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Methods Establishing S180 tumor model, and establishing the model of pyretic syndrome by alcohol. all of the groups were divided into five groups: tumor group, Rexie group, Xiaotansanjie group, Qingrexiaotan group, chemotherapy group. At the first week, the Rexie group was lavage 50% alcohol (CO:0.65ml/ml)0.2ml/20g, once a day . The second day after the model established, the mice start to be administered.

方法建立热邪干预下的S180肿瘤模型，动物随机分为五组：单纯肿瘤组、热邪干预组、消痰散结组、清热消痰散结组、化疗组；其中热邪干预组、消痰散结组、清热消痰散结组、化疗组于种植S180肉瘤细胞前一周每天灌胃50%乙醇(浓度0.65ml/ml)0.2ml。

Rats in control group and model group received 0.9% sodium chloride solution 10 mL/kg. Rats in compound danshen dripping pills group received 0.75% compound danshen dripping pills 10 mL/kg. Rats in Xintongzhi drop pill high dose group and Xintongzhi drop pill low dose group received 3.6%, 1.8% Xintongzhi drop pill 10 mL/kg, respectively. After 7 days except control group, myocardial ischemia models were established by ranine vein of hypophysin in other four groups. The changes of lactate dehydrogenase,α-Hydroxybutyrate Dehydrogenase, creatine kinase, creatine kinase MB and ECG were recorded in each groups.

正常组和模型组予0.9%氯化钠注射液，复方丹参滴丸对照组予0.75%复方丹参滴丸水溶液，心痛治滴丸高剂量组、心痛治滴丸低剂量组分别给予3.6%、1.8%的心痛治滴丸水溶液，各组均10 mL/kg，每日1次灌胃。7日后除正常组外，其余4组均采用垂体后叶素0.5 U/kg舌下静脉注射制备大鼠急性心肌缺血模型，并检测各组乳酸脱氢酶、α-羟丁酸酶、磷酸肌酸激酶及磷酸肌酸激酶同工酶和心电图的改变。

Results: There was no difference of age, BMI, AHI and pulse oxygen between the stricture group and the nonstricture group. The coronal and the arrow diameters of the stricture group were less than those of the nonstricture group. The thickness of the retropharyngeal and lateral pharyngeal wall, and the width and length of the tongue of the stricture group were larger than those of the nonstricture group.

结果：两组患者的一般临床资料无明显差别，舌后区狭窄组的舌后区呼吸道左右径、前后径明显小于非狭窄组，狭窄组的咽后壁、咽侧壁软组织厚度、舌体宽度、舌体长度和舌体截面积等CT测量数据明显大于非狭窄组。

Results: There was no difference of age, BMI, AHI and pulse oxygen between the stricture group and the non-stricture group. The coronal and the arrow diameters of the stricture group were less than those of the non-stricture group. The thickness of the retropharyngeal and lateral pharyngeal wall, and the width and length of the tongue of the stricture group were larger than those of the non-stricture group.

结果：两组患者的一般临床资料无明显差别，舌后区狭窄组的舌后区呼吸道左右径、前后径明显小于非狭窄组，狭窄组的咽后壁、咽侧壁软组织厚度、舌体宽度、舌体长度和舌体截面积等CT测量数据明显大于非狭窄组。

The preferred organometallic compounds of the present invention are of the formula (R1)m M(PR23)x, where M is a metal selected from the group consisting of manganese, technetium, rhenium, iron, cobalt, nickel, ruthenium, rhodium, palladium, osmium iridium and platinum wherein m is 0, 1, 2, 3 or 4; x is 2, 3, 4 or 5 and m+x are 2, 3, 4, 5, 6, 7 or 8, m and x selected according to each metals appropriate valence; each R1 is independently selected from the group consisting of hydrogen, deuterium, N2, H2, D2 and a variety of substituted alkyl groups; each R2 is independently selected from the group consisting of lower alkyl, aryl, arylalkyl, and alkyl-Z, aryl-Z and arylalkyl-Z where Z is selected from the group consisting of oxy, silyl, siloxy, oxysilyl, siloxy, oxysiloxy, silyalkyl, oxysilylalkyl, siloxyalkyl, oxysiloxyalkyl, silylalkoxy, silylalkoxy, siloxyalkoxy and oxysiloxyalkoxy; and wherein when M is cobalt and one group R1 is selected to be N2, then m is 2 and the second group R1 is hydrogen or deuterium.

有机化合物的首选本发明的配方是米(R1代)米×(pr23)、那里是一米的金属挑选出来，第一组由锰、锝、铼、铁、钴、镍、钌、铑、钯、锇、铱铂其中M是0、1、2、3或4； X是2，3， 4或5米×+有2，3，4，5，6，7或8 米和X挑选合适的价按每个金属； R1的是每一组由独立选自氢、氘、氮、氢气、 D2和各种烷基取代群体； R2中的每个组由独立选自烷基低、芳、芳基烷基、烷基的Z、芳基、芳基烷基的Z-那里的ZZ是选自组风、含硅、氧、oxysilyl、硅、oxysiloxy，silyalkyl， oxysilylalkyl，siloxyalkyl，oxysiloxyalkyl，silylalkoxy，silylalkoxy，siloxyalkoxy和oxysiloxyalkoxy；其中，M是当钴一派R1的选择是氮气、然后是2米，第二组R1的氘是氢或者。

Methods(1) The behavioral frequency of male on chase,fighting,mounting of norway rat which divited into five groups,every group had 6 individuals that containing sterilely high grade(2,group 1),major low grade(5,group 2),fewer low grade(2,group 3),mixing with normal individuals 4,1,4 making 3 groups together with 6 sterile individuals(group 4) and 6 normal males(control,group 5) then constituting in 5 groups were obser...

