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T-bone相关的网络例句

查询词典 T-bone

与 T-bone 相关的网络例句 [注:此内容来源于网络,仅供参考]

There was me and my monkey And with his dungarees and roller blades Smoking filter tips Reclining in the passenger seat of my super charged jet black Chevrolet He had the soft top down He liked the wind in his face He said son you ever been to Vegas I said no He said that's where we're gonna go You need a change of pace And when we hit the strip with all the wedding chapels and the neon signs He said left my wallet in El Segondo and proceeded to take two grand of mine We make tracks to the Mandalay Bay Hotel Asked the bell boy if he take me and my monkey as well He looked in the passenger seat of my car And with a smile he said If your monkey's got that kind of money sir Then we've got a monkey bed Me and my monkey With a dream and a gun I'm hoping my monkey don't point that gun at anyone Me and my monkey Like butch and the sundance kid Trying to understand why he did what he did Why he did what he did We got the elevator, I hit the 33rd floor We had a room up top with the paronama views like nothing you'd ever seen before He went to sleep in the bidest And when he awoke He ran his little monkey fingers through yellow pages Called up some escort services and ordered some okey doke Forty minutes later there came a knock at the door In walked this big bad ass baboom into my bedroom with three monkey whores Hi, my name is Sunshine, these are my girls Lace my palm with silver baby and oh yeah They'll rock your world So I watched pay per view and polished my shoes and my gun Was diggin' on Kurt Cobain singing about lithium There came a knock at the door and in walked Sunshine What's up you'd better get your ass in here boy Your monkey's having too much of a good time Got tickets to see Sheena Easton The monkey was high Said it was a burning ambition to see her before he died We left before encores he couldn't sit still Sheena was a blast baby but my monkey was ill We went to play blackjack kept hitting twenty three Couldn't help but notice this Mexican just staring at me Or was it my monkey I couldn't be sure It's not like you'd never seen a monkey in rollerblades and dungarees before Now don't test my patience cause we're not about to run That's a bad ass monkey boy and he's packing a gun My name is Rodrigue he says with death in his eye I've been chasing you for long time amigos And now your monkey's gonna die Me and my monkey Drove in search of the sun Now me and my monkey We don't wanna kill no Mexican But we've got Ten itchy fingers one thing to declare When the monkey is high You do not stare you do not stare You do not stare Looks like we've got ourselves a Mexican stand off here boy And I ain't about to run Put your gun down boy How'd I get mixed up with this fuckin' monkey anyhow

