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That consider condyle, bone caruncle of 5 exemple, cartilage fibrosarcoma of 3 exemple, nerve fibroma of 1 exemple, nerve 1. The symptom after 27 patients operation all has different level improvement, live on average without tumour time is 33.5 months. Incontinent companion meets the patient relieve oneself of S1 of 5 operations reservation or above nerve root pubic feeling is lost, after manager cure function trains, 3 parts restore, 2 conserve without progress; bladder and rectum function obstacle all appear after the 12 patients art of root of S2 above nerve, after training via rehabilitation physiotherapy and function, 10 return to normal basically, 2 patients still are put in the obstacle of be convenient to both of different level. 10 withhold S3 or the patient of above nerve root can conserve constrictor function.

结果术后病理报告示:脊索瘤17例、骨巨细胞瘤5例、软骨肉瘤3例、神经纤维肉瘤1例、神经纤维瘤1例。27例患者手术后症状均有不同程度改善,平均无瘤生存时间为33.5月。5例手术保留S1或以上神经根的患者大小便失禁伴会阴部感觉丧失,经理疗功能练习后,3例部分恢复,2例无进展;保全S2以上神经根的12例患者术后均出现膀胱及直肠功能障碍,经康复理疗和功能练习后,10例基本恢复正常,2例患者仍存在不同程度的两便障碍。10例保留S3或以上神经根的患者能保全括约肌功能。

objective: searching for the treatment which prevents the recurrence of the urinary bladder carcinoma after excision.method:according to the consequence of sensitive test ,we poured chemical medicine into artery before and after the operation ,injected mitomycin c into the tela submucosa after the excision of carcinoma during the operation and pour medicine into bladder regularly after operation.result:in all the 65 specimen group,60 got following investigation more than 3 years,the rate was 92.3%.and 4 recured in 19,27,37,43 months after operation.the rate of recurrence was 6.7%.

作者单位:(1。山东省青岛市中心医院,山东青岛 266042 2。山东省青岛市肿瘤医院,山东青岛 266042)目的:探讨膀胱癌切除术后预防肿瘤复发的治疗方案。方法:依据抗癌药物敏感试验结果,在手术前后进行动脉灌注化疗,术中切除肿瘤后于膀胱粘膜下注射丝裂霉素c和术后定期膀胱内灌注。

RESULTS: Of the 44 patients, 25 received adjuvant chemotherapy after operation; 1 received operation alone; 18 received induction chemotherapy. Of the 18 patients, 7 received tumor resection after chemotherapy; 2 patients with primary mediastinal chorioepithelioma with multiple metastases received radiotherapy on residual disease after chemotherapy; 1 patient with postoperative abdominal metastasis and 1 with postoperative lung metastasis achieved complete remission after chemotherapy; 1 patient with mediastinal sinus tumor achieved partial remission after chemotherapy; 6 had poor response to chemotherapy and died of disease progression.

结果:44例患者中,25例行术后辅助化疗;1例单纯手术;18例行诱导化疗,其中7例患者化疗后肿瘤缩小行手术切除,2例原发纵隔绒癌伴多发转移患者化疗后行残留病灶放疗,1例术后腹腔转移和1例术后肺转移患者化疗后获得完全缓解,1例原发纵隔内胚窦瘤化疗后部分缓解,未做进一步治疗,6例患者化疗无效进展死亡。

Hours after infusion, the radioactivity accumulation appeared in lung, and it revealed that the infused cells distributed mainly in lung, and some appeared in liver, spleen, kidney and bladder. 6 hours after infusion, the radioactivity in lung diminished compared with that at 3 hours after infusion, and bilateral kidneys imagine appeared intensively. 9 hours after infusion, the radioactivity in lung appeared reduced significantly than that at 3 hours after infusion, and liver imagined increasedly, intestine tract imagine appeared in several rats.

