查询词典 Gene

Opportunistically expressed (usually at the basal levels of transcription), but still permit the continued expression of genes that are regulated by strong promoters/enhancers (such as housing-keeping gene), the expresison of these genes might play a key role in the embryonic development; 5 The sum of these two opposing processes-activation and repression-would dictate the final pattern of gene expression that manifests itself as a dramatic reprogramming of gene expression during the maternal-to-zygotic transition and support further embryonic development.

这些基因的表达对于胚胎的后继发育可能是至关重要的；5）通过胚胎基因表达的激活与抑制：这两个作用相反的机制依不同时间顺序协同作用于胚胎基因，从而在指导胚胎发育的控制权由母源性表达产物移交到胚胎特异的基因表达产物的过程中&再程序化&胚胎基因的表达，形成特定的表达模式，以支持胚胎的后继发育。

P16 gene is composed of two intervening sequences and three exons , and encodes p16 protein , which is the inhibiter of CDK4 and CDK6 . They can together prevent phosphorylation deactivation of pRB , and make the cell cycle blocked in G1 stage. P16 gene promoter region has a great of CpG islands , which can be methylated when some adverse factor appears , and so the genetic transcription of p16 can be inhibited , which leads to gene silencing, cell paraplasm, and tumor generate.

抑癌基因p16编码蛋白P16 ，是细胞周期蛋白CDK4和CDK6抑制剂，它阻止pRB磷酸化失活，使细胞周期阻滞于G1期。P16基因启动子区域富含CpG岛，当受到各种有害因素影响时，容易发生甲基化，从而抑制P16基因转录，导致基因沉默，细胞异常增生，导致肿瘤的发生[5]。

Comparing the nucleotide sequences of 16S rRNA gene and ribosomal protein gene, we could find that these two strains have the highest homology of 99.4% and 99.8%, respectively. The nucleotide sequences of 16S rRNA gene for the CWB-YN strain shared higher homology (98.5%,98.9% and 98.0%) with phytoplasma strains in Tomato big bug 16SrI-A group, Western aster yellow (16SrI-B group and Clover phyllody (16SrI-C group). But it is obviously under 97.0% with other phytoplasma groups. The CWB-GZh strain shared higher homology (98.7%,99.1% and 98.3%) with phytoplasma strains in Tomato big bug(16SrI-A group ),Western aster yellow (16SrI-B group) and Clover phyllody (16SrI-C group).

苦楝丛枝病植原体云南株系与其它组16S rRNA基因序列的同源率进行比较，结果与16SrI-A组中的番茄巨芽病植原体(Tomato big bug，BB)、16SrI-B组中的西方翠菊黄化病植原体(Western aster yellow，SAY)和16SrI-C组中的三叶草变病植原体(Clover phyllody，CPh)同源率达最高，分别为98.5%、98.9%和98.0%，而与其它组的植原体16S rRNA基因序列的同源率均低于95%；苦楝丛枝病植原体贵州株系与16Sr I-A组的番茄巨芽病植原体(Tomato big bug，BB)、16Sr I-B组的西方翠菊黄化病植原体(Western aster yellow， SAY)和16SrI-C组中的三叶草变叶病植原体(Clover phyllody，CPh)的同源率达最高，分别为98.7%、99.1%和98.3%。

Nodosus pilin and the killed D. nodosus vaccines. It also means that the IL-2 in the fused Pilin-IL2 construct may also have a potential role in stimulating vaccine antigen .Key words: D. nodosus Recombinant Pilin gene Recombinant Ovine IL-2 gene Fused Pilin-IL2 gene

用Pilin-IL-2融合基因工程疫苗免疫健康家兔的初步免疫试验结果表明，2l天后产生较高的凝集效价，达到〓，甚至稍高于加佐剂的前三种疫苗，证明绵羊IL-2基因与Pilin基因融合后，可起到一定的免疫佐剂作用。

GAP gene was found to be a good internal control for the first time for studying gene expression in H. polymorpha. It was shown by Northern hybridization that H-OLE1 gene was expressed in H.

为研究H-OLE1基因的转录及其调节规律，通过一系列实验，首次找到了可在研究多形汉逊氏酵母基因表达时用作内标的GAP基因。

Because Cx43 gene is the first a connexin gene to be associated with non-syndromic deafness, we have sequenced the coding region of Cx43 gene from 190 Taiwanese patients with prelingual deafness and 130 unrelated normal individuals.

Cx43基因是connexin α家族中第一个被发现与非症候群听障有关的基因，我们收集台湾地区190位语言学习前期听障患者，及130位听力正常人血液DNA做Cx43基因的分析。

We studied the mutation of PDS gene in children diagnosed to have prelingual non-syndromic hearing loss with concomitant bilateral large vestibular aqueduct and Mondini's dysplasia. We tried to find the correlation between non-syndromic hearing loss in local patients and PDS gene, and to establish the basic data of PDS gene mutations in Taiwan.

本篇研究之目的，乃对於患有非症候群学语前听障并合并双侧大前庭导水管及Mondini氏发育异常（Mondini's dysplasia）的儿童，作基因的分析，尝试找出本土非症候群听障与PDS基因的关连性，以建立台湾地区PDS基因突变的基本资料。

Objective: Presymptomatic gene diagnosis of autosomal dominant polycystic kidney disease families by PCR Methods: Genomic DNA were extracted Highly polymorphic microsatellite markers(SM7, AG2 5, KG8, CW2) linked to the PKD1were amplified using PCR Ten ADPKD families (104 members,including 28 affected) were analysed Results: Nine children were diagnosed with presymptomatic gene diagnosis ,although all children presented a negative ultrasonic diagnosis Conclusion: The presymptomatic gene diagnosis ...

目的：应用PCR方法对常染色体显性遗传性多囊肾病家系进行症前基因诊断。方法：用PCR扩增与PKD1位点连锁的的高度多态性的微小卫星体DNA（SM7，AC2.5，KG8，CW2）为遗传标记，对10个ADPKD家系的104个成员（包括28个患者）找出染色体上与疾病连锁的单体型，进行连锁分析。结果：对9个无临床症状，且B超检查呈阴性结果的儿童做出了症前基因诊断。结论：能够应用PCR方法对ADP－KD家系成员快速、准确地做出基因诊断

The main methods used, or under investigation, for production of rumen gene engineering bacteria are:gene deletion technique, gene recombination technique and the application of promotor.

正在应用的或处于研究阶段的构建瘤胃基因工程菌的方式主要有基因缺失技术、基因复制性重组技术和启动子的应用技术。

Three genes specified expressed in hybrids and one gene over-expressed in hybrid were found. By cloning, sequencing and BLAST analysis, one specific expression cDNA band was cytosolic isocitrate dehydrogenase gene, the other two were new genes which function were unknown, and the over-expressed cDNA band was proteosome subunit p112 gene.

发现了 3 个杂种鸡特异表达的基因和 1 个杂种鸡表达增强的基因，进一步克隆、测序和比对分析初步表明：杂种特异表达的 cDNA 片断分别为鸡细胞质异柠檬酸脱氢酶基因和 2 个未知功能的新基因；杂种表达增强的 cDNA 片断为鸡蛋白酶体亚基 p112 基因。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。