有我和我的猴子并且与他的dungarees 和路辗刀片抽烟过滤器要诀斜倚在我的超级被充电的喷气机黑色薛佛列汽车乘客座位他下来有软的上面他喜欢风在他的面孔他说您曾经是到维加斯I 说没有的儿子他说we're 去去的that's 您需要步幅的变动并且当我们击中了小条以所有婚礼教堂和霓虹灯广告他左说我的钱包在El Segondo 和进行采取二盛大我的我们做轨道对曼德勒海湾旅馆问响铃男孩如果他采取我并且我的猴子他看了在我的汽车乘客座位并且以微笑他说如果您的monkey's 得到了那金钱先生然后we've 得到了猴子床我和我的猴子与梦想和枪 I'm 希望我的猴子don't 把那杆枪指向任何人我和我的猴子象butch 和sundance 孩子设法了解为什么他做了什么他为什么他做了什么他我们得到了电梯,我击中了第33 楼我们有一间屋子上面以paronama 看法象没什么you'd 以前曾经被看见他去睡觉在bidest 并且当他醒了他跑了他小的猴子手指通过黄页召集了一些伴游服务和定购了一些okey doke 那里四十分钟以后来了敲在门在走了这大坏驴子baboom 入我的卧室与三个猴子妓女喂,我的名字是阳光,这些是我的女孩系带我的棕榈与银色婴孩和oh 呀 They'll 岩石您的世界如此我观看了薪水每看法和擦亮了我的鞋子和我的枪是diggin'在Kurt Cobain 唱歌关于锂那里来了敲在门和在走的阳光里 What's you'd 更好得到您的驴子在这里男孩您的monkey's 有太多好时光被得到的票看见Sheena Easton 猴子是高的前述这是灼烧的志向看见她在他死了之前我们离开在他couldn't 坐直的encores 之前 Sheena 是疾风婴孩但我的猴子是不适我们去演奏大酒杯继续击中二十三 Couldn't 帮助但注意这墨西哥人凝望我或是它I couldn't 是肯定的我的猴子 It's 不是喜欢you'd 以前从未被看见一只猴子在rollerblades 和dungarees 现在don't 测试我的耐心起因we're 不跑 That's 坏驴子猴子男孩和he's 包装枪我的名字是他说以死亡在他的眼睛的Rodrigue I've 追逐您为久时间朋友并且现在您的monkey's 去死我和我的猴子驾驶了寻找太阳现在我和我的猴子我们don't 不想要杀害墨西哥人但we've 得到了十个痒的手指一件事宣称当猴子是高的您不凝望您不凝望您不凝望看起来象we've 这里得到了墨西哥立场男孩并且I ain't 跑把您的枪男孩放下 How'd I 得到与这fuckin'混合;猴子无论如何或有我和我的猴与他dungarees和滚刀片吸烟过滤嘴斜倚在客运座位我国超级控喷射黑色雪佛兰他有软顶下来,他最喜欢的风在他的面对他的儿子说:你到过赌城我说没有,他说哪里,我们gonna你走需要改变步伐,而当我们打带所有的教堂婚礼和霓虹灯他说离开我的钱包在El segondo进而采取两项盛大的矿井,使我们路轨次电子曼德勒湾酒店询问钟男孩,如果他把我和我的猴子以及他的表情,在次电子乘客座位上我的车,面带微笑,他说,如果你的猴得到这笔钱思住宅,然后我们拿到猴床上,我和我的猴同一个梦想和一支枪,我希望我的莫 nkey不点炮人,在我和我的猴像布奇和森丹斯孩子设法了解后WH y他做他为何他做了什么,我们得到了电梯,我打到33楼,我们有一个房间顶与paronama看法没有像您见过会捶他睡在bidest而当他醒来,他跑他的小猴子手指透过黄坝天麻打电话询问过保姆服务,并订购了一些东西doke四十分钟左右,有一个前来敲门做或者走这个大坏驴子baboom到我的卧室有三名妓女猴喜,我的名字是阳光,硒是我的女孩花边我的手心与银宝宝,哦噢人家,你的摇滚世界,让我眼睁睁看着付每意见,并擦拭鞋子,我的枪是diggin '库尔特罗克塞特歌唱锂出现了一针玉在门口,并走在阳光下是怎么回事,你最好明白你的驴子在这里你男童和尚安永的有太大的一个好时机得到入场券见sheena伊斯顿猴高表示,这是燃烧的雄心,看到她生前我们离开之前,以encores他不能坐视sheena仍然是一个基本法 AST的婴儿,但我的猴子生病,我们去发挥酒杯一直打到23不禁通知书策墨这只是瞪着我,抑或是我的猴子,我也不能肯定它不像您在Neve 住宅看到一只猴子在晒太阳和dungarees之前,现在不考验我的耐心,我们的事业不是对办好次下午的一个坏驴子猴男孩和他的包装带枪我的名字是罗德里格说,他的死亡与他眼睛,我一直追你很久地球,现在你的猴死gonna我和我的博士猴脏器寻找太阳,现在我和我的猴子,我们不想杀任何墨西哥,但我们拿到碲氮手指发痒一回事申报时,猴子是高你不盯着你不盯哟美国不瞪眼样子,我们拿到了自己的立场,墨西哥产的男孩在这里,我并不是对办好把你的枪下男孩,我为什么会有这种攻防得到混为一谈这fuckin '猴不管怎样

