查询词典 acetylation

OBJECTIVE: To investigate the effects of intrauterine growth retardation caused by malnutrition during pregnancy on the acetylation of histone H3 and expression of histonedeacetylase1(HDAC1) in the hepar of the adult offspring and to explore the relationship between them.

目的：研究孕期营养不良造成的宫内生长受限(intrauterine growth retardation，IUGR)大鼠肝脏中组蛋白H3的乙酰化水平，以及组蛋白去乙酰化酶1 (histonedeacetyl-ases，HDAC1)的表达变化，探讨两者之间的相互联系。

Increased hepatic acetylation of histone H3 in the IUGR offspring might be caused by decreased HDAC1 expression in nuclear protein. This may contribute to the transcription change of some genes in the hepar.

IUGR大鼠肝细胞核中HDAC1蛋白表达降低，引起组蛋白H3的乙酰化水平增高，染色质的表观遗传学变化可能是肝脏某些基因转录调控变化的分子基础。

Aim To prepare lower degree of substituted starch acetate with cassava starch as material, acetic anhydride as acetylation reagent, sodium hydroxide as catalyst and sodium sulfate as gelatinization inhibiter.

目的 以木薯淀粉为原料，醋酸酐为乙酰化试剂，NaOH为催化剂，Na2SO4为膨胀抑制剂，制备了低取代度木薯淀粉醋酸酯。

A selective and mild PS-DIB/ionic-liquid immobilized 2, 2, 6, 6-tetramethyl-piperidin-4-ol-N-oxyl catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via the iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TeMPO catalyst, 4-(2, 2, 6, 6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from TeMPO and 1, 4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化，制得了负载型二乙酰氧碘苯作为氧化剂。2， 2， 6， 6-四甲基－N-氧自由基哌啶醇与1， 4-二溴丁烷反应生成4-溴丁氧基－2， 2， 6， 6-四甲基－哌啶－1-氧化物，再与N-甲基咪唑发生季铵化反应，生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2， 2， 6， 6-四甲基－N-氧自由基哌啶负载离子液体。

A selective and mild PS-DIB/ionic-liquid immobilized TEMPO catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via Iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TEMPO catalyst, 4-(2,2,6,6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from 2,2,6,6-tetramethyl-piperidin-4-ol-N-oxyl and 1,4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化，制得了负载型二乙酰氧碘苯(diacetoxyiodo polystyrene，PS-DIB)作为氧化剂。2，2，6，6-四甲基-N-氧自由基哌啶醇(2，2，6，6-tetramethyl-piperidin-4-ol-N-oxyl，TEMPO)与1，4-二溴丁烷反应生成4-溴丁氧基-2，2，6，6-四甲基-哌啶-1-氧化物，再与N-甲基咪唑发生季铵化反应，生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2，2，6，6-四甲基-N-氧自由基哌啶负载离子液体TEMPO-IL。

We found that NaBu stimulated ALAS2 gene expression not only in erythroid K562 cells, but also in non-erythroid 293T cells with a concurrent increase in acetylation level of histone H3 and dimethylation level of K4 at the same histone at ALAS2 gene promoter.

同时ALAS2基因启动子的组蛋白H3乙酰化水平以及组蛋白H3的第4位赖氨酸的双甲基化水平升高。

The synthesis of nalbuphine hydrochloride from thebaine as starting material was through following processes:oxidation,high-pressure hydrogenation,acetylation,removing methyl of 3-methoxy,hydrolysis,condensation,reduction and finial salification.

以蒂巴因为起始原料，经氧化、高压氢化、乙酰化、氰化、脱3-位甲氧基的甲基、水解、缩合、还原、成盐，合成了盐酸纳布啡，总收率达18。

Histone acetyltransferases and deacetylases function antagonistically to control histone acetylation.

组蛋白的乙酰化在调节染色体结构和功能中起着重要的作用，而这种调节受组蛋白乙酰化酶和去乙酰化酶的共同调节。

In addition,α-alkenoyl ketene--acetals mainly used as the synthons of 3C and 5C, theα-functionalized reactions of which just limited on some simple reactions, as bromination, nitration, acetylation. However, the understanding of the forming of C-C bond atα-position is far from enough.

另外，对于α-烯酰基二硫缩烯酮的研究则主要集中在其作为3C或5C合成子的研究上，其α-位的官能化研究只是停留在溴化、硝化、脱羧等简单的反应之上，而对α-位C-C键的形成还缺乏足够的认识。

The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉素为起始原料，经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。