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Methods Forty-eight patients (50 eyes) with diffuse diabetic macular edema were randomly divided into two groups: twenty-five eyes were treated with an intravitreous injection of triamcinolone acetonide (4 mg/0.1 ml), and another twenty-five were treated with a peribulbar injection of triamcinolone acetonide (40 mg/1 ml).

将48例（50眼）弥漫性黄斑水肿患者随机分为曲安奈德玻璃体腔（0.1 ml，4 mg）注射目的总结曲安奈德(triamcinolone acetonide，TA)联合黄斑部格栅样光凝对糖尿病性黄斑水肿的疗效，评估TA的两种不同给药方式的安全性。

At the IV dose of 20 and 30 mg/kg, Aloin and Isobarbaloin result appear the mean terminal eliminate half-life（T1/2 β）were 54.1±28.4; 28.7±18.3 and 36.9±21.9;49.7±17.1 min, respectively. The mean area under the serum concentration curve（AUC0-∞）were about 411.655± 13.027;318.213±19.924 and 701.336±116.631;573.278± 86.870μg min/mL, respectively. The mean drug clearancewere 0.165±0.011;0.214±0.016 and 0.149±0.030;0.182±0.035 L/min, respectively.

若静脉注射剂量20和30 mg/kg后，其芦荟大黄苷及异芦荟大黄苷分别平均末端排除半衰期（T1/2 β）为54.1±28.4；28.7±18.3和36.9±21.9；49.7±17.1 min，平均稳定状态分布体积为7.668±3.155；6.343±3.522和5.146±2.490；8.525±2.683 L，平均曲线下面积（AUC0-∞）为411.655 ±13.027；318.213±19.924 和701.336±116.631；573.278±86.870 μgmin/mL，平均血浆中药物最高浓度为23.920±5.669；30.442 ±7.537和57.920±27.690；36.373±14.174 μg/mL，平均药物之清除率为0.165±0.011；0.214±0.016和0.149±0.030；0.182±0.035 L/min。

At the IV dose of 20 and 30 mg/kg, Aloin and Isobarbaloin result appear the mean terminal eliminate half-life（T1/2 β）were 54.1±28.4; 28.7±18.3 and 36.9±21.9;49.7±17.1 min, respectively. The mean area under the serum concentration curve（AUC0-∞）were about 411.655± 13.027;318.213±19.924 and 701.336±116.631;573.278± 86.870μgE min/mL, respectively. The mean drug clearancewere 0.165±0.011;0.214±0.016 and 0.149±0.030;0.182±0.035 L/min, respectively.

若静脉注射剂量20和30 mg/kg后，其芦荟大黄苷及异芦荟大黄苷分别平均末端排除半衰期（T1/2 β）为54.1±28.4；28.7±18.3和36.9±21.9；49.7±17.1 min，平均稳定状态分布体积为7.668±3.155；6.343±3.522和5.146±2.490；8.525±2.683 L，平均曲线下面积（AUC0-∞）为411.655 ±13.027；318.213±19.924 和701.336±116.631；573.278±86.870 μgEmin/mL，平均血浆中药物最高浓度为23.920±5.669；30.442 ±7.537和57.920±27.690；36.373±14.174 μg/mL，平均药物之清除率为0.165±0.011；0.214±0.016和0.149±0.030；0.182±0.035 L/min。

And (20. 5 ± 1.7) ml· 100 g-1 ·min-1, respectively. When compared in 3 groups, the temporal and parietal lobe rCBF had a decreasing tendency in aMCI group, while in VCI-ND group, the most dominant decreasing parts were mainly concentrated in white matter region (17. 7±2. 3 ml·100 g-1·min-1, F = 5. 740, P = 0. 002. Whatever the depth or the width was, beth periventricular and subeortical deep white matter, anterior and posterior ventricular regions were all involved. There are no dominant difference of rCBF in caudate nucleus, lentiform nucleus and thalamus.