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The rain is knockin at my heart and I can't see the sun no more I can't live without you my sun if I'm ever gonna get back picture this You got a kid in a room his hands sweatin and shakin while he's lacin his shoes the excitement's buildin up for what's comin up soon To get there and do what he was born to do He's listenin to the beats He's trying to get in the zone He's gotta take control and make every moment his own just a little bit tired he is a little bit scared but he's so focused he won't show it when he's finally there Cuz now he's out on the floor And he's catchin the pass slashin to the glass, movin so fast, right to the hole, they don't know how to stop him and he keeps on droppin 2's and 3's by the second and the crowd is rockin so they knock him knock him down to the ground before he's crowned as the best He takes a deep breath before he gets up and looks around Everything's in slow motion The crowd is an ocean Only one minute left The rain is knockin at my heart and I can't see the sun no more I can't live without you me sun if I'm ever gonna get back, get back, get back The rain is knockin at my heart and I can't see the sun no more Ican't lice without you my sunif I'm ever gonna get back Imagine A little girl in the stands the kid's her older brother and she's his number one fan He's always lookin out for her and she looks up to him and she wants nothin more than for her brother to win But the truth is that there's someone on the other team Someone who stole her heart Someone who holds her dreams They kiss for the 1st time just the other evening Her brother's 23 but her lover's number 16 The drama is set the whole scene is intense she doesn't know which one to cheer for and she's gettin upset 23 on the chase cuz they're at each other's necks and what happens next Her boyfriend steals the ball and checks the kid in the chest 16 on the break Brother goes in the air with brother up in his face They come crashing to the dirt Tears about to burst When the game is over who she gonna run to first, yo The rain is knockin at my door and I can't see the sun no more I'ma hafta fight my way if I'm ever gonna get back, get back, get back The rain is knockin at my door and I can't see the sun no more I'ma hafta fight my way if I'm ever gonna get back 有时感觉阻碍太多但我还是为了我的梦想而奋斗 Nothin's gonna stop me Ey yo this game of life is one big struggle We gotta hustle just to make it everyday to fight the fears we facin and grab those dreams we chasin cuz there ain't no competition when we rise to the occasion c'mon The rain is knockin at my door and I can't see the sun no more I'ma hafta fight my way if I'm ever gonna get back, get back, get back The rain is knockin at my door and I can't see the sun no more I'ma hafta fight my way if I'm ever gonna get back 注:IN可以看作是ING如FACIN可以看作facing

雨是敲入我的心我看不到太阳不再我不能没有你我的太阳如果我曾经去买回来此图片你有一个孩子在一个房间里他的手sweatin和沙金,而他的拉欣他的鞋兴奋的buildin了什么的,很快就要来要到那里做什么,他出生做他listenin的节拍他试图在该地区获得他得采取控制和利用自己的每一刻只是有点累了他有点害怕但他是如此专注,他将不显示它的时候,他终于有现在的Cuz他在地上他的捉通行证 slashin的玻璃,居无定得那么快,有权向孔,他们不知道如何阻止他他不断droppin 2的和3的由第二摇滚和人群所以他们会把他会把他撞倒在地之前,他的加冕为最佳他深吸了一口气,才起身环顾四周一切都在慢动作人群是一个海洋仅1分钟雨是敲入我的心我看不到太阳不再我不能没有你我的太阳如果我曾经去买回来,回来,回来雨是敲入我的心我看不到太阳不再没有你我的sunif Ican't虱子我曾经去买回来想像看台上的一个小女孩这个孩子是她的哥哥,她是他的头号球迷他总是在找谁了她和她抬起头来他和她想没什么比她的哥哥更赢得但是,事实是,对其他团队的人有人谁偷了她的心有人谁拥有她的梦想他们只是亲吻对方的第一时间为晚上她的弟弟,但她的爱人23的16号该剧设置整个场面激烈她不知道哪一个加油,她的gettin不高兴 23大通他们的Cuz在对方的脖子和接下来会发生什么她的男朋友抢断球,并检查孩子的胸部 16个突破哥哥和弟弟去他的脸在空中他们来到崩溃的污垢即将爆裂泪当比赛结束谁,她要去跑第一,溜溜雨是敲着我的门我看不到太阳不再我是打我的方式hafta 如果我曾经去买回来,回来,回来雨是敲着我的门我看不到太阳不再我是打我的方式hafta 如果我曾经去买回来有时感觉阻碍太多但我还是为了我的梦想而奋斗没办法,拢不惊安永哟这样的生活游戏是一个大斗争我们得喧嚣这只是为了日常战斗的恐惧,我们都会面临的两个并抓住那些梦想,我们查辛没有的Cuz没有竞争当我们挺身而出来吧雨是敲着我的门我看不到太阳不再我是打我的方式hafta 如果我曾经去买回来,回来,回来雨是敲着我的门我看不到太阳不再我是打我的方式hafta 如果我曾经去买回来

