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The results of bioassay indicated: 1 The new compound (compound 6) and other three compounds (compound 1, 2 and 5) showed strong anti-HIV activity (EC50.064μg/ml), compound 3 and 4 showed less activity (EC50=6.18μg/ml and 12.85μg/ml respectively); Compound 5 and 6 showed weak cytotoxicity, and compound 1-4 showed moderate cytotoxicity; 2 Compound 5 and 6 were activated to all the four tested microbial; Compound 1, 2 and 13 were activated to all the three tested bacterial, but were unactivated to the tested fungi, Penicillium avellaneumUC-4376; One of the test bacterial, Staphylococcus aurues, seemed to be sensitive to all the eleven triterpenoids.

新化合物(化合物6)和化合物1、2、5具有强烈的体外抗HIV活性,其EC50值均小于0.064μg/ml,化合物3和4也具有抗HIV活性,但活性相对较弱,EC50值分别为6.18μg/ml和12.85μg/ml;化合物1-6都具有一定的细胞毒性,且化合物5和6的细胞毒性明显弱于化合物1-4的。 2)新化合物(化合物6)和化合物5对所有四种试验菌都有一定的活性;化合物1 、2和13对三种细菌均有一定的活性,但对真菌橙色青霉UC-4367(Penicillium avellaneum UC-4376)无活性;金黄色葡萄球菌对所有11个三萜都较为敏感。

Compared with the unactivated P polyelectrolyte film, the activated form P/PMMA polyelectrolyte film obtained by adopting the technology of the invention has better absorbency, room-temperature conductivity, electrochemical stability and the interface stability of electrolyte and lithium electrode; the performance of a lithium secondary battery prepared by using activated electrolyte is obviously better than the performance of the lithium secondary battery prepared by using the unactivated polyelectrolyte; the invention has simple technology, short reaction time, and convenient and easy condition for technologized production.

采用本发明技术获得的活化型P/PMMA聚合物电解质薄膜相比未活化的P聚合物电解质膜,有更好的吸液性和室温电导率,更好的电化学稳定性及电解质和锂电极的界面稳定性;用活化后的电解质制备的锂二次电池性能明显好于未活化聚合物电解质制备的锂二次电池;本发明工艺简单,反应时间短,为工艺化生产提供了简便易行的条件。

This research was on sequencing batch reactor activated sludge system, using 2,6-dichlorophenol as uncoupler with the concentration of 20,using Cu~(2+) with the concentration of 1,adding into the SBR activated sludge system.

采用间歇式活性污泥培养装置,以2,6-二氯苯酚作为解偶联剂,浓度为20 mg/L,Cu2+浓度为1 mg/L,加入到间歇式活性污泥反应器中。

This method can reduce sludge production radically and virtually. The effectiveness of eight metabolic uncouplers in reducing sludge production from activated sludge process were compared to screen effective, cheap and non-toxic available uncoupling chemicals and determined the long-term uncoupler effects of 3, 3', 4', 5-tetrachlorosalicylanilide in activated sludge batch cultures.

首先比较筛选了对污泥的减量化效果好、价廉、无毒的化学解偶联剂;在此基础上,研究了添加3,3′,4′,5-四氯水杨酰苯胺的分批活性污泥工艺的剩余污泥减量化效果,以及对工艺运行效能和污泥性能的影响;着重进行了添加TCS的活性污泥工艺、好氧—沉淀—缺氧工艺、添加TCS的OSA联合工艺的连续运行试验研究。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养,通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆;以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达,了解不同治疗阶段VEGF及其受体的表达状况,并结合临床指标进行分析,明确VEGF及其受体在白血病发生过程中的作用;流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析,初步阐明难治性白血病抗凋亡形成的原因;蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达,初步了解难治性白血病形成的分子生物学机制。

A temperature rise of 69K will occur during adiabatic filling of methane from activated carbon between pressure levels of 1 and 36atm if the volumetrically adsorption capacity of methane on activated carbon was 140V/V.

