查询词典 Promoter

Pylori infection causes increased gastric mucomembranous cell proliferation by promoting expression of PCNA and inhibit gastric mucomembranous cell apoptosis by upregulating the level of bcl-2 protein expression, so HP might act as a tumor promoter in the genesis of gastric cancer.

同时又上调Bcl-2蛋白的表达水平而产生抑制凋亡的作用，从而在胃癌的形成中起到了一种促进剂的作用。

Effects of the pretreatment of catalysis, reaction temperature, the ratio of the reactants, the substrate-catalyst ratio and the content of the promoter on the reaction properties of NaK catalysts has been studied in a wide range.

本实验用超声波技术激活金属钾钠合金低共熔物催化剂，考察了催化剂预处理，反应温度，原料配比，催化剂用量以及加入助剂用量等因素对钾钠液态低共熔物催化剂上邻二甲苯与1，3-丁二烯合成OTP反应转化率的影响。

GUS expression activated by the OsGT1 promoter was strongly stimulated by NaCl and low temperature, moderately by abscisic acid and naphthaleneacetic acid, and not at all by salicylic acid and gibberellic acid.

表明水稻OsGT1基因主要在根和花中表达，与水稻抗盐与低温胁迫相关。

Both niobic acid and niobium oxide can be used as either catalyst,promoter or support in the heterogeneous catalytic reactions,such as selective oxidation,hydration,hydrolysis,alkylation,dehydrogenation and hydrogenation,because of their acidic and redox properties.

作为一种新型的催化材料，铌酸-氧化铌由于其独特的酸性和氧化还原性正受到越来越多人的关注。它可以作为催化剂的活性组分、助剂或载体使用，在烃类转化、选择性氧化、水解、水合、缩合、加氢脱氢等若干酸碱和氧化还原反应中得到广泛的应用。

As the bar gene is promoted by the CaMV35 promoter, in which there is a 19bp palindromic sequence could act as recombination hot spot and lead to DNA rearrangement, we presumed that the transgene recombination events happened during the integration course have generated the complex Southern patterns of bar gene expression cassette.

线形基因表达框的游离DNA末端和CaMV35S启动子中重组热点介导的转基因重组可能是导致bar基因表达框复杂整合的重要原因。

Pcr products were visualized under uv after agarose electrophresis. results: the hypermethylation of blu gene promoter was detected in all the 12 frozen tissue cases (100%) and 8 out of 35 paraffine embedded tissue cases (23%) by methylated primer and the hypermethylation of arf was observed in 1 of 20 frozen cases and 3 of 35 paraffine embedded cases.

结果：在12例鼻nk/t细胞淋巴瘤冰冻组织病例中，12例均有blu基因高度甲基化，仅1例有arf基因高度甲基化；35例石蜡组织病例中，blu基因高度甲基化8例，arf基因高度甲基化3例。

P16 gene is composed of two intervening sequences and three exons , and encodes p16 protein , which is the inhibiter of CDK4 and CDK6 . They can together prevent phosphorylation deactivation of pRB , and make the cell cycle blocked in G1 stage. P16 gene promoter region has a great of CpG islands , which can be methylated when some adverse factor appears , and so the genetic transcription of p16 can be inhibited , which leads to gene silencing, cell paraplasm, and tumor generate.

抑癌基因p16编码蛋白P16 ，是细胞周期蛋白CDK4和CDK6抑制剂，它阻止pRB磷酸化失活，使细胞周期阻滞于G1期。P16基因启动子区域富含CpG岛，当受到各种有害因素影响时，容易发生甲基化，从而抑制P16基因转录，导致基因沉默，细胞异常增生，导致肿瘤的发生[5]。

We expect that the transgenictomato plant become a bio-reactor and develop a new way to product wild-typep53 protein.In this study,the coding sequencing of human wild-type p53tumor suppressor was ligated with the promoter and terminator of phaseolin,which is expressed specially in plant seeds.

本实验试图将人野生型p53肿瘤抑制基因引入番茄植株，通过采收番茄果实很方便的获得p53蛋白，使转基因番茄成为p53蛋白的生物发生器，开辟一条生产p53蛋白的新途径。

Erve growth factor combined with its receptor, activated Ras - MAP kinase , mitogen - activated protein kinase kinase is the important regulating factor that make IkB kinase, IKK, phosphated, IkB kinase make the IκBα:(the subunit of NF -κB ) phosphated, the phosphated IkBα degraded, and p65 - p50 heterodimer can be formed, then the heterodimer translocated to nucleus and combined with the promoter domain or other consensus sequence.

GF与其受体相结合，最后可以激活Ras-有丝分裂激活的蛋白激酶途径，有丝分裂激活的蛋白酶激酶(MEKK1)是IγB激酶发生磷酸化的重要调节因子，IKK使NF-κB的亚单位IKBα发生磷酸化，磷酸化的IKBα发生降解，而最后留下p65-p50二聚体，该二聚体然后转位到细胞核内与κB基因的增强子区域或与他的顺式作用序列结合。

Moreoer, c-Fos and phospho–c-Jun protein expression was inhibited by PPARα agonists, indicating that PPARα ligands suppress OPN expression through negatie cross talk with AP-1–dependent transactiation of the OPN promoter.

另外，c-Fos及磷酸化c-Jun蛋白表达可被PPARα激动剂抑制，说明PPARα配体通过OPN启动子AP-1依赖型转录激活的负交互作用而抑制OPN表达。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。