I can't stop my love for you 2つの爱が离れてしまわないように 1つに抱いててそれでも不安な夜は访れるものだからねそんなときはギュッと大げさに抱きしめていてかけがえのないもの君がたくさんここにくれただけど何よりもいちばんかけがえのないものは君なんだ I can't stop my love for you 2人语った未来に君との居场所があるように Oh baby I can't stop my love for you 君のすべてになってねつないだ手信じて歩いてゆくと誓うよ发音: I can't stop my love for you futari katatta mirai ni kimi to no ibasho ga aru you ni Oh baby I can't stop my love for you kimi no subete ni natte ne tsunaida te shinjite aruite yuku to chikau yo futari no me no mae nazomeki hirogatta mikansei na chizu demo totemo totemo kokoro ugoita… donna kotoba narabete mite mo katarikirenai omoi kono ai ga sasayaku yo itoshisa no imi o I can't stop my love for you futari ayumu supiido wa kitto onaji hazu ja nai kara ne moshi mo kimi no tonari kono te ga hanareta toki wa miushinawanai you ni kitto mukae ni kite ne "daikirai" nante uso demo iwanai kedo "daisuki" datte uso nanka ja iwanai kara ne aenai toki sae kimi wa nani mo kangaeru yoyuu mo nai kurai kono kokoro o hitorijime ni surun dakara I can't stop my love for you futatsu no ai ga hanarete shimawanai you ni hitotsu ni daitete sore demo fuan na yoru wa otozureru mono dakara ne sonna toki wa gyutto oogesa ni dakishimete ite kakegae no nai mono kimi ga takusan koko ni kureta dakedo nani yori mo ichiban kakegae no nai mono wa kimi nan da I can't stop my love for you futari katatta mirai ni kimi to no ibasho ga aru you ni Oh baby I can't stop my love for you kimi no subete ni natte ne tsunaida te shinjite aruite yuku to chikau yo

中文歌词: I can't stop my love for you 在我俩所诉说的未来里就像有着与你共处的栖身地一般 Oh baby I can't stop my love for you 请把我当成你的全部喔相系的手相信着我走下去发誓喔在我俩的眼前像谜般扩大的未完成地图可是非常非常心动……即使我尝试着用尽所有话语都无法诉说我的思念这个爱是悄悄的诉说喔爱的意义 I can't stop my love for you 因为我俩走路的速度应该一定不会是相同的才对啊如果当你的身边这相系的手离去时为了不失散你一定得要来接我喔虽然「最讨厌你了」这句话即使说谎也不说但是就是因为「最喜欢你了」这句话虽然不是说谎也不说啊连无法见面的时间你就像都无法思考任何其它东西般因为这个心你想独占 I can't stop my love for you 为了不让两个爱分离请将它抱在一起即使如此不安的夜晚也会来临的啊到时候请你要紧紧地夸张地抱住我喔无法替代的东西你在这里给予我很多话虽如此比任何东西都还重要无法替代的东西是你 I can't stop my love for you 在我俩所诉说的未来里就像有着与你共处的栖身地一般 Oh baby I can't stop my love for you 请把我当成你的全部喔相系的手相信着我走下去发誓喔日文歌词: I Can't Stop My Love For You 2人语った未来に君との居场所があるように Oh baby I can't stop my love for you 君のすべてになってねつないだ手信じて歩いてゆくと誓うよ 2人の目の前谜めきひろがった未完成な地図でもとてもとても心动いた…どんな言叶并べてみても语りきれない想いこの爱がささやくよ爱しさの意味を I can't stop my love for you 2人歩むスピードはきっと同じはずじゃないからねもしも君のとなりこの手が离れたときは见失わないようにきっとむかえに来てね大嫌い?

