to inhibit TLESR and reflux in humans.

巴氯芬是一种B型GABA受体激动剂，被批准作为解痉剂使用，但在人类已被用于抑制TLESR及反流。

Apomorphine, agonist on DA receptor, has been proved to be effective revulsant of penile erection.

提示雄激素可能通过调节MPOANOS的表达或活性间接影响DA的释放。

One of the problems we have seen I that when we give a drug that reduces appetitive like the Melanocortin 4 receptor agonist, that that tends to raise the blood pressure and of course that is undesirable in treating hypertensive patients to have a further rise in blood pressure so we would like to understand the molecular signaling pathways in the brain that allow for appetite, metabolic function, and blood pressure to be differentially controlled and therefore attack those different targets in treating not only obesity but also hypertension.

我们所遇到的一个难题是，当我们使用一种药物减低食欲，如黑皮质素受体4，有可能会增加血压。当然，血压进一步升高对于治疗中高血压患者是不受欢迎的。所以在高血压和肥胖的治疗中，我宁愿了解脑影响食欲、代谢功能和血压的分子信号途径，由此寻找差异性控制、进而治疗不同的目标。

Management of the bradycardia withβ-adrenergic receptor agonist,such as salbutamol,to activate cardiac sympathetics may be more available.

使用β-肾上腺能受体激动剂激活心脏交感神经的活性，能获得良好的临床治疗效果。

Objective To study the effect of dopamin receptor agonist and antagonise in caudate nucleus on the cardiovascular function .

：大鼠尾核可通过多巴胺受体起作用参与心血管活动的调控。

Removal, in particular, of these descending inhibitory influences leads to an overactivity of the spinal reflex arc resulting in an increase in muscle tone, hyperreflexia, extensor plantar response, flexor spasms, clonus, and co-contraction of agonist and antagonist muscles.

脊髓灰质以上的损伤可以导致协同运动、无力和灵巧性降低。认领"药物治疗"。已经校正了，有一些出入。

March 26, 2003 The mu agonist levorphanol is effective for neuropathic pain, according to the results of a randomized, double-blind study published in the March 27 issue of the New England Journal of Medicine . Higher doses reduced pain more than lower doses but had greater adverse effects limiting the additional benefit. An editorialist puts this into perspective, suggesting that this adds to the evidence countering the opinion that neuropathic pain is opioid-resistant.

March 26， 2003 -根据一项发表於3月27日「新英格兰医学期刊（New England Journal of Medicine）」的随机、双盲试验结果显示，mu作用剂levorphanol可有效治疗神经性病变的疼痛，而且高剂量的疼痛缓解作用比低剂量好，但相对地，副作用也较大；随后的评论则表示这个研究结果与过去所认为神经病变所引起的疼痛对鸦片类药物具有抗性的说法相反。

The experiment ofβ2 agonist screening showed that compatibilities with ephedra had the activity of relieving asthma.

2激动剂筛选实验表明，含有麻黄的配伍都有平喘活性，麻黄和甘草的组合活性更强。

Hurry did not hesitate, but the kick that had actually destroyed one fellow creature was no sooner given than he closed in with this formidable agonist.

赫利毫不迟疑，他一脚把那个可怜的家伙送往黄泉以后，立刻就向这个威武的对手扑来。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。