本研究中,静脉移植MSCs后3h,肺脏放射性浓集,移植细胞主要分布在双侧肺部,肝脏、脾脏、肾脏和膀胱分布较少;移植6h后,肺脏放射性较移植3h时减弱,双侧肾脏显像明显增强;移植9h后,肺脏放射性较移植3h时明显减弱,肝脏显像增强,个别大鼠肠道出现显像;移植18h后,此时肺脏显像明显稀疏,肝脏和脾脏显像显著加强。

The results were as follows the change of vitamin C content was a "trial apex"-shape curve, higher in young fruit,incrustation and maturation stages, lower in other periods; the total acid content was the highest in young fruit, after that, it decreased rapidly, maintained lower level, and reached lowest when the fruit matured; the total content of soluble sugar inosculated with the fruit development, it was high when the fruit development was quick, and low when the fruit development was slow; before 59 d after anthesis, the reducing sugar content was high in the total content of soluble sugar and after that ,the nonreducing sugar content was high; before 45 d after anthesis, free amino acid content was obviously correlated with protein content, and they inosculated with the fruit development;4559 d after anthesis, free amino acid content increased quickly, and protein content decreased gradually, this was also the most shaping period of the embryo and endosperm.

结果表明,Vc含量呈&三峰&型曲线,幼果时、硬核后和成熟时较高,其他时期较低;有机酸含量以幼果期最高,以后迅速下降并维持较低水平,果实成熟时含量最低;可溶性总糖含量与果实发育状况基本相吻合,果实发育速度快时含量较高,慢时较低;在谢花后59 d以前,可溶性糖以还原糖为主,之后以非还原糖为主;游离氨基酸和蛋白质含量,在谢花后45 d以前两者呈高度相关,且与果实生长速度相吻合,谢花后4559 d是胚和胚乳的主要形成期,此期游离氨基酸含量迅速增加,蛋白质含量持续下降。西北林学院学报21卷第5期张传来等金光杏梅果实发育期间主要营养成分动态变化研究

Results:Out of the nine tuberculose patients,six healed after second operation,one sinus formation,two died.Out of the two disruption of wound,one was re-sutured and healed,the other healed after a long term of dressing changing.Seven infectious incision were controlled within one month.Out of the nine cerebrospinal fluid fistulae,eight were cured conservatively,only one spinal meninges was repaired.One epidural hematoma was cleared and made a good healing.Out of the two mold infection,one was cured after focal clearing,the other developed to chronic recurrent sinusitis.Four patients with sore healed after decompression.The other eight patients (four by hemostasis narcotic,two by liquefied fat,two by dermal allergic papular eczema) had good healing after intra-red therapy.

结果:9例结核患者再次手术后6例愈合,1例窦道形成,2例死亡;切口裂开2例中1例经切口再缝合愈合良好,另1例经10个月长期换药切口愈合;7例切口感染者均在1个月内控制感染;9例脑脊液漏,其中8例经保守治疗愈合,1例行脑脊膜再次修补术;1例硬膜外血肿清除后愈合良好;霉菌感染2例,其中1例经病灶清除后切口愈合,另1例演变成复发性窦道炎;4例压疮去除压迫后溃疡愈合;另外8例切口延迟愈合者中止血水引起者4例,脂肪液化2例,皮肤过敏2例,均经红外线照射后切口愈合。

In Wistar rats, latent period of a-wave in scotopic rod response after 1-week transplantation was shorten (P.05); and latent period of a-wave in scotopic rod response after 2-week transplantation was prolonged (P.05); while latent period of b-wave in scotopic maximum response after 1-week transplantation was shorten (P.05). In RCS rats, amplitude of a-wave in scotopic rod response and photopic response after 4-week transplantation was increased (PO.05); while latent period of a-wave in scotopic rod response after 4-week transplantation was shorten (PO.05).Conclusion 1. At the age of 3 months, photoreceptors of the RCS rat degenerated completely, which leaded to the reduction of amplitudes of a-wave and b-wave.