This ain't a love song 歌手:bon jovi this ain't a love song bon jovi i should have seen it coming when roses died should have seen the end of summer in your eyes i should have listened when you said good night you really meant good bye baby, ain't it funny, how you never ever learn to fall you're really on your knees, when you think you're standing tall but only fools are "know-it-alls" and i played that fool for you i cried and i cried there were nights that died for you baby i tried and i tried to deny that your love drove me crazy, baby if the love that i got for you is gone if the river i cried ain't that long then i'm wrong, yeah i'm wrong, this ain't a love song baby, i thought you and me would stand the test of time like we got away with the perfect crime but we were just a legend in my mind i guess that i was blind remember those nights dancing at the masquerade the clowns wore smiles that wouldn't fade you and i were the renegades, some things never change it made me so mad 'cause i wanted it bad for us baby now it's so sad that whatever we had, ain't worth saving if the love that i got for you is gone if the river i've cried ain't that long then i'm wrong, yes i'm wrong, this ain't a love song if the pain that i'm feeling so strong is the reason that i'm holding on then i'm wrong, yeah i'm wrong - this ain't a love song i cried and i cried there were nights that i died for you baby i tried and i tried to deny that your love drove me crazy baby if the love that i got for you is gone if the river i cried ain't that long then i'm wrong, yeah i'm wrong - this ain't no love song if the pain that i'm feeling so strong is the reason that i'm holding on then i'm wrong, yeah i'm wrong - this ain't a love song by lune the end JTL 很长时间Love Is A Pain (I don't cry)(I don't cry)(I don't cry)(I don't say) As time gose by

你身边的那个人看起来会比我做得更好放你离开的那个冬天,痛苦了好久,但是都没有用了开始我小心地走向你,你用阳光般的微笑接受了我的心那么想见你,落下了泪,但是(I don't cry)现在什么也无法说想说爱你,现在不再是我的你有的时候给我的问候的电话我说现在过得很好这样的话,但舌头无法像以前看到了我变瘦的样子,你也会吃惊放你离开的那个冬天,痛苦了好久,但是都没有用了开始我小心地走向你,你用阳光般的微笑接受了我的心那么想见你,落下了泪,但是(I don't cry)现在什么也无法说想说爱你,但现在不再是我的你如果对我说你回来吧我会再次抱着你如果只想看我一次,我会把空位子留给你说不定那个时候是我们两个再一次没有办法地擦肩而过的命运我这样疼痛,你也会非常疼痛的,那个时候你也说没有办法我的没有用的自尊心非常非常的后悔没有你,度过了很长时间,只一个人没有你,我忍受着,得生活下去,我没有自信那么想见你,落下了泪,但是(I don't cry)现在什么也无法说想说爱你,我想再见到你,但现在好象一切都结束了希望好久以来积攒的记忆,到什么时候都不会在时间里被埋没祝你幸福

T exist in solitary; some of T. t in oppositeness; the number of T. t in the form of chain is more than that of T. f; both T. f and T. t can be seen in thick growth. The size of T. t is a slightly bigger than that of T. f, the ends of T. f is somewhat blunt, while the ends of T.

