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The results of bioassay indicated: 1 The new compound (compound 6) and other three compounds (compound 1, 2 and 5) showed strong anti-HIV activity (EC50.064μg/ml), compound 3 and 4 showed less activity (EC50=6.18μg/ml and 12.85μg/ml respectively); Compound 5 and 6 showed weak cytotoxicity, and compound 1-4 showed moderate cytotoxicity; 2 Compound 5 and 6 were activated to all the four tested microbial; Compound 1, 2 and 13 were activated to all the three tested bacterial, but were unactivated to the tested fungi, Penicillium avellaneumUC-4376; One of the test bacterial, Staphylococcus aurues, seemed to be sensitive to all the eleven triterpenoids.
新化合物(化合物6)和化合物1、2、5具有强烈的体外抗HIV活性,其EC50值均小于0.064μg/ml,化合物3和4也具有抗HIV活性,但活性相对较弱,EC50值分别为6.18μg/ml和12.85μg/ml;化合物1-6都具有一定的细胞毒性,且化合物5和6的细胞毒性明显弱于化合物1-4的。 2)新化合物(化合物6)和化合物5对所有四种试验菌都有一定的活性;化合物1 、2和13对三种细菌均有一定的活性,但对真菌橙色青霉UC-4367(Penicillium avellaneum UC-4376)无活性;金黄色葡萄球菌对所有11个三萜都较为敏感。
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Results When resident infusion is about 500 ml at that day,it's good time to cease catheter and the urocyst capacity measured is about 379 ml and actual urinary output is about 390 ml.
结果 在患者术后当日输液余量约为 5 0 0ml时,为拔除尿管的最佳时机,此时测定并计算出的膀胱容量约为 379ml,实际尿量约为 390ml。
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Then Vero cells were inoculated with a final cell density of 1×105/mL . After 7 days of culture, cell density can reach 6~7×106/mL, then rabies virus VaG strain was inoculated with a MOI of 0.01. After 24h inoculation, the cultured viruses were harvested continuously for 12 days. The titer of collected virus in the culture medium was about 6.0 to 8.5 logLD50/mL. From these collected viruses, vaccines were prepared through the steps of concentration, inactivation and purification, The quality of these vaccines meets "The Chinese Requirements for Biologics Year 2000".
在5L体积的生物反应器中,加入含10g/L微载体的199培养基,接种Vero细胞至细胞浓度达到1×105/mL,培养7d后细胞可生长至6~7×106/mL,然后以感染复数为0.01接种狂犬病毒VaG株,接毒后24h开始收获,连续收获12d左右,收获的病毒滴度范围在6.0~8.5logLD50/mL,收获的病毒原液经浓缩、灭活和纯化等步骤制备成疫苗,各项质量指标均达到《中国生物制品规程》2000年版要求。
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The inhibition effect of chloroform fraction was the most potent, with the inhibition rate about more than 83% to 5 plant pathogenic fungi under the concentration of 15mg/mL. Under the concentration of 15mg/mL, the ethyl acetate fraction and n-butanol fraction thoroughly inhibited the growth of Alternaria solani and Valsa mali, with the inhibition rate up to 100%. The n-butanol fraction showed the highest potent virulence, with EC50 to Alternaria solani and Valsa mali about 0.09 and 0.279 mg/mL respectively.
其中氯仿部分的抑菌效果较好,当质量浓度为15mg/mL时,其对5种植物病原菌的抑制率均在83%以上;15mg/mL乙酸乙酯部分和正丁醇部分分别对番茄早疫病菌和苹果腐烂病菌有强烈且稳定的抑制作用,抑制率达100.00%,正丁醇部分对这两种菌丝生长抑制毒力最好,EC50分别为0.090和0.279mg/mL。
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The bioassay indicated that some of them possess certain fungicidal activity against Botrytis cinerea, Gibberlla zeae, Rhizoctonia solani, Venturia nashicola at a dose of 50 μg/mL. The EC50 value of title compounds B-8、B-9、B-10、B-12 was reached 1.0, 0.2, 1.2 and 0.4 μg/mL against B. cinerea, the effect was approximated or better than pyrimethail and EC50 value of title compounds B-8, B-10, B-11 was reached 0.07, 0.2 and 0.05 μg/mL against G. zeae, the effect was better than carbendazim.
在50μg/mL浓度时,该系列化合物对番茄灰霉病菌Botrytis cinerea、小麦赤霉病菌Gibberlla zeae、水稻纹枯病菌Rhizoctoniasolani、梨黑星病菌Venturia nashicola菌丝生长均具有很好的抑制活性,其中化合物B-8、B-9、B-10、B-12对番茄灰霉病菌的EC50值分别为1.0、0.2、1.2、0.4μg/mL,接近或优于对照药剂嘧霉胺,B-8、B-10、B-11对小麦赤霉病菌的EC50值分别为0.07、0.2、0.05μg/mL,优于对照药剂多菌灵。
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After light radiation time of one hour,the IC50 of cytotoxicity of C60 liposomes is 154.9 μg/ml.During the concentration of C60 liposomes are 16.86 μg/ml and 33.72 μg/ml separately,the plaque reduction rate of direct virucidal activity to HSV-1F strain is positive correlation to the time of light radiation,the correlation coefficients rate 0.8510(P.005) and 0.9766 (P.005) respectively.