2NC组、aMCI组和VCI-ND组患者的rCBF表现比较：aMCI组颞、顶、枕叶的rCBF值呈一定趋势的减少，VCI-ND组额叶的rCBF值呈一定趋势的减少，而VCI-ND组rCBF下降最明显的部位集中在白质区域[(17.7±2.3)ml·100 g-1·min-1，F=5.740，P=0.002]，从深度看覆盖了脑室旁白质和皮质下深部白质两部分，从长度看覆盖了白质的前后区域。3组基底节区核团包括尾状核、豆状核和丘脑的rCBF值比较差异无统计学意义。

MIC of JS399-19 inhibited mycelial growth of 52strains of E moniliforme was 20μg/ml.

氰烯菌酯对52个F.moniliforme菌株菌丝生长的MIC值20μg／ml，抑菌生长的EC_(50)值为0.2603±0.0541μg/ml。

Methods Mononuclear cells of peripheral blood were isolated by Ficoll Hypaque centrifugation from 32 breast cancer patients and plated on 6-well culture plates(106 /ml, 2 ml/well) in RPMI1640 medium supplemented with 10％ heat-inactivated fetal bovine serum, GM-CSF, IL-4, and/or TNF-α. Two h later, nonadherent cells were gently removed and fresh medium was added.

方法采用密度梯度离心的方法，分离32例乳腺癌患者外周血中的单个核细胞，在6孔培养板上(106/ml，2ml/孔)，用含10％热灭火的小牛血清和GM-CSF、IL-4、TNF-α细胞因子的RPMI 1640培养基培养。

Results showed that, pyrolin had obvious action on two species of fungi, and the antifungal effect was positively correlative with concentration. The EC50 was 0.4076 mg/mL and 0.4626 mg/mL respectively after cultured 3 days. The main antifungal period was the fast growth period of fungi, and lead to it lag behind. Observation under SEM revealed that pyrolin caused a series of marked morphological and structural alterations of hyphal. These changes included mutual adhesion of mycelium, the hyphal was irregular in diameter, local denting, some of mycelium was broken, disruption of cell wall, outbreaking of inner cytoplast, and the empty cavity appeared. As a result, pyrolin restrained the growth of these fungi.

结果表明，鹿蹄草素对上述两种真菌均具有明显的抑制作用，抑菌效果与浓度呈正相关，培养3d时的EC50分别为0.4076、0.4626 mg/mL；抑菌时期主要是在真菌的快速生长期，使其快速生长期滞后；扫描电镜显示，鹿蹄草素作用下菌体形态发生异常变化，表现为菌丝体之间相互粘连，菌丝粗细不均匀，细胞壁破裂，局部凹陷，部分菌丝断裂，大量内容物外溢，出现空腔等现象，从而发挥其抑菌作用。

Thirty minutes later intubation of pancreaticoduodenal artery was done and 3.6 ml of 0.5% CaNa2 EDTA were infused.

动脉灌注磷酯酶A2抑制剂质量浓度为0.5%的CaNa2 EDTA 3.6 ml，并与不治疗组、区域灌注生理盐水组及外周用质量浓度为0.5%的CaNa2 EDTA 3.6 ml 3组对照。

Pelargonic acid vanillylamide had a good linearity in the range of 1.967～39.34 μg/mL with average recovery of 100.8% and RSD of 1.3%.

结果 马来酸氯苯那敏在19.96～399.22 μg/mL范围内线性关系良好，平均回收率为100.0%，RSD为1.2%；壬酸香蓝酰胺在1.967～39.34 μg/mL范围内线性关系良好，平均回收率为100.8%，RSD为1.3%。

After ketamine and compound chlorderazin were intramuscularly injected according to 25 mg/kg. constrast medium of Omnipaque 300 mgI/ml （dosage 2.6 ml/kg/weight） was injected into the postauricular central vein.

按25 mg/kg氯胺酮加复方氯丙嗪针肌注麻醉后，经耳后中央静脉穿刺注射非离子型对比剂（Omnipaque 300 mgI/ml）。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。