此外还运用紫外诱变育种方法,将经适当紫外诱变处理的T.f正突变菌株用于浸矿,可提高细菌的亚铁氧化能力,使铜浸出率提高10%左右。

The research investigates the electromagnetic radiation intensity of MRI in some hospitals of southern Taiwan involving: Chung-Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung Verterans General Hospital, Chang-Gung Memorial Hospital Department of Kaohsiung, Chi Mei Medical Center Department of Tainan, Kaohsiung Municipal Hsiaokang Hospital, 802 Kaohsiung Armed Forces General hospital and Yuan's General Hospital etc. Finally, we got the result On the intensity of electromagnetic radiation was between 6.7μT to 7.8μT. Among these tests, the intensity of electromagnetic radiation of the head is ranged from 7.2μT to 7.6μT, the chest from 7.3μT to 7.7μT, the abdomen from 7.3μT to 7.8μT, the center of door from 6.9μT to 7.5μT, and the relater of control room from 6.7μT to 7.4μT.

本研究调查台湾南部几所医院-高雄医学大学附设中和纪念医院、高雄荣民总医院、长庚纪念医院高雄院区、奇美医院台南院区、高雄市立小港医院、802国军高雄总医院、阮综合医院等几所医院内,MRI作业场所电磁辐射强度,测量结果磁场强度范围介於6.7μT到7.8μT,其中头部磁场值范团7.2μT到7.6μT,胸部磁场值范围7.3μT到7.7μT,腹部磁场值范围7.3μT到7.8μT,门中央磁场值范围6.9μT到7.5μT,控制室中央磁场值范围6.7μT到7.4μT。

The storages of WSOC under 11 forest types were as follows: Pinus massoniana forest 2.43 ×10~6 t , robur mixed forest 1.57 ×10~6 t, shrubs 1.22×10~6 t, Cupressus funebris forest 0.46×10~6 t, Cunninghamia lanceolata forest 0.60×10~6 t, Citrus reticulate plantation 0.38×10~6 t, other soft broad leaved forest 0.22×10~6 t, the broad leaved and coniferous mixed forest 0.22×10~6 t, Neosinocalamus affinis 0.16×10~6 t, other hard broad leaved forest 0.20 ×10~6 t, temperate Pine forest 0.06×10~6 t.

本研究采用该方法测定的各主要森林类型下WSOC总贮量为6.53×10~6 t.11种森林植被WSOC库分别为:马尾松林2.43×10~6 t,栎类混交林1.57×10~6 t,灌木林1.22×10~6 t,柏木林0.46×10~6 t,杉木林0.60×10~6 t,柑桔林0.38×10~6 t,其它软阔林0.22×10~6 t,针阔混交林0.22×10~6 t,竹林0.16×10~6 t,其它硬阔林0.20×10~6 t,温性松林0.06×10~6t。

CD8~+ cell is the main T lymphocyte subset in spleen, and B lymphocyte mainly is IgG~+ cell, moreover the amount of these B lymphocytes could exceed CD3~+ T lymphocyte subset after 7 days. CD8~+ cell is the main T lymphocyte subset in tonsil of appendix, and B lymphocyte is IgM~+ cell, and the amount could exceed CD3~+ T lymphocytes after 35 days. After 21 days, B lymphocytes in esophago tonsil are the main IgA~+ cells and the amount exceeds CD3~+ lymphocytes. The amount of CD4~+ lymphocytes is more than CD8+ lymphocytes.4. CD3~+、CD4~+ and CD8~+ T lymphocytes in spleen mainly distribute in periarterial lymphoid sheath. However IgM~+、IgG~+ and IgA~+ cells mainly distribute in ellipsoid periarterial lymphoid sheath and germinal center. T lymphocytes in appendix tonsil mainly distribute in middle and inferior part of mucous and the B lymphocytes mainly in middle and mucous between 4~7 days. Whereafter T, B lymphocytes equably distribute in mucous. CD4~+ cells arrange tightly and mainly occupy the central part in aggregates of T lymphocytes in esophago tonsil and CD8~+ lymphocytes mainly distribute in periphery. Meanwhile B lymphocytes encircle the periphery of aggregates of T lymphocytes. The aggregates of B lymphocytes is mainly the germinal center with lots of IgM~+、IgG~+ and IgA~+ cells. Meanwihle T lymphocytes encircle the periphery of aggregates of B lymphocytes.5. There is an intimate relationship between the development of tissue structure of peripheral immune organs and lymphcytopoiesis. The maturation of tissue structure is stimulated by the immigration of lymphocytes and the mature tissue structure provides place where lymphocytes grow mature and functionate.