方法(1)春季将30只雄性褐家鼠分为5组，每组6只；其中不育高等位鼠2只、多数低等位鼠5只、少数低等位鼠2只，混以普通可育鼠4、1、4只作为1~3组，不育鼠6只和正常可育鼠6只为第4组和对照组，观察其追逐、斗殴、爬跨行为。

Methods40 adult male SD rats were used in this study and divided into 4 groups at random: normal group, aging model group, TNY treatment group, and negative control group, each group had 10 rats. The subacutely aging rats were made by injecting Dgal into the rats' abdominal cavity continuosly. The learning and memory ability of rats in each group were detected with Morris water maze. The monoamine transmitter contents in hypothalamus and hippocampus were detected with HPLCECD.

方法选用成年雄性SD大鼠40只，随机分为4组，每组10只：正常组、衰老模型组、TNY用药组、阴性对照组。D半乳糖连续腹腔注射制作亚急性衰老的大鼠模型，采用Morris水迷宫检测各组大鼠的空间学习记忆能力及采用高效液相色谱电化学法检测各组大鼠下丘脑、海马NE，DA，5HT的含量。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P＞0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P＜0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P＜0.05).The levels of CGRP and SP in CSD group were higher than control group(P＜0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P＞0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P＜0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P＜0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P＜0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P＜0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P＜0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P＜0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD；同侧TNC放电频率，CSD中＞CSD后＞CSD前P＜0.05对侧TNC放电频率，CSD前、中、后无统计学差异(P＞0.05氟桂利嗪组同侧TNC放电频率，CSD前＞CSD中(P＜0.05)，CSD前与CSD后及CSD中与CSD后之间无统计学差异(P＞0.05)。2.1关于放免测定，各组血浆CGRP、SP水平有统计学差异(P＜0.05)，CSD组高于对照组(P＜0.05)，CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P＞0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P＞0.05.2关于免疫组化研究，右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P＜0.05)，多重两两比较结果CSD组大于对照组(P＜0.05)，CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P＞0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P＞0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P＜0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P＜0.05，蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P＜0.05，false discovery rate，FDR校正疼痛状态与非疼痛状态比较，同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P＜0.05，蒙特卡罗模拟校正。

The serum levels of TChE and SOD and CAT in hippocampus of mice in Cold group was also significantly higher than those in the Control group and Warm group(P 0.05或P 0.01),while the serum level of MDA in the Control group and Warm group were higher than that in the Cold group(P 0.05或P 0.01). Conclusion:(1)Long proper winter swimming could improve learning and memory abilities of mice.(2) Winter swimming could improve the ability of learning and memory by coordinate the content of acetylcholinesterase (3) This effect may be related to the decreased activity of TChE and the increased activity of anti-oxidatio.

1长期适量的冬泳运动可以促进小鼠学习记忆能力。2冬泳运动可以通过增加小鼠脑内海马组织中ACh的含量而影响TChE的活力。3冬泳运动促进学习记忆的机制可能是：3.1冬泳运动通过冷应激引起的神经内分泌系统的反应，来改变中枢神经系统的功能，使小鼠脑内乙酰胆碱的代谢增强、含量增加，从而促进学习记忆能力。3.2冬泳运动通过增强机体清除自由基的能力，来减轻脂质过氧化的程度，对小鼠的脑损伤起到保护作用，从而促进学习记忆能力。

Results Patients who had at least one abnormal result of liver function test accounted for 70.99% in untreated group and 61.07% in treated group. The most common abnormal hepatic function parameter in patients with thyrotoxic hepatic lesion was increased alkaline phosphate enzyme, which was 57.3% in untreated group and 51.0% in treated group. Abnormalities of alanine transaminase, aspartate transaminase, gamma-glutamyl tyanspeptidase and total bilirubin were 28.2%(37/131), 18.3%(24/131), 10.7%(14/131) and 21.4%(28/131) in untreated group and 21.5%(32/149), 15.4%(23/148), 4.7%(7/149) and 20.1%(30/149) in treated group, respectively. The possibility of thyrotoxic hepatic dysfunction was correlated with the patients' age and FT3 and FT4 levels, but not with the genesis and course of disease, sex, family history of hyperthyroidism, or levels of TGAb and TMAb. Conclusion Abnormal results of liver function test are commom in patients with hyperthyroidism.

结果 在未治组甲亢性肝功能损害的发生率为70.99%，经治组为61.07%；甲亢性肝功能损害最常见的异常指标是碱性磷酸酶增高，未治组、经治组分别为57.3%、51.0%；血清谷丙转氨酶异常在两组的发生率分别为28.2%、21.5%；血清谷草转氨酶异常在两组的发生率分别为18.3%、15.4%；总胆红素异常在两组的发生率分别为21.4%、20.1%；谷酰胺转肽酶异常的发生率未治组和经治组分别为10.7%、4.7%；甲亢性肝功能损害的发生与病程、甲状腺疾病家族史、性别、TGAb水平、TMAb水平无关，与年龄、甲状腺激素水平有关。

Nowadays, most of research are to build a transmutative Petri Nets through adding controlling place sets, controlling arc sets and controlling policy to the basic Petri Nets, while the Controlled Petri Nets could be used to argue many controlling theory problems conveniently and to induce many logically and physically supervisory and solve the Event Feedback Controlling Problems and State Feedback Controlling Problem in DEDS supervisory theory.

目前大多数的研究表现为在变形后的受控Petri网基础上，利用各种方法求得各种逻辑型、结构型控制器，解决DEDS监控理论中的事件反馈控制问题与状态反馈控制问题。

On one hand, there are discussions with the works council and union about extension of short time working up to the end of September.

一方面，有讨论，工程理事会和联盟关于延长工作时间短至9月底。