查询词典 acute

Results among the 104 primary acute leukemia patients, the number of patients with t lymphocyte leukemia,b lymphocyte leukemia,acute myeloblastic leukemia,mixed phenotype acute leukemia and umclassified leukemia were 4(3.8％),38(36.5％),58(55.8％),2(1.9％),and 2(1.9％),respectively.conclusion detecting immune marker on leukemic cell by abc-ap two step immune method is very simple which can be finished with a light microscope,and it can provide a reliable basis for the diagnosis and classification of leukemia and even the targeting therapy for leukemia.

结果 104例初发急性白血病中，t淋巴细胞白血病4例(3.8％)，b淋巴细胞白血病38例(36.5％)，急性髓细胞白血病58例(55.8％)，急性混合性白血病2例(1.9％)，未行明确分类的2例(1.9％)。结论 abc-ap免疫二步法检测白血病细胞免疫标记方法简单，只须普通光学显微镜就能开展实验，可为白血病的诊断、分型、分类乃至白血病靶向治疗提供可靠依据。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

vWF and Ps are involved in acute cerebral infarction, hepertension and diabetes mellitus,The result suggested that the contents of vWF and Ps play an important role in the development of acute cerebral infarction, The study of vWF and Ps in molecular biology is important in outbreaking mechanism of acute cerebral infarction, making a diagnose and giving treatment.

急性脑梗死、高血压、糖尿病患者vWF、Ps表达上调，说明vWF、Ps参与了急性脑梗死、高血压、糖尿病的病理过程，因此，vWF、Ps的增高，在急性脑梗死的发生和发展过程中起着重要作用。

This review briefed the relation between apoptosis and acute pancreatitis, investigated the influence of apoptosis on acute pancreatitic organ damage, and analyzed the relation between apoptosis and inflammatory cytokines, oxidative stress, endoplasmic reticulum stress, Notch factor, aiming at revealing the mechanism of apoptosis in acute pancreatitis.

本文简述细胞凋亡与急性胰腺炎之间的关系，探讨细胞凋亡对急性胰腺炎器官损伤的影响，分析细胞凋亡与炎症因子、氧化应激、内质网应激、Notch因子的关系，从而揭示急性胰腺炎细胞凋亡的发生机制。

The clinical and CT datas were analyzed retrospectively.Results Of 45 cases,acute appendicitis in 9 cases;acute appendicitis accompanied with periappendicitis in 14,acute appendicibis accompanied with perforation in 5,appendiceal abscess in 13 and inflammatory mass in 4,were diagnosed by CT.

结果 45例中CT诊断为急性阑尾炎可能1例（2.22%）；急性阑尾炎8例（17.78%）；急性阑尾炎并阑尾周围炎14例（31.11%）；急性阑尾炎并穿孔5例（11.11%）；阑尾脓肿13例（28.89%）；阑尾炎性肿块4例（8.89%）。

As a new diagnostic method, DTI technology should be a routine examination for cerebrovascular diseases.3 DTI sequence should be added when the patient with cerebral ischemia has been examinated by routine MRI and found LA or cerebral infarction on acute stage in doubt. DTI can find hyper-acute and acute cerebral infarction immediately in order to treat the illness in time.4 DTI technology can reflect the mini-alter of alba formation pericerebral infarction with non-invasion in vivo. It can also appraise the degree of cerebral infarction and anticipate the result.

应作为脑血管病影像学常规检查。3对于临床上有脑缺血表现的患者，其常规MRI检查仅发现有脑白质疏松或怀疑有急性期脑梗死，应该加做DTI序列以便及时发现并治疗疾病。4 DTI可在活体无创性的反映脑梗死灶周脑白质结构的微细改变及评估缺血性病变损伤的严重程度和预测脑梗死结果。

objective to study the changes of t-pa and t-pa inhibitorduring the acute stage of cor pulmonale.methods to measure the plasmatic activity of t-pa and pai by chrom-substrate in60cases of cor pulmonale,compared with the corresponding index of55cases in the control group.results pai was significantly higher in acute stage than in remission stage of corpulmonale,and t-pa was lower in remission stage than in acute stage.the difference was significant（p.01）.conclusion the unbalance between t-pa and pai can promote the formation of micro-thrombus and further exacerbate high pulmonary pressure.

目的 探讨血浆组织型纤溶酶原激活物及t-pa抑制物在肺心病急性加重期的变化。方法用发色底物法测定60例肺心病急性加重期的血浆t-pa及pai的活性，并与对照组55例肺心病缓解期的相应指标作比较。结果肺心病急性加重期患者pai显著高于肺心病缓解期，而t-pa低于肺心病缓解期，其差异具有非常显著性（p.01）。结论 t-pa及pai关系失衡，有助于动脉内微血栓形成，促进或加重肺动脉高压的形成。

Results One patient was complicated with prilnary non-function of the transplanted liver after liver transplantation;Five patients completed regained consciousness within 48 hours after operation; One patient complicated with acute renal failure;One patient complicated with acute liver cell rejection postoperatively and reversed after treatment;One male patient complicated with serious stomatocace;Two patients complicated with acute respiratory distress syndrome,underwent tracheotomy.

结果行急诊肝脏移植治疗6例，术后1例并发原发性移植肝无功能，5例患者于48h内苏腥。1例男性患者术后并发急性肾功能衰竭，1例患者术后发生排斥反应，经治疗后逆转。1例男性患者并发口腔严重溃疡。2例并发急性呼吸窘迫综合征，行气管切开。

In recent years, the flower of Trollius chinensis has been used clinically on acute tonsillitis, upper respiratory tract infection, pharyngitis, acute enteritis and acute bronchitis and showed remarkable effect.

在民间用药基础上，结合现代药理研究，金莲花作为一较好的抗菌药物应用已被肯定，但目前国内外对于其药效物质基础及质量标准的系统研究尚属空白。

In infarction patients group,DTI can early detect some small infarction lesions in white matter. With the pathophysiological evolution of the disease, FA and ADCAV changes regularly. In hyper-acute stroke, FA of lesions have no consistent change, appreciably elevated or decreased. In acute, sub-acute and chronic stages of cerebral infarction, FA of lesions unrecovered declined.

在脑梗死患组DTI能早期发现较小的白质内梗死灶，脑梗死后脑组织FA值、ADCAV值随病理生理演变呈一定规律性变化，病侧FA值在超急性期较对侧无一致性变化，可轻度升高或者轻度降低，随后(急性期、亚急性期、慢性期)呈不可复性减低趋势。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。