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By means of cephalometric analysis and computeraid operative simulation, the best surgical proposal were gained. Results 15 cases were treated by TMJ reconstruction、 Jaw advancement by transplanted with bone graft and ramus sagital osteotomy, and genioplasty, 3 of the cases treated secondarily by Le fort I osteotomy.

采用电脑辅助的诊断和手术模拟及预测系统,获得充分扩展口咽和纠正颌面畸形的最佳手术方案,以TMJ重建、牵引成骨和正颌外科方法治疗患者。

METHODS: From April 1998 to February 2002, 12 patients with micromandibular deformity associated with OSAS (aged 14-36 years, 7 females and 5 males) were treated. Invert "L" shape ramus osteotomy and inverted replantation of posterior segment of ramus were performed to reconstruct the TMJ with the jaw advancement and genioplasty at the same time in 7 cases; mandibular angle osteotomy, bone grafts and genioplasty in 3 cases; and the jaw advancement by ramus sagittal osteotomy and genioplasty in 2 cases of the first branchial arch syndrome. RESULTS: The follow-up period was 6 months to 4 years.

1998年4月~2002年2月,对12例(女7例,男5例,年龄14~36岁)伴有严重OSAS症状及张口度0~3.0 cm的小下颌畸形患者,7例采取下颌升支倒&L&形截骨、升支倒置颞下颌关节重建术的同时施行下颌体部前徙和颏成形术;3例在颞下颌关节重建术后进行下颌角部截骨、植骨下颌骨前徙术;2例施行下颌升支矢状劈开、下颌骨前徙术。

Cases underwent bilateral TMJ reconstruction, bone graft and genioplasty in order to advance the jaw. Bimaxillary surgical procedure was completed in 3 cases, and distraction osteogensis and TMJ reconstruction in 6 cases. Al patients gained good appearance, 29 patients can open their mouth larger than 3 cm, and one case had recurrent TMJ ankylosis. 29 cases'AI<5 and oxygen saturation degree >90%(included the patient that had recurrent TMJ ankylosis).

结果 本研究有15例患者接受患侧下颌升支倒置TMJ重建、植骨前移,健侧升支矢状劈开、下颌前移和颏前移成形术;其中有3例行二期的上颌的Le Fort Ⅰ截骨术。6例行双侧TMJ重建、植骨前移下颌和颏成形术。3例施行同期双颌截骨前移和颏成形术;6例行单或双侧TMJ重建、牵引成骨术。

Objective to study the changes of endothelin and nitric oxide in gingival tissue of periodontitic patients and their relationship with local bone absorption.

目的 为了探讨慢性牙周炎患者牙龈组织中ET和NO的改变与局部颌骨的吸收及骨质疏松的关系。

A: glutin orientative bone, but a higher purity, matozoa, is a high purity of the prion protein.

答:明胶成分近似骨胶,但纯度较高,胶体透明,是一种纯度高的朊蛋白质。

Making glutin chermcal as quality fresh animal skin, bone and reseaarch rrepublic of glutin before they are used to join the water around the 50?

制作明胶的原料为优质新鲜的动物皮。

Results The results indicated that the cultured human alveolar bone origin cells from 3 patients could successfully express the osteoblasts phenotype in single layered culturing after stimulated by β-glycerophosphate and Dexamethasone.

结果自3人下颌齿槽骨分离培养的齿槽骨细胞在加入β-磷酸甘油和地塞米松刺激的体外培养条件下,均可成功表达成骨细胞的表现型,与同源成纤维细胞相比,差异有显著性(P.05)。

The passage 3 rat bone marrow mesenchymal stem cells were cultured at the density of 5×107/L in different groups, the induced group was added into conditioned medium containing 1×10-8 mol/L dexamethasone, 10 mmol/L beta-sodium glycerophosphate and 50 mg/L ascorbic acid at the same time of seeding, at 50%-60% confluence, at 85%-90% confluence, respectively.

将第3代大鼠骨髓间充质干细胞以5×107 L-1密度分组培养,诱导组分别于接种当时、细胞达50%~60%融合时、细胞达85%~95%融合时加入含地塞米松、β-甘油磷酸钠、维生素C的成骨诱导培养基诱导。

BMSCs were isolated from adult rats by modified bone marrow culture method. BMSCs were inoculated in basic medium containing 10%fetal bovine serum, high glucose DMEM, 100 U/L penicillin, 100 U/L streptomycin and 2 mmol/L glutamine in the control group. BMSCs were inoculated in conditioned medium (basic medium, 10 mmol/L β-glycerophosphoric sodium, 10-7 mol/L dexamethasone, 50 mg/L vitamin C).

通过改良的骨髓培养法分离成年大鼠骨髓间充质干细胞,对照组以基础培养液(10%胎牛血清+高糖DMEM+100U/L青霉素+100 U/L链霉素+2 mmol/L谷氨酰胺)培养,实验组用条件培养液(基础培养液,10 mmol/Lβ-甘油磷酸纳,10-7 mol/L地塞米松,50 mg/L维生素C)进行诱导培养。

The neck of femur were cut and stined with Masson Golder Trichrome for bone histomorphomemetric contrast group analysis.

在给药后3、4.5、6个月每组各取10只大鼠进行检测,先测量体重,空气栓塞处死,分离股骨颈,获得股骨颈样本,经切片等处理后,显微镜下作骨形态计量学检测。

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