查询词典 Gene

A candidate gene could be selected because of its′biological association with diseases or being congenerous to a known gene related to the disease.

候选基因的选择可以基于与疾病间的生物学联系或是该基因与疾病某已知相关基因的同源性。

The development of research strategies and novel molecule methods in recent years have made a more careful analysis of HGT possible under natural and artificial conditions. Furthermore, horizontal transfer of catabolic gene in environment enhances biodegradation of recalcitrant organic compounds. Particularly, the delivery of catabolic gene information of conjugative plasmids to bacterial population in situ has great potential in bioenhancement.

近年发展起来的研究策略和新的分子生物学方法使人们能对自然和人工模拟状态下的水平基因转移进行更精细的分析，降解基因在环境中的水平传播促进了难降解有机物的生物降解，尤其是携带降解基因的接合质粒向原位细菌种群中的转移在生物强化中具有巨大的潜力。

The anthors choose the sensitivity of estimate gene(geological disaster,subsistent resource and fluvial corrade etc) and the important estimate gene(terrain gradient,pitch altitude and the depth of rock etc) through the geological survey and impersonal analysis of the geo-environment in Jiujiang City .

通过对九江市地质环境的调查与客观实际情况分析，选取地质灾害、已有资源和河流侵蚀作用等作为敏感因子；选取地形坡度、斜坡高度、基岩埋深等作为重要因子；采用层次分析法确定评价因子权重，采用多目标决策的敏感因子-模糊聚类综合评判法对九江市城市建设用地地质环境质量评价。

Three major clusters of numt sequences ( cyt b numt、 ATP8+ATP6 numt and ND4+ tRNA-His+ tRNA-Ser numt) were particularity amplified and sequenced from 10 species within Galliformes and A.galericalata. Comparison numts sequences with homologous mitochondrial partial genes get the different evolutionary characteristics and evolutionary speed compared to mtDNA, then examine the age of insertion of numts using the sequence divergence of numt from the mtDNA. Finally, joined Coturnix japonica、 Coturnix chinensis、 Lophura leucomelana、 Lophura swinhoii and A.albifrons mitochondrial sequences in GenBank, we study the importance function to phylogenetic research of mitochondrial genes and homologous numts.The evolutionary rate of Numts is lower than their authentic sequences of mtDNA, cyt b and ND4 gene evolve faster than homologous numts 2.5 times; ATP8+ATP6 gene evolve faster than numts 18.9 times in Galliformes. Numts show less codon position bias and transition bias under not phylogenetic pressure.

根据2004年3月GenBank登录的红原鸡核基因组草图与其线粒体基因组比对发现红原鸡核基因组中存在3段较长的线粒体假基因，利用PCR方法扩增鸡形目10种鸟类和雁形目中鸳鸯核基因组中3段numt序列：cyt b numt、ATP8及下游ATP6 numt和ND4+tRNA-His+tRNA-Ser numt，测序后分别比较线粒体基因与核同源numt序列的进化特点和进化速率，确定numt序列插入核基因组的时间，以及结合GenBank已登录的日本鹌鹑、蓝胸鹑、黑鹇、蓝鹇和1个雁形目物种——白鹅雁(A.albifrons)相应序列探讨两种同源序列对于鸟类系统进化发育重建的重要作用。

Firstly, the recombinant engineering technology related vaccine preparation was set up, including: 1. the gene knock-out based on linear DNA target molecular in vivo; 2. the selection and counterselection technology of exogenous gene knock in definite site on chromosome; 3. the Gap-repair clone technology in vivo; 4. the recombination technology of single-chain DNA and the overlapping primer; 5. Set up the new selection and counterselection technology of neo-E.

本研究首先建立与疫苗制备相关的重组工程技术包括：①基于线型DNA打靶分子的大肠杆菌体内基因剔除技术，②选择与反选择外源基因定位敲入染色体上特定位点技术，③Gap-repair体内克隆技术，④单链DNA重组技术和重叠引物介导的DNA重组技术，⑤建立&抗生素-酶切位点&选择反选择技术新技术。

In order to investigate the role of ICAM-1 and VCAM-1 in the pathogenesis of glomerulonephritis, ICAM-1 and VCAM-1 expression were evaluated from both protein and gene level by in vivo and in vitro study, We have conducted (1) immunocytochemical analysis and in situ hybridization to examine the alteration in expression of ICAM-1 and it's relationship with interstitial infiltrating cells and TNFα; A total of 64 renal biopsies were classified in three groups according to the degree of cellular proliferation and infiltration in glomerulus;(2) indirect immunofluoresence and immunoblotting. methods to detect the VCAM-1 level both in renal tissue and in serum from the patients of lupus nephritis (17cases) and crescentic nephritis (4 cases);(3) Cell ELISA and northern blot technique to study the effects of TNFα and IL-1β on ICAM-1 and VCAM-1 surface expression and gene expression by cultured human mesangial cells .

为了探讨ICAM-1和VCAM-1在肾小球疾病中的作用，本文从蛋白质和基因两个水平，整体（研究ICAM-1时根据肾小球内细胞增生和浸润程度，将64例病人分为A.B.C三组）和细胞培养两个方面，做了如下工作，（1）利用免疫细胞化学和原位杂交技术观察了ICAM-1在64例肾小球疾病患者中的表达及其与间质浸润细胞、TNFα之间的关系；（2）利用间接免疫荧光和膜免疫印迹方法检测了VCAM-1在17例狼疮肾炎和4例新月体肾炎病人肾组织及血清中的表达；（3）利用细胞ELISA和Northern杂交技术研究了IL-1β或TNFα对体外培养的人肾小球系膜细胞ICAM-1和／或VCAM-1表面表达及mRNA表达的调节作用。

Crocin can induce the significant alteration of gene expression profile of T24 cell. It is suggested that the widly konwn anti-tumor effects of crocin are medicated at least in part by regulating the cell cycle controlling gene expression.

藏花素可以诱导T24细胞基因表达谱广泛的改变，并可能通过调控细胞周期相关基因的表达来抑制T24细胞的增殖。

We named it as CS-ACSG gene (The gynoecious-specific ACC synthase gene in Cucumis sativus L.).

此结果说明CS-ACSG基因与黄瓜雌性表达的关系非常复杂。

Taken together, these results indicate that cosuppression of the tobacco chs gene can occur using the equivalent Petunia gene, and demonstrate a linkage between the expression level of chs mRNA, cyanidin content, and flower color in transgenic tobacco plants.

综合而言，本研究提供了广泛的实验证据，说明菸草chs基因的共同抑制作用是可以透过别种植物如矮牵牛的相似基因而发挥作用，导致转殖菸草产生白色花朶；并清楚显示chs mRNA表现量、花青素含量及转殖菸草花朶颜色的关联性。

To search the genetic heterogeneity of ADPKD and to compare the clinical presentation between ADPKD type 1 and 2 in Shanghai Han population, develop a method of gene diagnosis by linkage analysis with microsatellite DNA tightly linked to PKD1 and PKD2 and make gene diagnosis of mutation carriers before cystogenesis, detect single nucleotide polymorphism of PKD2 and its frequence in Han population.

根据知情同意的原则，选取80名无亲缘关系的上海市汉族健康志愿者进行与PKD1和PKD2连锁的微卫星DNA多态性的研究，选取43个常染色体显性多囊肾病家系进行遗传异质性、表型差异研究及基因诊断。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了