查询词典 IL

In summer of the result of the experiment, we can suspect the traditional Chinese medicine BaoTai Decoction may urge Th2 cytokine (IL-4, IL-10)'s express level to increase and Th1 cytokine (IL-12, IFN-γ)'s express level to decrease through adjusting Th cell's network equibrium, then prohibit maternal -fetal immune system to assault Fetus, which is good to maintenancing cyesis.

综合本实验结果，推测中药保胎汤可能通过双相性调节母-胎界面Th细胞网络的平衡，促使保护母-胎免疫功能Th2型细胞因子（IL-4，IL-10）增加，损伤母-胎免疫Th1型细胞因子（IL-12，IFN-γ）抑制，从而阻止母胎免疫系统对胎儿的攻击，利于妊娠维持。

Results: IL-8 protein was located in the epithelium of viii. The expression of IL-8 was significantly increased in RSA group than that in the control group. Positive IL-8 cells was shown in decidua of RSA group, and its IL-8 level was higher than that in the control group. By hematoxylin-eosin staining. trophoblastic layer was found to get thinner, cells of trophoblastic layer denatured or necrotized, and turned acidophily, and the fibration of villous axis increased in RSA; decidual cells lost connection, a part of decidual cells appeared cytoclasis and turned more acidophilic, and nuclei disappeared in RSA.

结果：在绒毛组织中，IL-8蛋白定位于绒毛上皮细胞的细胞质内，且病例组的表达明显高于对照组；在蜕膜组织中；病例组蜕膜细胞的胞质内可见IL-8蛋白表达，且高于对照组；H-E染色可见病例组绒毛组织的滋养层变薄，细胞变性甚至坏死、嗜酸性增强，绒毛中轴纤维化程度增强；蜕膜组织中蜕膜细胞失去细胞间连接，部分蜕膜细胞解体、核消失。

Objective To study the relationship between IL-1,MMP-13and pathogenesis of knee osˉteoarthrosis.Methods IL-1and MMP-13were measured concurrently in synovial fluid samples from23patients with mild OA,28patients with severe OA and6patients with disciform meniscus.The determinations of positive rate of cells in genual synovium with IL-1and MMP-13were carried out using immunohistochemical techonology.

目的 探讨白细胞介素-1（IL-1）、基质金属蛋白酶-13（MMP-13）在膝关节骨性关节炎发病中的作用方法提取23例OA病变轻微患者、28例OA病变严重患者、6例对照者的滑膜组织及关节液，采用免疫组织化学方法检测膝关节滑膜组织中IL-1、MMP-13的阳性细胞率及通过夹心ELISA法测定膝关节滑液中IL-1、MMP-13含量。

Specific gene expression of the pro-inflammatory cytokine IL-1β and the type II IL-1βreceptor (IL-1RII, 'decoy receptor') was studied in skin of rainbow trout Oncorhynchus mykiss (Walbaum, 1792) fry during infection with the ectoparasitic monogenean Gyrodactylus derjaini Mikailo, 1975. Cytokine expression was studied in both primary and secondary infections using a semi-quantitatie RT–PCR technique.

用半定量RT-PCR的方法，研究初次感染和二次感染体外寄生的单殖吸虫---三代虫后，虹鳟鱼苗的皮肤中促炎症细胞因子IL-1β及IL-1βII型受体（IL-1RII）的特异性基因表达。

Specific gene expression of the pro-inflammatory cytokine IL-1β and the type II IL-1βreceptor (IL-1RII, 'decoy receptor') was studied in skin of rainbow trout Oncorhynchus mykiss (Walbaum, 1792) fry during infection with the ectoparasitic monogenean Gyrodactylus derjavini Mikailov, 1975. Cytokine expression was studied in both primary and secondary infections using a semi-quantitative RT–PCR technique.

用半定量RT-PCR的方法，研究初次感染和二次感染体外寄生的单殖吸虫---三代虫后，虹鳟鱼苗的皮肤中促炎症细胞因子IL-1β及IL-1βII型受体（IL-1RII）的特异性基因表达。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

In fact, any factor which interfere the formation of the hexameric IL-6 receptor complex might inhibit or antagonize the effect of IL-6. These factors include the IL-6 mutant, sIL-6Rα mutant and soluble gp130, as well as their antibodies.

事实上，任何能干扰IL-6信号转导中异六聚体复合物形成的因素都可能抑制或拮抗IL-6的作用，其中包括IL-6的突变体分子、sIL-6Rα的突变体分子和可溶性gp130分子以及它们的抗体。

Methods: 5% propranolol emulsion was applied externally on the back of a guinea pig\' s ear to produce the psoriasis-like dermatitis model to observe the effects of Baibi ointment on the histopathological changes of the model.Radioimmunoassay was used to observe the levels of cytokines like IL-2、IL—6 and IL-8, and the effects of the ointment to the cytokines. MTT method was used to study the effects of the extracts of the Baibi Formula and the extracts of its main components Huangjing , Kushen , Dahuang ,Huangbai, to the multiplication of HaCaT cells—one of the Malpighian cell line with and without stimulation of TNF-α.

实验采用5%心得安乳剂建立豚鼠银屑病样皮炎模型，观察白疙软膏对豚鼠银屑病样皮炎模型组织病理改变的影响；采用放射免疫法检测豚鼠银屑病样皮炎模型皮损中细胞因子IL-2、IL-6、IL-8的水平，观察白疕软膏对豚鼠银屑病样皮炎模型皮损中细胞因子的影响；采用MTT法研究了中药白疕方提取液及白疕方主要组成药物大黄、黄柏、黄精、苦参提取液对角质形成细胞系HaCaT细胞增殖的影响及对TNF-α刺激后的角质形成细胞系HaCaT细胞增殖的影响。

RESULTS Plasma levels of IL-8, IL-10, MMP-9 were higher at 1 h, 4 h and 6 h aortic dclamping off in continuous ventilation and the nonventilation group, and IL-8 level were significantly higher in nonventilation group compared with ventilation group, IL-10 levels were significantly higher in the ventilation group than nonventilation group after 1 h and 4 h, 6 h, TIMP-1 levels were significantly higher in the ventilation group than that in nonventilation group after 1 h and 4 h.

TIMP-1的血浆水平在术后持续升高，在术后1 h和4 h持续通气组较非通气组明显增高。血浆中TXB2水平在主动脉开放后1 h、4 h和6 h明显高于术前水平，持续通气组较非通气组水平明显降低。支气管肺泡灌洗液中IL-8、IL-10、MMP-9和TXB2 水平在主动脉开放后4 h较术前明显升高。

It is also found that the level of IL-18BPa has a negative correlation with PASI score. This finding indicates that IL-18BPa as an inhibitor decreases in the plasma of psoriatic patients.

我们既往的研究发现银屑病血清中存在细胞因子异常，本文的研究发现银屑病患者血浆中IL-18BPa的浓度比正常人减少，进行期血浆中的浓度最低，退行期血浆中的浓度与正常人相近，与银屑病PASI评分呈负相关性，说明在银屑病外周血中存在抑制因子IL-18BPa的下降，IL-18/IL-18BP负反馈环路的异常，使Th1反应增强，可能在银屑病的发病机制中起到重要作用。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。