查询词典 Gene

The hypermethylation of 5 CpG in promoter region serves as a mechanism of the inactivation of RASSF1A gene. This mechanism has been widely confirmed in multiple tumorgenesis including prostate carcinoma cell line DU145. Object Our study is to disclose the epigenic mechanism of the carcinogenesis of prostate cancer. Including: 1. We use demethylation agents in combination with chemotherapeutic drugs, to disclose whether demethylation agents can enhance the anticancer effect of chemotherapeutic drugs. 2. to study whether demethylation drugs can affect the methylation level of RASSF1A gene in.

目的 本研究旨在探讨前列腺癌的表遗传学发生发展机制，包括： 1、甲基化抑制剂与多种化疗药物联合应用，探讨二者间的协同作用，增强化疗药物疗效； 2、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因甲基化水平的影响； 3、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因及蛋白表达的影响，以期为进一步深入探索通过改变抑癌基因的甲基化而为前列腺癌发生机制和基因治疗提供有意义的数据和理论依据。

Ms is a dominant sterile gene and Rf is a dominant epistatic gene.

萍乡显性核不育水稻不育株的育性由两对显性核基因Ms〓和Rf〓互作控制。

In S. erythraea, pZW could express reporter genes thiostrepton resistance gene and enhanced green fluorescin gene. And it is more suitable to express exogenous genes in S. erythraea stably.

在糖多孢红霉菌中，pZW可以表达硫链丝菌肽抗性基因和绿色荧光蛋白基因，是更适合在糖多孢红霉菌中稳定表达外源基因的整合型表达载体。

As most Streptomyces promoters are invalid in S. erythraea, the promoter of erythromycin-resistant gene, ermE, and Streptomyces chromosomic integration site, attP, and apramycin-resistant gene, apr from plasmid pSET152 are utilized to construct the expression vector pZMW.

因大多数链霉菌质粒的启动子在糖多孢红霉菌中都不能发挥作用，故利用糖多孢红霉菌染色体上红霉素抗性基因PermE启动子作表达载体启动子，并利用pSET152质粒上链霉菌染色体整合位点和氨朴霉素抗性基因，构建了表达载体pZMW。

Objective To investigate the FECH gene mutation in a Chinese family with erythropoietic protoporphyria, to explore the relationship between gene mutation and clinical manifestations so as to establish a basis for the genetic diagnosis and treatment of erythropoietic protoporphyria.

目的 对一红细胞生成性原卟啉病家系进行基因突变研究，探讨基因突变与临床表现的关系，为进一步开展基因诊断和基因治疗奠定基础。

A novel mutation in the donor splice site of intron 1 of FECH gene is first reported in a Chinese family with EPP; this mutation may lead to a deficiency of FECH gene and serve as a molecular basis of development of erythropoietic protoporphyria.

报道一FECH基因第1内含子供体剪接位点的新突变，该突变可能引发FECH基因缺陷，是EPP家系中患者发病的分子基础。

A gene sequence of the anthropogenic adiponectin spherical fragment obtained by the invention absolutely accords with a known gene sequence, and compared with the full-length adiponectin, the hydrolyzed anthropogenic adiponectin spherical fragment has stronger biological activity, fast reaction after dosage, good bioavailability and better clinic application prospect, especially when the diabetes patient receives a recanalization treatment after a myocardial infarction, the anemically myocardial damage of the diabetes patients can be eased by the exogenetic dosage.

本发明公开了一种人源性脂联素球状片段用于治疗糖尿病缺血性心脏病药物的应用，本发明所得到的脂联素球状片段的基因序列与已知的基因序列完全相符，与全长的脂联素相比，其水解以后的脂联素球状片段有着更强的生物学活性，而且给药后反应迅速，生物利用度好，有着更好的临床应用前景，特别是对糖尿病患者在发生心肌梗死后接受血管再通治疗时，通过外源性给药，以减轻糖尿病患者缺血心肌损伤。

But when they expressed alone, cry26 gene leaded inclusion body formation within or outside of the exosporium, whereas cry28 gene only induced crystal formation outside of exosporium. All of the proteins could not stably exist.

而当两个cry基因单独存在时，cry26基因表达合成的内含体位置不确定，大部分在芽胞外壁外侧形成，少数在芽胞外壁内侧形成；而cry28基因则只在芽胞外壁外侧表达合成内含体。

This course systematically describes the structure and function, transmission, expression and regulation, and evolution of genetic materials, covering basis of cytology for inheritance, molecular basis of genetic materials, Mendel's principles of inheritance, linkage and sex linkage, genemutation, variations in chromosome structure and number, quantitative genetics, inbreeding and heterosis, inheritance of bacteria and viruses, extranuclear inheritance, gene engineering, genomics, gene expression and regulation, developmental genetics, population genetics and evolution.

本课程全面系统地介绍遗传物质的结构与功能、遗传物质的传递、遗传物质的表达与调控、遗传物质的进化等，包括遗传的细胞学基础、遗传物质的分子基础、孟德尔遗传、连锁遗传和性连锁、基因突变、染色体结构变异、染色体数目变异、数量性状的遗传、近亲繁殖和杂种优势、细菌和病毒的遗传、细胞质遗传、基因工程、基因组学、基因表达的调控、遗传与发育、群体遗传与进化。

The combined analysis of the four cpDNA sequences showed similar topology to that in matK trees.2 Mitochondrial matR gene sequence analysisThe mitochondrial gene matR of 28 species representing 28 genera of Fagales, and 2 outgroups was sequenced.

3基于核核糖体185 rDNA序列的分析在185 rRNA基因最简约树的严格一致树上，壳斗目被分为两支，一支由壳斗科和南青冈科组成，另一支由核心高等金缕梅类组成，BS支持率均不高。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了