查询词典 agonist

The plasma concentration (10-6 M) following I administration in patients with ARDS may be sufficient to stimulate AFC if a similar concentration reaches the airspaces. Aerosolised deliery of a beta-2 agonist can achiee higher concentrations in the distal airspaces and maximal AFC.

讨论：ARDS患者中静脉使用舒喘灵达到血浆浓度10-6 M（如果气腔内达到同样的浓度）可以有效刺激AFC，雾化吸入的β 2–激动剂可以在末稍气腔内达到更高的浓度和最大的AFC。

The alpha-2 agonist is a sedative with analgesic and anxiolytic properties. It was granted FDA approval in December 1999 for use in patients in intensive care settings.

在针对镇静与麻醉药物会议中对听众进行的投票，大约仅有10%的听众表示，经常每周多於一次，对需要镇静与麻醉的病患使用dexmedetomidine；大约70%的听众表示，他们从未使用过这个药物。

The alpha-2 agonist is a sedative with analgesic and anxiolytic properties. It was granted FDA approval in December 1999 for use in patients in intensive care settings.

在针对镇静与麻醉药物会议中对听众进行的投票，大约仅有10%的听众表示，经常每周多于一次，对需要镇静与麻醉的病患使用dexmedetomidine；大约70%的听众表示，他们从未使用过这个药物。

Background: Dexmedetomidine is a highly selective α2-adrenoreceptor agonist possessing analgesic, anxiolytic, and sedative properties.

背景：Dexmedetomidine是一种高选择性α2肾上腺受器促效剂，具有止痛、解郁和镇静的效果。

Other research is looking at how disulfiram, an indirect dopamine agonist, might be useful to treat cocaine addiction. By inhibiting the enzyme dopamine beta-hydroxylase, which converts dopamine to norepinephrine, disulfiram reverses stimulant-induced dopamine deficiency, Dr. Kosten explained.

Kosten医师解释，其他研究针对disulfiram是如何作用的，这是一个间接多巴胺致效剂，可能可以有效地治疗成瘾；透过抑制多巴胺贝他水解酵素，这个酵素将多巴胺转换成正肾上腺素，disulfiram逆转刺激剂诱发的多巴胺缺乏。

To assess which Ser/Thr residue could act as a phosphate acceptor upon agonist stimulation, truncation mutants of DORs were constructed by removing the last 15 ( D 15) or 31 ( D 31) residues containing the last three or six potential phosphorylation sites from the C-terminus of the wild-type receptor.

为了研究激动剂诱导下DOR的磷酸化发生于哪一个位点，我们首先构建了C末端区缺失六个丝/苏氨酸残基及三个丝/苏氨酸残基的DOR突变体 D 31和 D 15。

In control experiments, 10 nM of Tyr-D-Ala-Gly-Me-Phe-Gly-ol, a synthetic enkephalin and specific mu agonist, activatedthe MOR-1, whereas 20 mM of glucose had no effect.

结果为对照实验中， 10 nM 的 Tyr-D-Ala-Gly-Me-Phe-Gly-ol（一种人工合成的脑啡肽，为μ受体特异性激动剂）可激动 MOR-1；而20 mM 的葡萄糖却并没有作用。

Expression of human β-arrestin 1 attenuated κ andδ opioid receptor subtype-mediated G protein activation and inhibition of cAMP production, while did not affect the concentration- effect relationship ofμ-agonist 〓-enkephalin in the same signalings.

arrestin 1的表达明显减弱了κ型，δ型阿片受体亚型所介导的G蛋白的激活和腺苷酸环化酶活性的抑制，但是却不影响μ型阿片受体亚型特异性激动剂〓-enkephalin刺激引起的浓度效应曲线。

IMPLICATIONS: Ketamine can be used safely in neurologically impaired patients under conditions of controlled ventilation, coadministration of a {gamma}-aminobutyric acid receptor agonist, and avoidance of nitrous oxide.

氯胺酮可以安全的应用於神经系统损伤的病人，但是要控制呼吸以及联合应用γ-氨基丁酸受体激动剂并且避免使用笑气。

Objective: Cyclooxygenase-2 (COX-2) and peroxisome proliferators-activated receptor-gamma play very important roles in occurrence, progression and prognosis of tumor. But the definite effects and mechanisms of specific COX-2 inhabitor and PPARγagonist on the prevention and cure of pancreatic cancer have not been fully elucidated.

目的：近年来研究表明，环氧化酶-2(cyclooxygenase-2， COX-2)和过氧化物酶体增殖因子活化受体γ在肿瘤发生、发展中起十分重要的作用，但特异性COX-2抑制剂和PPARγ激动剂对胰腺癌的防治作用及其机制尚未十分明了。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。