查询词典 Lys

FITC can inhibit the antimonite-stimulated ATPase activity of ArsA and a combination of ATP and antimonite can completely protect ArsA from the inactivation of FITC. The Lys residue in the glycine-rich loop in ArsA is possibly one of the sites for FITC modification. Antimonite can induce the fluorescence resonance energy transfer between FITC and TRITC that separately labeled on different ArsA molecules.

研究还发现FITC对ArsA的ATP酶活性有抑制作用，ATP和SbO〓与ArsA的结合完全拮抗这种抑制，说明ATP和SbO〓与ArsA的结合能够引起ArsA产生一种完全不同于它们单独与其结合时的构象变化，从而使ArsA上FITC的修饰位点变得不易接近，同时ATP结合位点内的Lys可能是FITC在ArsA上的结合位点之一。

Several coterminous bands could be observed by PAGE of natural Eisenin Ⅰ and several coterminous peaks of Eisenin Ⅰ were also detected with MALDI-TOF-MS when the molecular weight of three main peaks are 24, 645, 25, 052 and 25, 281, separately. The amino acid composition of Eisenin Ⅰ(pI. 8) is specilized with high content of acidic amino acids and low content of alkaline amino acids; At the same time, the content of Ser and Thr are quite high and that of Lys, Met, Phe and Trp are quite low. Eisenin Ⅰ is highly homologous with serine proteases. Then, by fibrin plate assay, Eisenin Ⅰ was identified to be a plasmin and also a plasminogen activator, and the fibrinolytic activity was inhibited by PMSF (an inhibitor of serine proteases).

赤子素Ⅰ氨基酸组成特点为高的酸性氨基酸和低的碱性氨基酸含量，且Ser、Thr含量高而Lys、Met、Phe和Trp含量很低；等电聚焦电泳测得其等电点pI.8.N端序列比较结果显示赤子素Ⅰ与丝氨酸蛋白酶类高度同源，纤维蛋白平板法测得赤子素Ⅰ同时具有纤溶酶和纤溶酶激酶活性；通过PMSF对赤子素Ⅰ纤溶酶活性的抑制实验证明，赤子素Ⅰ属于丝氨酸蛋白酶类。

Objective To establish a prokaryotic expression system for expressing mouse enterokinase which could recognize and cut the sequence of4-Lys in order to provide a technique platform for application of recombinant enterokinase.

目的：制备能在原核表达系统中表达并特异性识别4-Lys序列的鼠源性肠激酶，为推广应用重组肠激酶提供技术平台。

The diet containing feather meal is known to be deficient in His, Met, and Lys.

包含羽毛一餐的饮食被知道是不足的在他，遇见，和 Lys。

The relationship between the Z value and bioactivity recovery of Lys with different urea concentrations was also investigated.

还对不同脲浓度条件下Lys的活性回收率与Z值之间的关系进行了研究。

Its activity of SOD and GSH-PX have no significant changes, while its SA and LYS are significant higher than before intervention.

在试验过程中，试验组的COMET和MDA降低，SOD和GSH-PX活性无显著性变化，SA和LYS显著升高。

The optimization of chromatographic conditions for obtaining the high recoveries of both mass and bioactivity of Lys was investigated in detail.

为了提高Lys的质量及活性回收率对所用色谱条件进行了优化研究，当蛋白起始浓度为20.0mgmL^(-1)时，Lys的质量回收率和活性收率分别为97.8%和95.4%。

To synthesize the octreotide, Phe-Leu-Glu-Glu-Leu and C_(15)H_(31)-CO-Lys-Thr -Thr-Lys-Ser peptides, the strategies are as followings: Fmoc- group as protective group for α-NH_2; TBTU, DIEA and HOBt as coupling reagent; and ethanedithiol -phenol - thioanisole - H_2O - TFA ( 2.5:5:5:5:82.5 , V/V ) as cleaving solution.

采用Fmoc固相合成法，以苯并三哗四甲基脲四氟硼酸盐、二异丙基乙胺和1-羟基苯骈三氮唑为缩合剂；苯酚—乙二硫醇—苯甲硫醚—水—三氟乙酸(5：5：2.5：5：82.5，V/V)为切割试剂，合成了奥曲肽、Phe-Leu-Glu-Glu-Leu及C_(15)H_(31)-CO-Lys-Thr-Thr-Lys-Ser三种小分子多肽，并对奥曲肽的合成规模进行了放大。

Second, residues in the reactive site of the inhibitor were replaced by the consensus substrate recognition sequence of furin, namely, Arg at P_1, Lys at P_2, Arg at P_4 and Arg at P_6. In addition, the P_7 residue Asp was substituted with Ala to avoid possible electrostatic interference with furin inhibition. Finally, the extra N and C terminal residues beyond the doubly conjugated disulfide loops were further truncated. However, all resultant synthetic peptides were found to be temporary inhibitors of furin and kexin during a prolonged incubation, with the scissile peptide bond between P1 and P'1 cleaved to different extents by the enzymes.

高活性、低分子量的furin酶抑制剂有可能发展成为新型的抗细菌内毒素和抗病毒感染的药物，我们以绿豆胰蛋白酶抑制剂Lys片段长链22肽为模板，设计了一系列能抑制furin和kexin活性的突变体，采用如下三种方法逐步优化：一、去除Lys片段长链三对二硫键中的一对，用Ser替换Cys，减少可能存在的二硫键错误配对；二、抑制剂的活性中心根据furin底物的专一性逐步改变，即P1、P2、P4和P6位分别变为Arg、Lys、Arg和Arg，同时为了避免P7 Asp和P6 Arg之间可能存在的相互作用，将P7位Asp替换为Ala；三、将两对二硫键形成的双环的外面5个氨基酸残基去除。

Thymosin 1（Tα1） is a acidic protein composed of 28 amino acid residues with isoelectric point 4.2 and molecular weight 3102.Its amino acid sequence is: N-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu -Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-C. T1 is a T-cell potentiating factor.

胸腺素α1（thymosin 1，Tα1）是由28个氨基酸组成的酸性多肽，等电点4.2，相对分子量3108，其氨基酸序列为：N-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-C[1，2]。Tα1具有多种免疫活性，可以促进T淋巴细胞的成熟和分化，促进成熟的T细胞、自然杀伤细胞分泌各种细胞因子如IL-2、INF-α等，同时也促使高亲和力白介素-2受体的生成[3-10]。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。