查询词典 adeno-acanthoma

Objective: In order to investigate whether the recombinant adeno-associated virus -mediated foreign genes, LacZ/hVEGF, could pass the blood brain barrier by intra-carotid artery delivery or not and to investigate whether the foreign genes could be expressed in vivo in ischemic brain of the focal embolic stroke rats or not, a high titer and completely adenovirus free recombinant adeno-associated virus vector was constructed and studied.

目的：为了检测腺相关病毒载体携带的人类血管内皮因子基因能否通过血脑屏障及能否在脑组织中表达其基因产物，我们构建了一种新型、高滴度、无腺病毒污染的rAAV携带的报告基因和hVEGF基因分别经颈动脉对自体血栓局部脑卒中大鼠进行了研究。

Methods The viral particles of recombinant adeno-associated viral vector 2-IRES-EGFP/MnSOD(rAAV2-IRES-EGFP/MnSOD) were injected into the perilymph through the round window membrane on the 6th week.To observe the feasibility of MnSOD gene therapy for protecting the cochlear function with the methods of Westernblot, ApopTag peroxidase apoptosis detection, MnSOD activity detection and effect on hearing.

方法在半乳糖注射的第6周(注射氨基糖甙类抗生素之前2周)将rAAV2-IRES- EGFP/MnSOD病毒液经圆窗膜注入拟老化大鼠的耳蜗外淋巴，通过免疫组化(ApopTag过氧化物酶凋亡检测)、Westernblot及MnSOD活性检测的方法观察MnSOD基因在对抗内耳氧化应激损伤中的干预性保护作用。

Objective To demonstrate the feasibility of thyroid gene therapy by using a adeno-associated virus vector to deliver the sodium/iodide symporter gene into the thyroid tumor cells.

目的探讨钠碘同向转运体基因介导的甲状腺癌基因治疗的可行性。

Methods Using recombinant adeno viruses,we expressed the B7.1 gene in murine breast tumor cell line EMF6 and a subline previously transfected with retrovirus vector XdF containing IL-2-TNFα fusion gene.

在小鼠乳腺癌细胞系EMF6和一个已被含有IL-2和TNFα融合基因的逆转录病毒载体XdF转染的EMF6亚系(T2-EMF6)中表达B7.1基因。

In this trial, which began in March 2006, researchers injected a dystrophin gene compound called Biostrophin, which was developed with MDA support at Asklepios Biopharmaceutical in Chapel Hill, N.C., into the biceps muscles of boys with DMD.Biostrophin is a combination of miniaturized dystrophin genes and adeno-associated viral shells that home to muscle fibers.

这次试验始于2006年3月，研究人员将名为biostrophin的抗肌营养不良蛋白基因化合物（在俄亥俄州哥伦比亚儿童医院同肌肉营养失调协会的支持下，由Asklepios生物医药公司制造）注入了到DMD男孩们的二头肌中。biostrophin是由微型肌营养不良蛋白基因和来自肌纤维的腺相关病毒壳合成的。

Adeno-associated virus;P27;MG-63 cell;Pien Tze Huang; osteosarcoma

腺相关病毒； P27 ； MG-63细胞；片仔癀；骨肉瘤

Results The concentration of Chlorogenic acid was 0.05mg/ml, 0.1mg/ml, 0.4mg/ml, 0.8mg/ml respectively, it can respectively inhibit respiratory syncytia virus, Coxsackie B3 virus, adeno-associated 7 virus, adeno-associated 3 virus and Coxsackie B5 virus.

结果 氯原酸浓度分别为0.05mg/ml、0.1mg/ml、0.4mg/ml、0.8mg/ml时，可分别体外抑制合胞病毒、柯萨奇B3、腺病毒7型、腺病毒3型和柯萨奇B5型。

Results The concentration of Chlorogenic acid was 0.05mg/ml, 0.1 mg/ml,0.4mg/ml,0.8mg/ml respectively,it can respectively inhibit respiratory syncytia virus,Coxsackie B 3 virus,adeno associated 7 virus,adeno associated 3 virus and Coxsackie B 5 vi...

结果 氯原酸浓度分别为 0 。0 5mg/ml、0 。1mg/ml、0 。4mg/ml、0 。8mg/ml时，可分别体外抑制合胞病毒、柯萨奇B3、腺病毒 7型、腺病毒 3型和柯萨奇B5型。结论氯原酸对常见呼吸道病毒有较强的抑制作用

The genome of avian adeno-associated virus was cloned for construction of gene transfer vectors. AAAV was propagated in special pathogen-free chicken embryo using the chicken embryo lethal orphan virus as the helper virus. The double-stranded genomic DNA was extracted from precipitated AAAV viron and cloned into pCR 2.1 vector.

为了克隆禽腺联病毒(Avian adeno-associated virus， AAAV)全基因组用于构建基因转移载体研究，以鸡胚致死孤儿病毒作为辅助病毒与AAAV共接种SPF鸡胚进行AAAV的增殖，将AAAV约4.7 kb双链基因组DNA与pCR2.1载体连接，构建了含AAAV全基因组的重组质粒pAAAV并进行了测序。

RESULTS The positive rate of P-gp170expression in cervi-cal cancer pre-radiotherapy was58%（22/38）.Among them,the positive expression rates were10/18（56%）,6/10,4/6and2/4in keratinizing,nonkeratinizing squamous-cell carci-noma,adenocarcinoma and adeno-squamous-cell carcinoma respectively.The positive rate of post-radiotherapy was90%（34/38）and among them,the positive expression rates were16/18（89%）,8/10,6/6and4/4in keratinizing,nonkera-tinizing squamous-cell carcinoma,adenocarcinoma and adeno-squamous-cell carcinoma respectively.

结果 宫颈癌组织P-gp170阳性表达在放疗前为58%（22/38），其中角化型、非角化型鳞癌、腺癌及腺鳞癌分别为10/18（56%），6/10，4/6，2/4例；放疗后其P-gp170阳性表达为90%（34/38），其中角化型、非角化型鳞癌、腺癌及腺鳞癌分别为16/18（89%），8/10，6/6，4/4例，P-gp170表达阳性强度较放疗前亦呈增高趋势。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。