查询词典 PIAS

PIAs are 'a process of ensuring that privacy concerns are identified at the early stage of an initiative so ...

PIA的是'一个过程，确保隐私问题上确定的早期阶段的一项倡议，使。。。

Simultaneously, according to different target proteins, these two mechanisms of PIAS proteins are not absolutely repulsive, which indicates the specificity and complexity of the function of PIAS proteins.

同时，针对不同的靶蛋白，PIAS蛋白的上述两种作用机制并不是完全互相排斥的，这体现了PIAS蛋白功能的特异性和复杂性。

A prototype system of the proposed approach, called PIAS (product innovation aiding system), has been implemented.

我们所提出的执行雏形系统叫作产品创新辅助系统(product innovation aiding system ；简称PIAS)。

Important family of negative feedback of JAK-STAT pathway: SOCS, PIAS, PTP is highly related with rheumatoid arthritis which will be the new ways for Clinical treatment, drug development and research of autoimmune diseases.

JAK-STAT通路负反馈调节的重要家族：SOCS、PIAS、PTP与类风湿关节炎高度相关，在未来可能成为自身免疫性疾病临床治疗、新药研发或科学研究的新途径。

There're three studies actually demonstrated the benefit in the patient population, the Bird data in Los Angles, Pias data and Peter Ferenshi data.

目前实际上已经有三个相关研究显示维持治疗有益患者抗病毒治疗效果，包括洛杉矶的 the Bird 研究数据、 Pias 研究数据和 Peter Ferenshi 研究数据。

By interacting with these proteins, PIAS proteins could affect their activation and function, and take part in gene transcriptional regulation and cellular signal pathway including Signal transducer and activator of transcription, Wnt, TGFβ, NF-κB pathways and so on, therefore present important biological functions.

通过相互作用，PIAS蛋白通过影响了蛋白的活性和功能，参与基因的转录调控和包括STAT(Signal transducer and activator of transcription)， Wnt， TGFβ， NF-κB等通路在内的细胞信号通路，具有重要的生理功能。

PIAS SUMO E3 ligases co-localize with and modulate SUMO modification of BRCA1, and are required for BRCA1 ubiquitin ligase activity in cells.

Morris等人发现，乳腺癌易感基因BRCA1（已知参与DNA损伤响应）产物的泛素连接酶活性，是在DNA损伤之后被由PIAS 调控的SUMO修饰激发的。

PIAS proteins play roles mainly through two mechanisms: acting as SUMO E3 ligases to promote modifications of some transcriptional factors and cofactors, especially sumoylation, and to regulate their transcriptional activation; acting as structural proteins to offer platforms for protein-protein interactions and to promote the abstraction and recruitment of other regulators in the cellular signal pathway complexes or gene transcriptional complexes, companied by the subnuclear location of target proteins.

PIAS蛋白的调控机制主要有两种：一种是通过其自身所具有的SUMO(small ubiquitin-related modifiers)E3连接酶活性，促进对一些转录因子、转录辅因子的化学修饰，尤其是SUMO化修饰，从而调控它们的转录活性；另一种是作为构架蛋白，为蛋白质之间的相互作用提供平台，促进细胞信号通路复合物或基因转录复合物中其它调节蛋白的去除和募集，并涉及到靶蛋白的亚核定位。

In this paper the thymus DNA of calf and the pBs plasmid are the main objects of our studies in ultraweak luminescence. By means of PIAS(Photon-counting image acquisition), ultraweak luminescence detector and Lambda Bio 40 of UV/VIS spectrophotometer, we studied the UL of DNA induced by the three oxygen free radicals: singlet oxygen Oa, hydroxy radical and superoxide anion(O2 ). We found that the OH can greatly increase the UL intensity of DNA.

本论文以小牛胸腺DNA和质粒pBs为实验材料，利用光子图像探测系统(Photon-counting image acquistion，PIAS)、微弱发光测量仪和UV／VIS分光光度计和生物统计学的成组比较法原理对单线态氧(~1O_2)、羟自由基、超氧阴离子(O_2~-)三种氧自由基诱导DNA超弱发光的变化过程进行了研究，结果发现这三种氧自由基中·OH能诱导DNA的超弱发光发生显著的增强变化，而其他两种氧自由基对DNA的超弱发光并无显著诱导作用。

There're three studies actually demonstrated the benefit in the patient population, the Bird data in Los Angles, Pias data and Peter Ferenshi data.

目前实际上已经有三个在这方面进行了相关研究，并且显示继续维持治疗有益患者抗病毒治疗效果的报告数据，包括洛杉矶的the Bird研究数据，Pias研究数据和Peter Ferenshi研究数据。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。