查询词典 FAS

Methods: Immunohistochemical assay was used to detect the expression of COX-2 and Fas in 38 osteosarcoma tissues (38 cases) and 20 osteochondroma tissues (20 cases).

应用免疫组化SP法检测38例骨肉瘤组织、20例骨软骨瘤组织中COX-2和Fas的表达。

Objective To investigate the relationship between the differentiation of osteogenic tumor cells and different expression ways of c-myc and fas protein.

目的 针对c-myc、Fas蛋白在肿瘤细胞中不同表达方式，探索其与成骨性肿瘤细胞分化的相关性。

When Fas and c-myc protein were coexpressed in cytoplasm, a strong positive sign appeared in highly differentiated osteosarcoma, fibrous dysplasia of bone and osteoplast of bone callus, a weak sign was found in low-differentiated tumour cells and fibroblasts.

Fas和c-myc蛋白胞浆内阳性，在骨肉瘤的高分化细胞(骨母细胞型和软骨细胞型瘤细胞)和骨化性纤维瘤、骨纤维结构不良、骨痂组织中骨母细胞呈强表达；而在低分化瘤细胞和纤维母细胞则呈弱表达。

A large number of the positive Fas-cells, in spleen, distributed in red pulp and the surrounding area of periarterial lymphatic sheath scatteredly or in clusters.

大量Fas表达阳性细胞分布于红髓和动脉周围淋巴鞘的周围；阳性细胞簇团状或散在分布。

The liver specimens were immunohistostained by SP method (1)Fas antigen and FasLs specific positive signals were found mainly on the surface or/ and in the cytoplasm of the hepatocytes, these positive hepatocytes were scattered nearby periportal region and hepatic lobule with piecemeal necrosis, the infiltrating lymphocytes were mainly FasL-positive cells.

1Fas、FasL在肝组织肝细胞膜及胞浆均有不同程度表达，其表达阳性细胞主要位于汇管区小叶内及周边碎屑状坏死区，呈弥漫分布，在其周围浸润的淋巴细胞上多为FasL阳性细胞，亦可见到Fas阳性细胞。

Methods MTT Chromatography is adopted to test effects of 5-FU of different concentration and at different time of reaction over growth of Lovo cells; photomechanical method used to observe configuration and characteristics of apoptosis cells; FCM employed to test the percentage of apoptosis cells; electrophoresis and immunized grouping SP applied to test antigen Ki-67 of Lovo cells proliferation and expression of P53 and Fas genetic proteins in relation to apoptosis.

采用四甲基偶氮唑盐显色法，检测不同浓度5－FU作用不同时间对Lovo细胞生长所产生的不同影响；光镜观察凋亡细胞的形态特点；流式细胞术检测凋亡细胞百分率；琼脂凝胶电泳、免疫组化SP法检测 Lovo细胞增殖核抗原Ki－67及凋亡相关基因蛋白p53、Fas表达水平。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Fas and Bax proteins are the important parameters reflecting the radiosensitivity and predicting the radiotherapeutic effec of squamous cell carcinoma of esophagus.

Fas和Bax蛋白是反映中晚期食管鳞癌肿瘤细胞的放射敏感性和判断术前放疗效果的重要指标。

The levels of serum SAPO 1/Fas in acute leukemia patients are significantly related to the chemotherapeutic efficiency.

APO- 1 /Fas与其配体是已认识到的一对诱导细胞凋亡的膜蛋白因子，它们之间构成一条独特的细

The positive Fas-cells, in spleen, distributed in red pulp scatteredly or in clusters.

Fas表达阳性细胞分布于红髓；阳性细胞簇团状或散在分布。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。