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Acute myeloblastic leukemia ; children ; high-dose Ara-C ; therapeutic effect ; drug concentration

髓系白血病;儿童;大剂量阿糖胞苷;疗效;药物浓度

Methods The expression and change of TF and TFPI were detected in the peripheral venous blood samples from 20 normal controls, and 78 patients with haematological malignancies—34 patients with acute leukemia, 12 with chronic myeloblastic leukemia, 12 with non-Hodgkin lymphoma, 7 with multiple myeloma, 6 with myeloproliferative disorders, and 7 with myelodysplastic syndrome, by enzyme linked immunosorbent assay. After that, the correlation of TF and TFPI were analyzed.

选择正常对照组20例,恶性血液病组78例,其中急性白血病34例,慢性粒细胞白血病12例,非霍奇金氏淋巴瘤12例,多发性骨髓瘤7例,骨髓增殖性疾病6例;骨髓增生异常综合征7例。

Methods Magnetic resonance imagings of pelvis and femur were performed on 28 adult patients first diagnosed as acute granulocytic leukemia and 16 diagnosed as chronic myeloblastic leukemia based on morphology,immunophenotype and cytogenetic analysis. Twenty age-matched healthy volunteers were selected as controls. Results MRI of bone marrow in all patients were obviously different from those in controls.

方法搜集经细胞形态学、免疫学及遗传学分型综合分析确诊的成人初诊急性粒细胞白血病28例及慢性粒细胞白血病16例,所有患者均行骨盆及股骨中上段MRI检查,选取20名年龄匹配的健康志愿者作为对照组。

Results showed that urokinase at 20U/ml was the optimal concentration used. Fibrinolysis kinetics and plasma plasminogen concentration of 27 normal persons and 27 patients with acute myeloblastic leukemia were detected, a significant difference was observed between the two groups. Repetition test showed that the coefficience of variation was 5.24±1.51%. This method could also be used to detect the concentration of plasma fibrinogen.

结果 初步建立了正常人纤溶动力学分析参数,确定了20U/ml尿激酶为最适试验浓度,检测22例正常人,27例急性髓细胞白血病患者纤溶动力学及纤溶酶原含量,显示患病组较正常组差异有显著意义(P.05, P.01),重复性试验显示该方法的变异系数为(5.42±1.51)%,并可同步测定血浆纤维蛋白原浓度。

MDS is a heterogeneous and common group of clonal hematological disorders characterized by a multi-step process which begins with a somatic mutation in the pluripotential stem cell, and a high rate of tranformation into acute myeloblastic leukemia.

MDS是造血干细胞恶性克隆性疾病,呈现多系改变、多阶段进展两大特征,最终往往发展成AML。

ABSTRACT]ObjectiveTo study the expression of telomerase activity in patients with acute myelocytic leukemia and its clinical significance.

摘要]目的研究急性髓细胞白血病的端粒酶活性表达情况,探讨端粒酶活性检测对AML的临床意义。

Objective: To study the change and significance of sICAM-1 and sVCAM-1 in patients with acute myelocytic leukemia.

目的:探讨急性髓细胞白血病患者血清细胞间黏附分子-1(ICAM-1, CD54)和血管细胞黏附分子-1(VCAM-1, CD106)的水平变化及其临床应用。

Objective To study the biological and clinical characteristics in the eldly with acute myelocytic leukemia.

目的 研究老年CD7抗原阳性急性髓性白血病(CD7+AML)的临床生物学特征。

ABSTRACT] Objective: To study the change and significance of sICAM1 and sVCAM 1 in patients with acute myelocytic leukemia.

作者:作者:吴凯,谢朝阳作者单位:1。广东省深圳市罗湖区中医院,广东深圳 518001;2。

Leukemia ; myelocytic ; acute ; interleukin 1; lymphocyte function associated antigen 1; macrophage 1 antigen

白血病;粒细胞;急性;白细胞介素1;淋巴细胞功能相关抗原1;巨噬细胞1抗原

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推荐网络例句

Nowadays, most of research are to build a transmutative Petri Nets through adding controlling place sets, controlling arc sets and controlling policy to the basic Petri Nets, while the Controlled Petri Nets could be used to argue many controlling theory problems conveniently and to induce many logically and physically supervisory and solve the Event Feedback Controlling Problems and State Feedback Controlling Problem in DEDS supervisory theory.

目前大多数的研究表现为在变形后的受控Petri网基础上,利用各种方法求得各种逻辑型、结构型控制器,解决DEDS监控理论中的事件反馈控制问题与状态反馈控制问题。

On one hand, there are discussions with the works council and union about extension of short time working up to the end of September.

一方面,有讨论,工程理事会和联盟关于延长工作时间短至9月底。

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