在本实验范围内制备高比表面积活性炭的最佳条件是:活化时间60min,活化温度770℃,碱炭比5∶1,原料粒度为100~450μm的辽宁盘锦焦,制得的高比表面积活性炭的比表面积达到3730m〓/g。

Results: 1. The value of all experimental indexes decreased significantly after heat stress, and reached the lowest at the time 2-8 hours after heat stress. This indicates that the immunity of the mice is damaged to the largest extent at 2-8 hours after heat stress. 2. L-arginine supplementation with appropriate dose could remit the acute atrophying of thymus and spleen tissue caused by heat stress. 3. After L-arginine supplementation with appropriate dose, the lymphocyte proliferation, the level of concentration of IL-2 and * expression of IL-2R raised in the group with room temperature; in the heat stress group the level of three indexs decrease significantly. Furthermore, the decrease of the group given 1 .Smglg.bw L-arginine is the smallest. This result indicates that the concentration of 1 .Smglg.bw L-arginine supplementation could remit the depressment of the immunity caused by heat stress. 4. The [Ca2~] in activated thymocytes of the group with L-arginine -2- supplementation is significantly higher than that of the group with water supplementation. This indicates that L-arginine supplementation could protect thymoeytes of mouse under heat stress. We also found that the fluorescence intensity of [Ca2~] in activated thymocytes of the group given 1 .Smglg.bw L-arginine is the highest.

结果:1、热应激后小鼠的各项免疫指标均有显著性下降,其中在2.8小时降到最低,提示在这个时间段小鼠的免疫功能受到最大损害;2、适量补充精氨酸有助于缓解热应激导致小鼠胸腺和脾脏的急性萎缩;3、常温组,补充适量精氨酸后小鼠淋巴细胞增殖活性、IL-2的浓度及IL-2R的表达均有显著性上升,而热应激后三指标均显著降低,其中在精氨酸给予浓度为1.5mg/g.bw时三指标的降低程度最少,提示该浓度可最大程度缓解热应激对小鼠免疫功能的抑制;4、补充精氨酸组的活化胸腺细胞[Ca~(2+)]较给水组有显著性上升,说明精氨酸对热应激小鼠胸腺细胞具有保护作用,并发现在精氨酸给予浓度为1.5mg/g.bw时活化胸腺细胞的胞浆钙离子荧光强度达到最大;5、热应激后小鼠血清NO的浓度均有不同程度的上升,补充精氨酸后血清NO上升更加明显,但并非随精氨酸给予浓度的增加而增加。

000 Mg/L phenol and 200 mg/L 4-cp were biodegraded within 51 h by cells immobilized in activated carbon integrated hollow fiber membranes, while it took about 88 h without activated carbon.

在膜的制作过程中添加了一定量的活性炭后,发现膜对苯酚和四氯苯酚的吸附能力增强,同时结构上更疏松,对四氯苯酚的降解效率得到了提高。

METHODS: We randomized 42 healthy parturients in early laborto receive 0.1% ropivacaine + fentanyl 2 g/mL eithervia PCEA+BCI (n = 21,bolus 5 mL, lockout 10 min, basal infusion5 mL/h) or via PCEA+AMB (n = 21, patient-activated bolus of5 mL, lockout 10 min, basal automated boluses of 5 mL/h [omittedif a patient-activated bolus was successfully administered inthe last 1 h]) after successful induction of combined spinalepidural analgesia.

我们将42名处于早期产程的健康娠妇女在成接受腰硬联合镇痛后,随机分为两组,一组接受 PCEA+BCI (n = 21,单次给药5ml ,锁定时间 10分钟,背景剂量5 mL/h),另一组接受 PCEA+AMB (n = 21,患者自控单次给药5 mL,锁定时间 10 分钟,背景剂量自单次给药5ml/h),两组均给予0.1%的罗哌卡因+太尼2 g/mL 。

This fiber could be carbonized or activated into carbon fiber and activated carbon fiber material with wide use and good capability.

该纤维可进一步炭化或活化加工成用途广泛、性能优良的破纤维和活性破纤维材料。

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The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0,0.4,0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗,测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础,研究二值图像的形态分析算法,探讨最小结构元素的两种基本形态:膨胀和腐蚀;分析了数学形态学复杂算法的基本原理,把数学形态学的部分并行处理理念引入到家实际应用中。

Have a good policy environment, real estate, secondary and tertiary markets can develop more rapidly and improved.

有一个良好的政策环境,房地产,二级和三级市场的发展更加迅速改善。