查询词典 Mycobacterium tuberculosis

Mycobacterium bovis is the causative agent of bovine tuberculosis in a range of animal species and human beings.

牛结核病主要是由牛分枝杆菌引起的一种人兽共患传染病。

Mycobacterium bovis BCG (Bacille Calmette-Guerin), the intradermally used tuberculosis vaccine, has been used all aroud the world for more than 40 years, and it is still the most commonly used human vaccine. In China, as a routine, all newborns are inoculated with BCG.

卡介苗作为结核病疫苗进皮内接种已经在全世界广泛应用四十余年，而且现在仍是人类使用最多的疫苗，在我国对新生儿仍进行常规接种。

Mycobacterium is the causive agent of tuberculosis in a range of human beings.

结核病主要是由分枝杆菌引起的一种传染病。

But people infected with the tuberculosis mycobacterium will not necessarily become sick.

但是感染了肺结核分支杆菌的人不是一定患病。

Polymarase Chain Reaction may be the better method of detecting M.tuberculosis than other methods and lead us to carry out a series of research on this problem. This thesis is composed of five parts:(1)systematic evaluation for the first time of the ability of five defferent PCR methods to detect M. tuberculosis;(2) using the endonuclease and southern blot by a radioactive and a nonradioactive labeled probe, to confirm the specificity of the PCR products and to analyse the sensitivity of detection by southern blot method using digoxigenin-labeled probe;(3) evaluation of acid-fast staining, bacterial culture and PCR for the detection of M. tuberculosis in sputum, pleural and peritoneal effusion samples;(4) The feasibility of PCR for detection of M tuberculosis on formalin-fixed paraffin embedded tissues;(5) 26 cases of sarcoidosis were retrospectively studiedwith PCR for M. tuberculosis and nontuberculosis Mycobacterium and the problems on histopatholoical diagnosis of sarcoidosis are discussed.

论文共分为五个部分，(1)首次系统地比较了五种不同引物序列的PCR检测结核杆菌方法的特异性和敏感性等情况；(2)利用限制性内切酶酶切分析和同位素及非同位素标记DNA探针进行Southern杂交的办法，分析PCR产物的序列与原设计是否相符及杂交检测PCR产物对提高检测结核杆菌敏感性的情况；(3)并对PCR用于快速检测临床标本中的结核杆菌进行了初步评价；(4)探讨了PCR用于检测石蜡包埋组织中结核杆菌的作用；(5)并利用PCR检测结核杆菌和非结核分枝杆菌的方法对26例原病理诊断为结节病的病例进行了PCR检测及组织病理学诊断的探讨。

aim: to establish a prediction strategy for mycobacterium tuberculosis (h37rv) secreted proteins to pave the way for further research. methods: the whole protome of h37rv was scanned by signalp and tmhmm. the protein date analysis system based on visual foxpro was established to process the output of signalp and tmhmm and identify the secreted proteins. the sequences of the secreted proteins were aligned by blastp.

以signalp和tmhmm两个软件对结核分枝杆菌蛋白组进行扫描，基于visual foxpro构建&蛋白质数据分析处理系统&对扫描原始数据进行分析处理以识别分泌性蛋白，再经blastp完成相似性比对。

Objective To discuss the assay methods and clinical value of IgG antibody to Mycobacterium Tuberculosis. Methods To detect the antibody levels of tuberculoprotein 16KDa, 38KDa and LAM by Protein Chip and ELISA together, the sensitivity, specificity and total coincidence rate of the two methods were compared.

目的 探讨结核分枝杆菌IgG抗体的检测及其临床应用价值方法应用蛋白芯片识别仪分析结核病人血清中结核菌蛋白16Kda和38Kda以及脂阿拉伯甘露糖抗体含量，同时与ELISA法进行比较，判断其敏感性、特异性和总符合率。

Arising from the combination of Mycobacterium tuberculosis is a zoonotic infectious diseases.

结核分枝杆菌引起的结核病是一种人畜共患的传染病。

MS detection showed the six protein spots were inorganic pyrophosphatase, peptidyl-prolyl cis-trans isomerase A, elongation factor Tu, unnamed protein, dioxygenase and moxR protein. Conclusion Protein expression differences were discovered between multi-drug-resistant Mycobacterium tuberculosis isolate and drug-sensitive isolate.

质谱分析发现，6个蛋白质点分别代表的蛋白质为无机焦磷酸酶、多肽脯氨酰基顺反同分异构酶A、延伸因子Tu、420个氨基酸的未知功能蛋白质、双加氧酶和转录调节蛋白。

Methods Th multi-epitope peptide was made up of 5 Th epitopes(heat shock protein 65 of Mycobacterium tuberculosis p1-20,E2 protein of Rubella virus p54-65,engineering epitope PADRE,heat shock protein 60 of Chlamydia trachomatis p35-48,and tetanus toxin p830-843),and its gene sequence including of 219bp.

方法复合T辅助细胞表位由5个T辅助细胞表位组成(结核杆菌热休克蛋白65p120、风疹蛋白E2-4p5465、人工合成T辅助细胞表位PADRE、沙眼衣原体热休克蛋白60p3548、破伤风类毒素p830843)，其基因序列由219个核苷酸组成。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。