查询词典 Trail

We further evaluated the synergistic cytotoxicity of TRAIL in combination with actinomycin D, cisplatin and paclitaxel in A549 cell lines in vitro and in vivo.

本实验选择了人肺腺癌A549细胞瘤株作为我们实验研究的对象，通过TRAIL对人肺腺癌A549细胞诱导凋亡研究，在A549的荷瘤裸鼠的动物模型上研究了其体内的抗肿瘤活性，并进一步研究了TRAIL与化疗药物放线菌素D(actinomycin D，Act D)、紫杉醇和顺铂(cisplatin，CDDP)的联合作用对人肺腺癌A549细胞的体外协同抗肿瘤活性，通过化疗药物协同增强TRAIL抗肿瘤活性作用机制的初步研究，为降低临床化疗药的用药量，减轻其对机体的不良反应提供一定的理论基础。

This caused significant problems for the breadcrumb trail design, as there could theoretically be two or more breadcrumb trails for content.

但是这给"breadcrumb trail"导航的设计带来了大麻烦，因为理论上一条内容可能包含两个或三个"breadcrumb trail"。

While riding on a horse trail doesn't guarantee that you won't come across an inconsiderate person who has ignored the signs and is tearing down the trail on his bike, it certainly lowers the likelihood of this happening.

而骑在一匹马古道并不保证你不会碰到一个不人谁忽视了的迹象，并拆除了TRAIL对他的自行车，当然降低的可能性，这种情况出现。

Strongly positive immunostained thyroid follicular cells of EAT rats for TRAIL mainly distributed adjacently to infiltrating lymphocytes. Staining of infiltrating lymphocytes for TRAIL was found to be rather weak or even absent.

桥本甲状腺炎大鼠中TRAIL免疫染色强阳性甲状腺滤泡细胞多分布于浸润淋巴滤泡附近，浸润淋巴细胞中TRAIL免疫染色较弱。

Treatment with demethylation agent 5-Aza-CdR can lead to expression of silenced caspase 8 gene and restoration of sensitivity of gastric cancer cells to TRAIL.

胃癌细胞对TRAIL耐药与caspase-8的表达下调有关，5-Aza-CdR能增强caspase-8的表达，恢复胃癌细胞对TRAIL的敏感性。

Finally, we used GF109203X, Rottlerin, PKC-delta antisense RNA and PKC-epsilon siRNA to inhibit PKC activation or expression, and then observed their effects on TRAIL-induced apoptosis.

当以Rottlerin处理细胞时，均会增加细胞对於TRAIL的感受性。除了H1299细胞，p53能透过藉由Rottlerin抑制PKC-delta的活性，进而增加细胞对TRAIL诱导细胞凋亡的情形。

Basic on the special mechanism of action of Apo2L/TRAIL, the broad-spectrum antitumor activity and superordinary safety of recombinant human soluble Apo2L/TRAIL in preclinical researches, and the progression of the antitumor study on endogenous antiangiogenic factors, two studies were involved in this paper, including phase I clinical trial of rh-Apo2L and the study on expression of the fusion proteins of human Apo2L and endogenous antiangiogenic factors.

基于Apo2L／TRAIL独特的作用机制、重组人可溶性Apo2L／TRAIL临床前体现出的广谱的抗肿瘤作用和良好的安全性、以及内源性血管生成抑制因子抗肿瘤研究进展，本课题开展了下述两方面的研究：①国产重组人凋亡素2配体(rh-Apo2L)的Ⅰ期临床研究；②人Apo2L／TRAIL与人血管生成抑制因子融合表达的基础研究。

Previous results of the sensitivity of NSCLC to TRAIL—indued apoptosis show that H460 and A549 are the most sensitive to TRAIL;H1299 and H1355 are the most resistance to TRAIL.

在本实验室先前的研究中显示，从十株人类非小型肺癌细胞株中筛选对TRAIL敏感及具抗性之细胞株，结果发现H460对 TRAIL 最敏感，其次为A549；而 H1299 、H1355则对 TRAIL 最具有抗性。

Transfect YTMLC cells with Ad-TRAIL and determine the expression of TRAIL by IFA and flow cytometry.

以Ad-TRAIL转染YTMLC细胞，采用免疫荧光法和流式细胞术检测TRAIL基因的表达。

Results: Normal mature IEC expressed low TRAIL levels, whereas, in inflammatory lesions, TRAIL messenger RNA and protein were markedly up-regulated in IEC and lamina propria lymphocytes at levels comparable with trinitrobenzene sulfonic acid-induced colitis.

结果：正常成熟IEC表达低水平的 TRAIL ，而炎性病灶IEC及薄固有层淋巴细胞中的TRAIL信使RNA和蛋白显著上调，其水平可与由三硝基苯磺酸诱导的结肠炎相近。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。