查询词典 Promoter

In conclusion,this research has gotten some significant results:firstly Kail gene is highly related with the metastasis potential of colorectal carcinoma cells,secondly mutation of Kail gene,methylation of CpG islands in the promoter and abnormal expression of p53 have no important effects in the down-regulation of Kail gene.

本研究结果表明：Kai1基因与大肠癌细胞转移潜能有关；基因点突变、启动子CpG岛甲基化与p53异常在Kai1基因表达下调中不起重要作用。

The results indicated that Kail/CD82 is higher expressed in HT29 and SW480 than in LoVo and HCT116 whatever in mRNA or protein level.The possible mechanism of down regulation of Kail was also analyzed. By PCR-SSCP,8 exons of Kail,exon 3 to exon 10,were screened in LoVo and HCT116 cell lines. The methylation of CpG islands in promoter region was analyzed,and the expression level of p53 was detected by IH and Western Blot.

为进一步探讨Kai1基因表达下调的机制，本研究用PCR-SSCP技术分析了Kai1／CD82表达较低的LoVo与HCT116细胞系的Kai1基因第3～10外显子是否存在点突变，检测Kai1基因启动子区域CpG岛的甲基化状况，并用免疫组化与Western Blot等方法研究Kai1基因表达与p53异常之间的相关性。

The reaction between ketone and promoter was studied by using HPLC and GC/MS.

利用HPLC，GC/MS等分析手段研究了助催化剂与酮的相互作用。

He helped find a new promoter, and soon Kirkland returned to the ring and returned to form.

之后，科克兰德重上拳台，回到了正常轨道。

The promoter is typically haloarchaeal, but the start site of transcription is only seven bases from the 5'end of the initiator AUG codon, making the halC8 transcript another example of a"leadless transcript"in the haloarchaea.

它的-29～-24位置上是一"TATA"box序列，为典型的嗜盐古菌启动子；它的转录起始位点距离"ATG"只有7个核苷酸，也是典型的嗜盐古菌的"leadless transcript"。

Complementary sense promoter from cotton leaf curl virusis a novel promo ter and could direct high level expression of foreign genes in transgenic plants .

摘 要 棉花曲叶病毒互补链基因启动子是一种新近鉴定的启动子，它能驱动外源基因在植物体内高效表达。

The difference in the degree of lipolysis led by the variant of the promoter region of TNF-alpha may be one of the mechanisms for the variation in the degree of insulin resistance in general population.

该基因变异所导致的脂肪分解差异可能是群体中胰岛素抵抗程度变异的机制之一。

As for T〓 and T〓 generations of rolB-transformed plants under control of natural promoter, IAA contents increased significantly in leaves both under long-day and short-day, and in young panicles only under long-day.

2自然启动子调控的rolB转基因T〓和T〓代植株在不同光周期下叶片中和长日条件下幼穗中IAA水平明显高于对照植株，而短日条件下幼穗IAA水平却与对照水平相近。

Taken together, the survivin promoter appears to be a superior TSP for breastcancer targeting among them because it had high activity in established cell lines withlower variation and lower activity in liver.

总之，启动子CXCR4和Survivin在乳腺癌细胞系中具有特异的转录靶向性，腺病毒系统中启动子Survivin较CXCR4而言，在乳腺癌细胞中的变异小，而且在重要器官肝脏的活性仅为CXCR4启动子的1／87.46，提示其在乳腺癌基因治疗中具有更好的应用前景。

Deletion of PPARδ binding site located at -1245 to -1222 in the promoter region strongly reduced luciferase activity.

有趣的是，PPARδ的拮抗剂会降低iNOS的表现，因此我们假设iNOS的表现可能会受到PPARδ的调节。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。