查询词典 LM

Atural killer cells promote CD8 Tm cell generation by regulating the extent of contraction.To generate CD8Tm cells,we adoptively transferred Thy-1.1 OT-I CD8 T cells in to host C57 mice(Thy-1.2) followed by injection of a virulance attenuated stain of Listeria Monocytogenes(ΔactA LM-OVA)via the tail veil 24h later.

K细胞通过调节初次应答收缩期而促进CD8Tm细胞产生为诱导产生CD8Tm细胞，我们将Thy-1.1~+ OT-I TCR转基因小鼠的CD8 T细胞通过尾静脉注射过继回输到野生型C57小鼠(Thy-1.2)体内，24h后通过尾静脉注射表达OVA的李斯特菌毒力减弱株(△actA LM-OVA)进行感染。

The study showed the recombinant wt/mCREG protein depressed the VSMC proliferation depending on dose and the optimal concentration was 400nM;2biologic function of CREG protein and the membrance receptor mechanism:①effect on VSMC migration: the wound healing experiment showed the OB2 cells migration was slower significantly after added wt/mCREG(400Nm) in supernatant. The HITASY cells migration were very slowly and no remarkable change. The gelatinase digestion and Western blot analysis showed the matrix metalloproteinase was decreased and TIMPs was increased;②effect on differentiation: after added wt/mCREG(400nM), the expression of myocardin, SMα-actin, MHC and caldesmin were increased and that of LM-1 and FN were decreased in OB2 cells. These effects were more significant when adding wtCREG.;③effect on VSMC proliferation: Cell cycle assay and BrDU stain showed: after added the wtCREG and mCREG protein, the ratio of cell in G0/G1 phase increased to 0.5773 and 0.5572 from 0.5308 respectively in OB2 group, which increased to 0.7369 and 0.7034 respectively from 0.6297 in HITASY group;3Role of M6P/IGF2R in CREG biologic function:①ELISA and co-immunoprecipitation showed the wt/mCREG binding to M6P/IGF2R directly.②antibody blocking test: when the anti-IGF2R was added to medium at the same time with wt/mCREG at different concentration(2μg/mL、4μg/mL、8μg/mL),the effects of CREG protein which depressing proliferation, migration, secretion and promoting differentiation were blocked, which had the positive correlation to the concentration of added anti body. The studies showed two combinant CREG promoted VSMC switch to differentiation phaenotype, at the same time, depress VSMC proliferation, migration and secreting extracellular matrix.

上述实验结果证实：两种重组CREG蛋白对VSMC增殖均有剂量依赖性的抑制作用，并且相同浓度的糖基化的CREG蛋白对细胞增殖的抑制效应更为显著，最佳效应浓度为400nM；2两种重组CREG蛋白添加后对HITASY和OB2细胞生物学行为的影响：①CREG蛋白对VSMC迁移的影响：刮伤实验发现，加入最佳效应浓度的wtCREG和mCREG蛋白24h后，OB2组迁移能力下降，HITASY组无明显变化；细胞外基质金属蛋白酶-2，9(Matrix metallo-proteinase 2，9，MMP2 ，9)明胶酶电泳检测和Western blot检测结果证实，两种CREG蛋白均可以使OB2细胞合成细胞外基质MMP2，9减少，而组织金属蛋白酶抑制物(Tissue Inhibitors of Metalloproteinases，TIMPs)增加；②CREG蛋白对VSMC分化的影响：加入400nM的wtCREG和mCREG蛋白12h后，OB2细胞myocardin、SMα-actin、MHC、caldesmin表达增加，LM-1、FN表达减少；③流式细胞仪分析细胞周期和BrDU染色分析证实，加入400nM的wtCREG和mCREG蛋白后，OB2组G0/G1期细胞由0.5308分别增加至0.5773和0.5572，HITASY组G0/G1期细胞由0.6297分别增加至0.7369和0.7034；3M6P/IGF2R在重组CREG蛋白的生物学功能中的调控作用：①免疫共沉淀和免疫荧光双染色分析结果显示，CREG蛋白与M6P/IGF2R存在直接结合；②应用抗体阻断实验：将不同浓度的anti- M6P/IGF2R(2、4、8μg /mL)与两种CREG蛋白同时加入培养液中，CREG蛋白抑制VSMC增值、迁移和合成细胞外基质、促进分化的效应减弱，而且与加入anti- M6P/IGF2R浓度正相关。

The foodbome origin LM strains are different clones which are distributed diffusedly in Hangzhou.