Wstar大鼠术后1周的暗适应视杆反应,a波潜伏期缩短o叼。05);术后2周的暗适应视杆反应,a波潜伏期延长o功刀5):术后1周的暗适应最大反应,b波潜伏期缩短o功刀5卜*CS大鼠术后4周的暗适应视杆反应和明适应反应,a波振幅增大o功刀匀;术后4周的暗适应视杆反应,a波潜伏期缩短o<0卜结论1、RCS大鼠在3月龄时感光细胞变性死亡,导致FERG的a、b波振幅明显降低;视网膜下腔仍存在感光细胞外节盘膜碎屑,外丛状层缺乏感光细胞的突触末端,同时Muler细胞出现反应性胶质纤维增生。

The dynamic changes of the the neuron apoptosis and correlative genes in hippocampus of ACET-groups and twice-ACET-groups suggested that ACET can slower the apoptosis by inhibiting p~(53)and prolong the ascending period of p~(53) in 4 days after the seizure,this effect would weaken after 4 days.ACET may inhibit the descending of Bax,prolong its descending period and then promote its expression,in order to weaken the inhibition of the apoptosis during 4 to 10 days after seizure and then promote the apoptosis during 10 to 14 days after.This effect of ACET can be enhanced after treating again within 7 to 14 days later.

埋线组和二次埋线组大鼠海马神经元凋亡及相关基因表达的动态变化结果提示:埋线治疗在癫痫发作后的早期(4d内)可通过抑制促凋亡基因p~(53)蛋白表达、延缓其达峰值的时程,从而减缓神经元凋亡的发生,此作用在4d后减弱;埋线治疗抑制大鼠海马神经元凋亡的作用在癫痫发作后的中期(4d~10d)减弱,甚至在远期(10d~14d)出现促进凋亡的作用,可能是通过抑制Bax蛋白表达的下降、延长其降至低峰值的时程,促进Bax蛋白表达的回升的结果;在中远期(7d~14d)内予二次埋线治疗对该效应有续效叠加的作用。

Results: There were different degree of distending pain and sensory disability presented in the injected position after injection. The numbness disappeared after 1 to 3 month. Return visit examination after 1 month showed that pain of 52 cases disappeared and 9 cases remitted, remission rate was 97%. 57 cases were followed-up surveyed after 6 months, 4 cases recurred and recurrence rate was 7%. 50 cases were followed-up surveyed after 3 years, 11 cases recurred and recurrence rate was 22%.

结果:注射后患者均有局部胀痛,注射区均有不同程度感觉障碍,局部感觉迟钝。1~3个月后麻木感消失。1个月后复诊,52例疼痛消失,9例疼痛缓解,有效率97%,6个月后随访57例,症状复发4例,复发率7%,3年对50例进行随访,疼痛复发11例,复发率22%。

METHODS: 40 cases were classified stage IV with lumen obstruction after they failed all other treatment regimens. PDT was performed witn 630nm light delivered through cylinder diffusing tip quartz fibers passed through the biopsy channel of a flexible endoscope 48h after intravenous injection of the photosensitizer photofrin. PDT endoscopy was repeated and necrotic tissue was mechanically removed and, if necessary, that site or other new sites were treated after 48 hours. Two days after this another endoscopy was performed and the necrotic tissue was mechanically removed. Endoscopy was repeated one month after PDT and periodically thereafter as needed to re-treat symptomatic residual tumor.

40例肿瘤患者均属于IV期,所有患者都经过化疗、放疗或其他方法治疗无法解除腔道梗阻或不完全梗阻,部分完全梗阻患者结合其他治疗手段解除梗阻,光敏剂为photofrin,按2mg/kg体重静脉滴注,48小时后经内镜导入光导纤维给以630nm(DIOMED半导体激光治疗机)的激光照射,2天后经内镜清除坏死组织并对原有病灶和新发现病灶给以复照,之后根据具体情况给患者的病灶部位清除坏死组织。

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