查询词典 Gene

To continue the previous work from our laboratory, the purpose of this study is to investigate IGFBP-5 gene expression by BP and ripen areca nut extract in NHOKs . The results in this study suggest that BP and rANE exhibited inhibition effects on IGFBP-5 gene expression both on transcription and translation levels in NHOKs .

本研究发现， BP 及老槟榔萃取物对於正常口腔角质细胞中 IGFBP-5基因之表现均有抑制之效果，且此抑制效果不但发生於基因转录阶段，甚至还持续到转译阶段；类似的结果也在 SCC25细胞中观察到。

By using array technology, gene expression can be studied to improve our understanding of the complexity of the plant transcriptome and interactions between genes and gene products.

通过使用阵列技术，基因的表达进行研究，以提高我们对核电厂的转录组和基因与基因之间的相互作用的复杂性的认识产品。

Methods Sequence specific primers-polymerase chain reaction was used for the detection of genotypes and alleles of rs3850641 A/G loci in OX40L gene in 187 PACS cases (≤55 years) and 138 controls. Diseased vessel numbers and stenostic severity integral by coronary arteriogram and serum levels of sOX40L, C-reactive protein and vascular cell adhesion molecule-1 (VCAM-1) by enzyme-linked immunosorbent assay and nephelometry were measured. The relationship between OX4OL gene variants and PACS risk, SSI as well as plasma levels of three cytokines were analysed.

采用聚合酶链反应－序列特异性扩增技术检测187例年龄≤55岁、早发急性冠状动脉综合征患者和138例冠状动脉造影正常者rs3850641位点A/G变异的基因型、等位基因及其分布频率；采用冠状动脉造影测量病变血管支数和狭窄程度积分；应用ELISA法测试血浆sOX40L、血管细胞黏附分子(VCAM-1)；应用散射比浊法测试血浆C反应蛋白水平；分析OX40L基因变异与ACS风险、冠状动脉病变程度和血浆3个细胞因子之间的关系。

BACKGROUND: Neonatal-onset multi-system inflammatory disease, a rare autosomal dominantly inherited disease, belongs to a growing spectrum of autoinflammatory diseases, is characterized by urticarial rash, arthropathy, and chronic aseptic meningitis, and is associated with mutations in the cold-induced autoinflammatory gene, CIAS1, the gene that encodes the protein, cryopyrin.

背景：新生儿开始发病的多系统炎性病是一种罕见的常染色体显性遗传性疾病，属于自身炎性疾病逐渐庞大的范畴，表现特征为荨麻疹、关节病和慢性无菌性脑膜炎，它合并有冷刺激诱发的自身炎性基因 CIASI 的突变，该基因是编码蛋白质和 cryopyrin 。

The female salivary gland proteins were influenced by JH Ⅲ. Treatment on d2 after feeding, 10μg dose increased SG protein level and restrained 136kD protein gene expression. Treatment on d0 after engorgement, 10μg, 50μg and 100μg doses significantly increased the d2 SG protein and 100μg dose made 35kD protein gene expression, 200μg treatment made the 136kD and 192kD proteins absent. This is the first found that JHs regulate arthropoda SG activity.

保幼激素对雌蜱唾液腺蛋白及成分有影响，吸血后2天处理，10 μg剂量使唾液腺蛋白含量明显增加，抑制136kD蛋白的基因表达；饱血当天处理，10μg、50μg和100μg显著提高饱血后2天唾液腺蛋白含量，100μg使35kD蛋白表达，200μg使136kD和192kD的蛋白缺矢；饱血当天处理，1μg和10μg剂量均能显著提高饱血后4天雌蜱唾液腺蛋白含量，高剂量（100μg）抑制136kD蛋白的表达，该结果首次报道了保幼激素对节肢动物唾液腺的调控作用。

In whole test process, to compared with control group, hepatic hepcidin gene expression of test group on different phases had obviously differences with retinoic acid was administered. On early phase of test group , relative gene expression contents of hepcidin were gradually fall and the lowest level was on 8th、9th、10th day, then the hepcidin level gradually was ascendent. The curve was like a cavate parabola.

在实验周期内，模型组与对照组比较，肝脏铁调素基因表达在维甲酸灌胃的不同时间，存在明显差异：早期5、6、7天铁调素基因相对表达量逐渐下降，在第8、9、10天达到较低值，随后有回升，呈现凹陷的抛物线变化趋势；而对照组基本处于水平的轻微波动变化。

The results show that all the hmgr genes from pigs, cattle and chickens are astable enzyme proteins with the same gene sequence characteristics and encoding protein and physical and chemical properties; all the amino acid sequences have a high degree of homology, containing two conservative HMG-CoA binding motifs and two NADPH binding motifs; all the amino acid sequences, containing signal peptide, are secreted proteins; they are all hydrophobic transmembrane proteins with five transmembrane domains; random coil and α-helix are the main structural elements in the HMGR polypeptide chain; all the predictions of three-dimensional structure are V- shaped; there are more closer evolution relationship between the HMGR gene from pigs and cattle.

结果表明：猪、牛和鸡HMGR基因序列特点及编码蛋白质理化性质基本相同，均属不稳定类酶蛋白；保守结构域氨基酸序列具有高度的同源性，均含有保守的2个β-羟基-β-甲基戊二酸单酰辅酶A结合基序和2个还原性烟酰胺腺嘌呤二核苷酸结合基序；均有信号肽，属分泌型蛋白质；属于跨膜的疏水性蛋白，均有5个跨膜结构域；无规则卷曲和α-螺旋是HMGR多肽链中的主要结构元件；三维结构预测都呈"V"字形；猪和牛HMGR基因的进化关系最近。

The rps3 gene of ribosomal protein gene for the CWB-GZh shared highest homology (98.1% and 100%) with phytoplasma strains in Aster yellows (16SrI-B group) and Periwinkle yellows (16SrI-B group).

CWB-GZh株系核糖体蛋白基因rps3基因编码的氨基酸序列同源率与16S rI–B亚组的AY和PY最高达98.1%和100%。

But it is obviously under 97.0% with other groups. With further comparing the rps3 gene of ribosomal protein gene for the CWB-YN strain,the results show that these strains shared highest homology (98.1% and 100%)with Aster yellows and Periwinkle yellows.

进一步比较CWB-YN株系核糖体蛋白基因rps3基因编码的氨基酸序列同源性，结果与16S rI–B亚组的翠菊黄化病植原体(Aster yellows，AY)和长春花黄化病植原体(Periwinkle yellows，PY)的同源性最高，分别达98.1%和100%。

A novel gene CCR (Cell-Cycle Related) was cloned from Atriplex hortensis. Northern blot analysis showed that the CCR gene specifically expressed during G1 and early S phase of the cell cycle, but suppressed by ABA treatment.

从山菠菜和拟南芥中克隆了一个新的未知功能的植物基因，编码DNA结合蛋白，其在细胞周期的G1和S期特异表达，受ABA抑制，命名为CCR（Cell-CycleRelated）。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。