脾脏在21日龄时达到稳定,食管扁桃体和盲肠扁桃体均在35日龄时达到稳定;脾脏中T淋巴细胞亚群以CD8~+细胞为主,B淋巴细胞则以IgG~+细胞为主,并在7日龄后数量超过CD3~+T淋巴细胞;盲肠扁桃体中T淋巴细胞亚群以CD8~+细胞为主,B淋巴细胞以IgM~+细胞为主,并在35日龄后数量超过CD3~+T淋巴细胞;21日龄后,食管扁桃体中B淋巴细胞以IgA~+细胞为主,数量超过CD3~+细胞,CD4~+细胞的数量多于CD8~+细胞。4、在T、B淋巴细胞组织定位方面,脾脏中CD3~+、CD4~+和CD8~+T淋巴细胞主要分布在动脉周围淋巴鞘中,而IgM~+、IgG~+和IgA~+细胞主要分布在椭球周围淋巴鞘和生发中心中;4~7日龄时,盲肠扁桃体中T淋巴细胞主要分布在粘膜固有层的中下部区域,而B淋巴细胞则主要分布在中上部区域,随后各日龄T、B淋巴细胞均匀地分布在粘膜固有层中;在食管扁桃体的T淋巴细胞聚集物中,CD4~+细胞紧密排列,主要占据中央部位,CD8~+细胞主要散布在外周,同时B淋巴细胞又环绕在整个T淋巴细胞聚集物的外周;B淋巴细胞聚集物主要为生发中心,其中存在大量IgM~+、IgG~+和IgA~+细胞,同时T淋巴细胞又环绕在整个B淋巴细胞聚集物的外周。5、外周免疫器官的组织结构发育和淋巴细胞发生之间存在密切的关系,淋巴细胞迁入淋巴器官刺激组织结构的发育成熟,同时成熟的组织结构又为淋巴细胞发育成熟并行使功能活动提供场所。

Restrictive changes of TCR Vp repertoire and clonal expanded T cells could be found in peripheral blood T cells from patients with T-ALL. However, the clonal expanded T cells' property (clonal expansion leukemic cells or leukemia antigen-specific expansion T cells) should be further characterized. It may play a certain role on detection of minimal residual disease and design of anti-leukemia idiotypic vaccine. The dominant utilization of TCR VjJ repertoire could be found in peripheral blood T cells from patients with B-ALL, meanwhile clonal expansive T cells were existed. It may be a feature of the host immune response for leukemia-associated antigen. The clonal expansive tendency of T cells in V021 and VP23 subfamilies was rather obvious, which may be correlated with certain malignant B-cell clone. The CDR3 sequences of monoclonal expansive T cell in T cell strains were different, which was the base of developing DNA vaccine.

T-ALL患者外周血T细胞的TCR Vβ谱系出现限制性改变,均可检测到克隆性增殖T细胞,尚需进一步鉴定其性质(肿瘤性或抗原特异性增殖),对于研究微小残留病变检测和设计抗白血病独特型疫苗均有一定的意义。B-ALL病人外周血T细胞的TCR Vβ谱系呈现优势利用的特点,并存在克隆性增殖的T细胞,这可能是机体对白血病相关抗原产生的特异性免疫反应;Vβ21和Vβ23亚家族T细胞发生克隆增殖改变的趋向性比较明显,可能与B-ALL相关抗原刺激有关。T细胞株中检测到的肿瘤克隆其CDR3序列具有高度的特异性,是构建DNA疫苗的基础。

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