光照1 h,C60脂质体对Vero细胞的细胞毒为154.9 μg/ml.C60脂质体浓度为16.86 μg/ml及33.72 μg/ml时,对HSV-1F株直接杀灭的空斑减数率与光照时间成正相关,相关系数r分别为0.8510(P.005)和0.9766(P.005);当C60脂质体浓度为16.86 μg/ml时,对HSV-1F株感染阻断的空斑减数率与光照时间正相关,相关系数r依次为0.84(P.005)及0.9923(P.005),说明C60的抗病毒作用具有时间效应,主要是光敏动力学机制起作用。
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Although aqueous extract of Andrographis paniculata, aqueous extract of Mesona chinensis, ethanolic extract of Verbena officinalis at 1.25 μg/mL could only decrease TBARS formation, and ethanolic extract of Glossogyne tenuifolia, ethanolic extract of Mesona chinensis only decreased carbonyl formation at 1.25 μg/mL, ApW, McW, VoE, GtE and McE at 5 μg/mL appeared to have a lengthening in lag phase.
虽然,1.25 μg/mL 穿心莲水萃取物、仙草水萃取物、大陆马鞭草乙醇萃取物只能减少TBARS 的形成,而1.25 μg/mL香茹乙醇萃取物、仙草乙醇萃取物 McE)只能减少蛋白质羰基(carbonyl groups 的形成,但在5 μg/mL 的ApW、 McW、 VoE、 GtE 和McE 可明显延长迟滞期。
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Methods 24 patients known to suspect of having pulmonary embolism underwent MCTPA with 20 ml contrast medium. Scanning delay time was adjusted by using a test bolos. Contrast medium injection rate was 5.5 ml/s. The time of imaging data acquisition was 2-3 s. In addition 24 patients undergoing MSCTPA with 50 ml contrast medium were included in control group. Imaging quality was evaluated by five degree with blind method.
应用多层螺旋CT对24名疑似肺栓塞的病人行CTPA检查,对比剂总量为20 ml(300 mgI/ml),以单层动态增强扫描所测时间-密度曲线的峰值时间为扫描延迟时间,对比剂注射速率5.5 ml/s,数据采集时间2~3 s;另随机选择24例常规对比剂剂量(50 ml) CTPA检查影像作为对照组,影像质量按5级行盲法评价。
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Methods Ninety ASA Ⅰ~Ⅱ patients undergoing UPPP surgery were randomly divided into three groups: F group (fentanyl 10 μg/kg), FL group (fentanyl 5 μg/kg + lornoxicam 0.4 mg/kg), or TL group (tramadol 5 mg/kg + lornoxicam 0.4 mg/kg). The drugs were diluted with normal saline to 100 mL (background 2 mL/h, PCIA bolos 1.5 mL, lockout time 15 min).
90例择期行UPPP的阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea, syndrome, OSAS,即鼾症)患者,ASAⅠ~Ⅱ级,随机分为3组(n=30),F组:芬太尼10μg/kg;FL组:芬太尼5μg/kg+氯诺昔康0.4mg/kg;TL组:曲马多5mg/kg+氯诺昔康0.4mg/kg;每组镇吐药物均为氟哌啶5mg,均以生理盐水稀释至100mL,背景剂量2mL/h,PCIA1.5 mL/次,锁定时间15min。
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Methods sd rats were used to make hemorrhagic shock model by 45% hemorrhage. effects of 4 ml/kg, 6 ml/kg and 8 ml/kg of hsd on blood gas were observed. twice volumes of lactated ringer's were used as control.
采用sd大鼠45%重度失血性休克模型,观察4 ml/kg,6 ml/kg 和8 ml/kg 7.5%的高渗氯化钠/6%的右旋糖酐复苏对失血性休克大鼠血ph值,二氧化碳分压(pco2),氧分压(po2)的影响,以2倍失血量的乳酸林格氏液做对照。
- 相关中文对照歌词
- Gods Don't Chill
- Lord Have Mercy
- Avant De Partir
- Turn Around (5, 4, 3, 2, 1)
- Marche Ou Crève
- Wat Da Hook Gon Be
- Heaven For A Gangsta
- Cocoa Leaf (No Relief)
- Hear Me Coming
- 推荐网络例句
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The work of this paper is as follows: 1. Looking back the progressing history of the linear motor, introducing the features of the elevator driven by linear induction motor, radicating the topic of this paper "the digital frequency variable control of the elevator bi-side direct driven by linear induction motor". The research of this paper covers the conventional VVVF control, space vector based VVVF control, vector control and DTC.
本文主要开展了以下几个方面的工作: 1 回顾了直线电机发展历史,电机的驱动技术演变,特别是针对直线电机的驱动,简要介绍了直线感应电机驱动电梯的优点和不同结构类型,对传统的v/f控制,基于空间矢量法的v/f控制,矢量控制,和基于电压空间矢量的直接转矩控制进行了比较,确立了本课题的研究主题:直线感应电机双边直推式驱动电梯的全数字变频控制。
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The article combines with the treatment of a superficial civil air defense work to introduce how the grouting method to improve the performance of the backfill soil.
文章从治理漂浮人防工事的角度提出了注浆技术在改善回填土性质方面的应用,并详细阐述了注浆技术的施工流程。
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I knew nor shyness nor fear, my life was boisterous.
我不懂得羞怯和惧怕,我的