查询词典 activation radioactivation

The results of this reseach showed that administration of SF intracolonically had protective effect on the colon injury in the rat model of colitis induced by acetic acid enema, which was probably due to the mechanism of antioxidation, inhibition ofarachidonic acid metabolis and platelets activation, administration of SF intracolonically also showed protective effect on the colon injury in the rat model of colitis induced by trinitrobenzene sulfonic acid and ethanol, which was probably due to antioxidation and inhibition of macrophages activation.

实验研究表明，大鼠分别经乙酸、TNBS和乙醇处理后均出现典型的结肠炎症状，给药后分别评价结肠粘膜损伤指标、结肠组织病理变化，检测结肠组织炎症指标、结肠组织氧化损伤指标及主要炎性细胞因子改变；实验结果：阿魏酸钠对大鼠乙酸性结肠炎结肠粘膜损伤具有缓解保护作用，其机制可能与直接抑制炎症结肠粘膜花生四烯酸代谢过度，抑制血小板活化，清除大量氧自由基有关；阿魏酸钠对大鼠TNBS性结肠炎粘膜免疫损伤亦具有缓解保护作用，其机制可能与抗氧化，抑制结肠巨噬细胞活化有关。

Interestingly, HG-induced Janus kinase 2 (JAK2)-signal transducers and activators of transcription 1 (STAT1) activation but not STAT3 or STAT5 activation at 30 min were blocked by NO donors and PKG activator.

有趣的是在刺激30分钟后，高糖会明显诱发JAK2与STAT1的活化，但STAT3与STAT5的活化则不受影响。在加入NO供给者及PKG活化剂后均可有效抑制上述高糖的效应。

To investigate the function of Nogo-A in neurons, human embryonic kidney cell line 293FT was used as a model, along with the pathway profiling reporter system to check the involvement of Nogo-A in regulating the intracellular signaling pathway. It was found that over-expression of Nogo-A could activate NF-κB signaling specifically, then followed by using different Nogo-A alternative splicing isoforms and a serial of truncations, it was confirmed that the activation of NF-κB by Nogo-A relied on its N-terminal proline rich domain. Furthermore, by co-expressing the dominant negative mutants of some NF-κB pathway associated proteins, it revealed that the IκBα,TRAF6, Rac/Cdc42 were involved in Nogo-A inducing activation of NF-κB.

为探讨神经元内Nogo-A的功能，以HEK293FT细胞为模型，利用信号途径报告基因系统筛选过表达Nogo-A对多种信号途径的调控作用，发现过表达Nogo-A能特异激活NF-κB信号，利用不同的Nogo-A剪接体和截断体形式研究，证明Nogo-A激活NF-κB信号依赖于其氨基端的proline rich结构域，进一步使用NF-κB信号途径相关分子显性突变体揭示IκBα、TRAF6、 Rac/Cdc42 参与Nogo-A激活NF-κB信号。

To investigate the function of Nogo-A in neurons, human embryonic kidney cell line 293FT was used as a model, along with the pathway profiling reporter system to check the involvement of Nogo-A in regulating the intracellular signaling pathway. It was found that over-expression of Nogo-A could activate NF-KB signaling specifically, then followed by using different Nogo-A alternative splicing isoforms and a serial of truncations, it was confirmed that the activation of NF-kB by Nogo-A relied on its N-terminal proline rich domain. Furthermore, by co-expressing the dominant negative mutants of some NF-kB pathway associated proteins, it revealed that the IkBα,TRAF6, Rac/Cdc42 were involved in Nogo-A inducing activation of NF-kB.

为探讨神经元内Nogo-A的功能，以HEK293FT细胞为模型，利用信号途径报告基因系统筛选过表达Nogo-A对多种信号途径的调控作用，发现过表达Nogo-A能特异激活NF-kB信号，利用不同的Nogo-A剪接体和截断体形式研究，证明Nogo-A激活NF-kB信号依赖于其氨基端的proline rich结构域，进一步使用NF-KB信号途径相关分子显性突变体揭示IkBα、TRAF6、Rac/Cdc42参与Nogo-A激活NF-kB信号。

Early production of activated carbon materials for the timber, hard shell or animal bones, and later the main use of coal, by dry distillation, activated carbon after activation production methods are:① steam, gas activation.

早期生产活性炭的原料为木材、硬果壳或兽骨，后来主要采用煤，经干馏、活化处理后得到活性碳生产方法有：①蒸汽、气体活化法。

Once the temperature of the environment exceeds the critical explosion temperature, the delayed-action time will shorten along with the temperature of the environment ascending;(2) The thermal decomposition reactivity activation energy and correlative parameters of the emulsion explosive matrix and corresponding mixture of emulison explosive with combustible oil solvent were obtained by iron-plate experiment, thereinto, the activation energy of the emulsion explosive matrix is 163.3kJ/mol.

一旦环境温度超过临界爆炸温度，随环境温度的升高，爆炸延滞期将变短；(2)通过铁板实验获得了乳化炸药基质及其与有机溶剂混合物的活化能和相关参数，其中乳化炸药基质的活化能为163.3kJ/mol。

These catalytic reactions follow the bifunctional mechanism of Lewis acid activation and metal hydroxide activation.

催化反应遵循Lewis酸活化和金属羟基活化的双功能机理。

It was found that the activation energy deduced from the modified Arrhenius equation is a constant independent of temperature.

由修正后的Arrhenius公式计算得到的电导活化能是一个与温度无关的常数。

At present, aberrant WIF-1 activation is normal in several human tumors.

目前在人类多种肿瘤的研究发现WIF-1表达异常。

Evidences show that excitotoxcities of excited amino acid and free radical, Ca2+ overload, environmental alteration of neurons, mitochondrial dysfunction and activation of some apoptotic genes may be involved in it.

缺血性脑卒中确切的神经元凋亡机制尚不清楚，目前认为可能与兴奋性氨基酸、Ca2+超载、自由基的毒性作用、神经元生存环境的改变、线粒体功能障碍及凋亡调控基因的激活等因素有关。

More direct, directer ; most direct, directest

径直的，笔直的

Do you know how to use a chain saw?

你知道如何使用链锯吗？