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In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Cases under title 11 or under the Bankruptcy Act that, from the date of entry of the order for relief or the date of adjudication, as the case may be, antedate the report by more than 10 years.

美国法典第11编项下的案件或破产法项下的案件，自发出救济令或破产宣告之日起，在报告之前超过10年。

He chose such parts, not always for the best, because the role of anti-hero was a challenge and an act of defiance.

他之所以选择这些角色并非总是为了最好，而是因为出演反英雄的角色是一个挑战，一种反抗的行为。

He chose such parts not always for the best because the role of anti-hero was a challenge and an act of defiance.

他之所以选则这些角色并非总是为了最好，而是因为出演反英雄的角色是一个挑战，一种反抗的行为。

The research progress on the formation of ordered molecular assembly in imidazolium ILs, such as liquid crystal, micelle, vesicle, microemulsion was reviewed. ILs can act as solvents, co-solvents, or surfactants to form liquid crystals. They also can be substituted for polar, apolar, or surfactant components in microemulsion to prepare various microemulsion systems ILs-in-oil, oil-in-ILs and bicontinuous B.

咪唑类离子液体可以作为溶剂、助溶剂和表面活性剂形成液晶；离子液体可以分别取代微乳液体系中的极性组分、非极性组分或表面活性剂，形成油包离子液体、离子液体包油和双连续的新型微乳液体系。

Reflection on the unity of apperception demonstrates the fact that an act of synthesis is necessary for the possibility of apperception.

对统觉统一的反思demonstrates了这个事实：'综合的行为'对统觉的可能性老说，是必要的。

Apraxia arises from lesion to the regions associated with preparation and planning for the motor act, specifically the supramarginal gyrus of the parietal lobe, Broca's area, and the SMA.

失用症源自於对运动行为相关连的准备与筹划区域的减退，特别是顶叶布洛卡区域以及补充的运动区域缘上的脑回。

There, for reasons that remain obscure, Theseus left Ariadne behind - an act that is hard to describe as creditable to his reputation.

因为岛上的环境十分的偏僻幽暗，而在路途中塞席尔斯留下了艾瑞妮，而造成他未来辉煌的名声来说，一个非常讽刺的污点之一。

Dr Arkin believes that there is another reason for putting robots into battle, which is that they have the potential to act more humanely than people.

阿金博士相信，让机器人赴死杀场另有缘由，即它们的行为具有比军人更人性化的潜能。

The situation in Armanias was urgent. The Empire had to select their armorer quickly, and once selected, the preferred armorer had to act swiftly and produce the finest armor and weaponry for the Imperial army in Black Marsh.

Armanias的情况非常紧急，帝国必须尽快选择武器制造者，而且一旦确定下来，他们会让制造者立刻为战斗在黑沼泽帝国军队生产出最好的武器和装甲。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