杭州市食品中LM的污染来源于不同的克隆株，菌型分散，未发现单个基因型菌株流行的迹象。

METHODS: To construct recombinant expression plasmid subtype H1 of SIV HA gene of A/Swine/Guangdong/LM/2004(H1N1).BALB/c mice of 6-8 weeks old were immunized endemically with the recombinant plasmid.The splenocytes from the immunized mice were fused with Sp2/0 myeloma cells after the last immunization.

构建 H1 亚型猪流感病毒A/Swine/Guangdong/LM/2004(H1N1)HA基因表达质粒，基因免疫6～8周龄雌性BALB/c小鼠，加强免疫后取其脾细胞与骨髓瘤细胞 Sp2/0进行融合。

Different types of sample need different culturing and one eyen needs two or more than two methods when necessary to increase the detecting rate of Lm in the PCR rapid detection.

不同样品类型要用不同的增菌法，必要时用2种以上力法相结合，提高食品中Lm的检出率。

Among them, the long term interest rate is chosen as the intermediary target by Keynes school, and money supply chosen by Monetarism, the interest rate chosen by horizontalism with consideration that the interest rate elasticity of the monetary demand is very high, and William Poole thinks that the choice of intermediary s targets must depend on two factors: First is which is more unstable between the actual economy and money. Second is the slope of IS and LM curve.

现将每章的主要内容分述如下：论文第一章对货币政策中介目标国内外的理论作了一个研究综述，提出理论界在选择货币政策中介目标方面的不同观点，其中国外有：凯恩斯主义认为应将长期利率作为中介目标，货币学派认为应将货币供应量作为货币政策的中介目标，普尔认为中介目标的选择必须取决于两个因素：一是实际领域和货币领域哪个部门更不稳定，二是IS和LM曲线的斜率；水平主义理论主张，在货币需求的利率弹性很高的前提下，利率也就成为货币政策的中介目标。

Including MPS, MBF, RP, HP, LM, E-type, such as the roll grinding mill, Mopan, Central and ball mill, cement mill in the liner, Bi board, at Wharf board, fans of the impact plate mill And the liner, and so on.

主要包括MPS、MBF、RP、HP、LM、E型等磨机的磨辊、磨盘、磨环及磨球，水泥磨中的衬板、萞板、隔仓板等，风扇磨中的冲击板及衬板等。

The effect of Ruscogenin glycoside (Lm-3), isolated from Liriope muscari, on T cell adhesion to ECM was investigated in the last chapter.

第五章主要探讨了Lm-3对T细胞与ECM粘附这一靶点的作用及其机理。

2Myocardial ultrastructure was normal in the control group,myoneme arranged disordered,the structure of typical sarcomere disappeared, mitochondrium intumesced,interstitial substance fiber hyperplasy,capillary vessel endothelial cell swelled in DG group.Myocardial ultrastructure improved slightly in rats of SM and LM groups. 3NF-κB p65 and COX-2 had a small quantity to present in the myocardium tissue of control group,while the quantity increased obviously in the diabetic group.The level of it in the group of treatment was significant lower than that in the diabetic group.There was significant difference between the two groups. Conclusion Metformin can protect against the heart injury in diabetic.

结果 1与对照组比较，DG组体重明显减轻，血糖、心脏质量指数、INS、TG、T-CH及FFA明显升高(P＜0.01)；应用 MT治疗后体重无明显增加，INS有所下降，心脏质量指数、血糖、TG及FFA明显降低(P＜0.01)；DG组心肌组织MDA明显升高，SOD明显降低(P＜0.01)，MT治疗后上述指标明显改善；2超微结构观察单纯糖尿病组肌丝结构明显紊乱，典型肌小节结构消失，线粒体肿胀、间质纤维增生，微血管内皮细胞肿胀等表现，而SM及LM组可见组织结构有所改善；3对照组心肌NF-κB p65及COX-2只有少量表达，单纯糖尿病组表达量明显增多(P＜0.01)，MT治疗后表达量明显减少(P＜0.01)。

The static time and temperature's drift of the quartzose flexible accelerometer in SINS was studied through theory and experiments,and a LM algorithm's BP network was developed to compensate the drift.

针对捷联惯导系统中石英挠性线加速度计输出偏值在快速启动和不同温度条件下漂移较大的问题，从理论和大量试验上研究了其静态时、温漂特性，提出了采用LM算法的BP神经网络进行二维补偿的方法。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。