查询词典 acetonitrile

The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

采用C8柱，以0.045mol/L磷酸二氢胺溶液∶乙腈(2∶1)(用三乙胺调pH至7.35)为流动相，流速1ml/min，检测波长210nm，柱温40℃。结果阿奇霉素的线范围为50.3～1006μg/ml，平均回收率100.1%，r=1.0000，RSD=0.8%(n=9)。

ABSTRACT Objective To establish an HPLC method for the determination of azithromycin powder.Method The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

阿奇霉素为氮杂内酯类抗生素，日抗基和《中国药典》2005年版［1］均采用微生物检定法测定其含量，《欧洲药典》4.6版和USP26版中均采用HPLC法，专属性较强，试验周期短，但均使用的是聚合物极性柱，《欧洲药典》柱温为70℃，USP采用电化学检测器，其采用的设备在我国药检部门尚未普及［2］。

Anhui Institute for Drug Control, Hefei 230051ABSTRACT Objective To establish an HPLC method for the determination of azithromycin powder.Method The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

阿奇霉素为氮杂内酯类抗生素，日抗基和《中国药典》2005年版［1］均采用微生物检定法测定其含量，《欧洲药典》4.6版和USP26版中均采用HPLC法，专属性较强，试验周期短，但均使用的是聚合物极性柱，《欧洲药典》柱温为70℃，USP采用电化学检测器，其采用的设备在我国药检部门尚未普及［2］。

Methods The HPLC System consisted of Agilent Plus C18 column, acetonitrile-buffer(0.01mol · L-1 monobasic potassium phosphate, contained 0.1% triethyl amine, pH 6.8 )(70∶30) as mobile phase with detection wavelength 282nm.

采用 Agilent Plus C18柱；以0.01mol · L-1磷酸二氢钾溶液（含0.1%三乙胺，用磷酸调节 pH 值至6.8）-乙腈（30∶70）为流动相；检测波长：282nm 。

Bis-imidazoline was prepared from triethylene tetraamine and N,N-dimethylformamide dimethyl acetal at 85℃ for 2 h with toluene as solvent, with a yield of 90.4%. The reaction of bis-imidazoline with 1,2-dibromoethane and potassium carbonate in acetonitrile provided with a monobromide salt yield of 78.7%. Hydrolysis of monobromide salt under aqueous causic solution formed 1,4,7,10-tetraazzcyclododecane in a 74.2% yield.

用甲苯作溶剂，使三乙烯四胺和N，N-二甲基甲酰胺二甲基缩醛在85℃反应2 h，得到中间体双咪唑啉，产率90.4%，在乙腈溶剂中，碳酸钾存在下，双咪唑啉和1，2-二溴乙烷进行扩环反应，得到环状中间体一溴盐，产率78.7%，一溴盐经碱性水解2 h，得到1，4，7，10-四氮杂十二烷，产率74.2%。

There are great differences between the nonaqueous acetonitrile system and aqueous one on the frequency of the vibration of ν O-H, whose value is higher in nonaqueous system.

处于非水环境下的水分子的VO-H与水系相比存在明显的差别。水分子间的氢键被不同程度地破坏导致几种模式下的水分子VOH均要高于水体系。

A GC headspace injection method for the determination of residual organic solvents such as methanol, ethanol, acetonitrile, dichloromethane, ethylacetate, 4 methyl 2 pentanone, toluene, DMF, chloroform and tetrahydrofuran in tazobactam was established.

建立了气相色谱顶空进样法测定三唑巴坦中甲醇、乙醇、乙腈、二氯甲烷、乙酸乙酯、甲基异丁基酮、甲苯、N ，N′-二甲基甲酰胺、氯仿和四氢呋喃等有机溶剂的残留量。

Mm, 5 μm and a UV detector. Elution was performed at a flow rate of 1 mL/min, with a gradient of methanol-acetonitrile-water starting at 80∶10∶10, increasing linearly to 86∶10∶4 in 35 min, then returning to the initial conditions in 5 min. Elution of phenacyl esters was monitored by absorbance at 254 nm. Pentadecanoic acid was used to be an internal standard.

分析所用色谱柱为ZORBAXSB C18柱，以十七酸作为内标，甲醇-乙腈-水为流动相，采用梯度洗脱(梯度洗脱程序为甲醇-乙腈-水由80∶10∶10在35 min内线性变化到86∶10∶4，然后在5 min内恢复到起始比例，流动相流速为1 mL/min)，通过测定苯乙酰甲酯在254 nm处的吸光度值来测定脂肪酸含量。

Different chromatographic parameters including elution profiles, column temperature were investigated in order to optimize separation conditions of different fatty acid phenacyl ester derivatives. A gradient elution using methanol/acetonitrile (90:10, V/V)-water as mobile phase at 0.35 mL/min, detection wavelength at 246 nm, and column temperature of 35℃ were chosen.

经优化确定以(90：10)-水为流动相梯度洗脱，在检测波长246 nm，柱温35℃，流速0.35 mL/min的色谱条件下，18 min内能完成对13种脂肪酸衍生物的分离检测。

Tetra-O-benzyl-D-glucose reacted with bromine to give glucosylbromide. It reacted with hydroxyl phenyl acetonitrile or hydroxyl benzaldehyde to give substituted ph- enylacetonitrile or substituted benzaldehyde.11 New stilbenes were synthesized possessing 2,3,4,6-tetra-O-benzyl-D-glucoside by condensation reaction with pheny lacetonitrile or benzaldehyde, which had potential biological activity and would be sieved in the future.

由2，3，4，6-四芐氧基葡萄糖作为中间体，首先制备出的溴代糖和含有羟基的苯甲醛和苯乙反应制备出含有糖的取代苯甲醛和取代苯乙，再和简单的苯乙或苯甲醛缩合反应生成11种具有潜在的生物活性且含有2，3，4，6-四芐氧基葡萄糖的类化合物，这些新化合物有待于进一步进行药理活性筛选。

Now, however, all children continue in "comprehensive" schools, and the eleven-plus determines which courses of study the child will follow.

然而现在，所有的孩子都要在综合学校继续学习，所以这次考试只是决定他们将要学习哪些课程。

Cultivatable land , and led to a general recognition that development must not be carried at the cost of agriculture .

城区的迅速扩大在很多情况下侵占了宝贵的可耕地，使人们普遍认识到发展不能以牺牲农业为代价。