查询词典 Valeriana

Our research fixed that Iridoids composition of Valeriana jatamansi Jones was the active ingredient in Valeriana jatamansi Jones treating IBS for the first time.

综上所述，蜘蛛香环烯醚萜可以抑制胃肠功能亢进，降低内脏敏感性，改善精神状态，并具有良好的镇痛作用，从而改善腹泻型IBS的临床症状。

Sugar water choosed degree have no significant change. It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进，降低慢性应激所致IBS模型大鼠的内脏敏感性，显著减少了IBS模型大鼠的排便数量，从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的：探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of normal mice.1.2 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of mice with reserpineMethods:Compared with normal group,model group and YJBH group,mice with reserpine which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 6 days drug given.

结果：蜘蛛香环烯醚萜35.6mg/kg、17.8mg/kg组能减缓胃排空和小肠推作用(P.05)，说明蜘蛛香环烯醚萜对正常小鼠胃肠功能有一定的抑制作用。1.2蜘蛛香环烯醚萜对利血平化小鼠胃肠功能的作用方法：小鼠每日腹腔注射利血平造模，同时灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组、模型组和越鞠保和丸组对照，给药6日后测定动物的胃排空率和小肠推进率。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进，降低慢性应激所致IBS模型大鼠的内脏敏感性，显著减少了IBS模型大鼠的排便数量，从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的：探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

Based on this,We designed a series of experiments to study the treatment and its mechanism of Iridoids composition of Valeriana jatamansi Jones of the IBS animal model.1 Research on Iridoids composition of Valeriana jatamansi Jones in the role of gastrointestinal function.1.1 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of normal miceMethods:Compared with normal group and YJBH group,mice which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 4 days drug given.Results:Compared with normal group,gastric emptying and small intestinal propulsion in 35.6mg/kg and 17.8mg/kg group was inhibited.

课题通过观察蜘蛛香环烯醚萜对正常及IBS模型动物的胃肠道功能、精神活动的影响，以及蜘蛛香环烯醚萜干预下IBS大鼠结肠、血清、中枢5-HT含量，结肠5-HTR3A受体的mRNA和色氨酸羟化酶(TPH1)的mRNA表达，结肠和血浆中SP和VIP含量以及结肠中肥大细胞分布，探讨蜘蛛香环烯醚萜对腹泻型IBS的治疗作用及其作用机理，为临床治疗IBS提供实验依据。1蜘蛛香环烯醚萜对胃肠功能的作用目的：探讨蜘蛛香环烯醚萜对胃肠功能的影响1.1蜘蛛香环烯醚萜对正常小鼠胃肠功能的作用方法：正常小鼠灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组和越鞠保和丸组对照，给药4日后测定动物的胃排空率和小肠推进率。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时，蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数，说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环烯醚萜对外周和中枢5-HT含量的影响目的：探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环(来源：49ABC论文网www.abclunwen.com)烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时，蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数，说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环(来源：5bABd5C论文网www.abclunwen.com)烯醚萜对外周和中枢5-HT含量的影响目的：探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

It may means that Iridoids composition of Valeriana jatamansi Jones doesn\'t regulate the TPH1 transcription expression.3.4 Effection of Iridoids composition of Valeriana jatamansi Jones on SP and VIP of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

造模后，中枢5-HT呈现降低趋势，这可能是导致动物出现活动能力下降和兴趣缺失的原因之一，蜘蛛香环烯醚萜可以增加下丘脑、海马和杏仁核中5-HT含量，推断蜘蛛香环烯醚萜可通过干预中枢的5-HT通路来改善IBS精神症状。3.2蜘蛛香环烯醚萜对胃肠激素的影响目的：探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠SP和VIP的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

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