查询词典 ER

Exogenous E2 alone has no effect on cell viability and apoptosis of H9C2 cells, but it can decrease the sensitivity of H9C2 cells to H_2O_2,hence,protect cells against apoptosis caused by oxidative stress.2Exogenous E_2 has downregulation effect on TβRⅠand TβRⅡof H9c2 cells,blocking ER may delete this effect of estradiol.H9c2 cells express ERβonly,suggests that E_2 may exert modulating effect on TGF-βpathway through ERβ.

外源性E2本身并不能影响H9c2细胞凋亡，但能够降低H9c2细胞对H_2O_2的敏感性，保护细胞抵抗氧化应激引起的凋亡。2外源性E2对H9c2细胞的TβRⅠ以及TβRⅡ具有下调作用，阻断ER可消除E2对TβRⅠ和TβRⅡ的下调作用；E2可进一步通过TGF-β通路降低受体后磷酸化smad2/3的水平；H9c2细胞仅表达ERβ，提示E2可能是通过ERβ发挥其对TGF-β通路的调控作用。

At Er~(3+) doping concentration range 0.1-1.5 mol%, Er~(3+) first arrived at ~4F_(7/2) energy level by excited state absorption, then rapidly relaxed to ~2H_(11/2) and ~4S_(3/2) energy levels, the population of which increased, the remarkable upconversion green emission was obtained when Er~(3+) directly went back to ground state by radiative transition.

Er~(3+)浓度在0.1-1.5 mol％时，Er~(3+)通过激发态吸收跃迁到~4F_(7／2)能级，后迅速无辐射弛豫到~2H_(11／2)、~4S_(3／2)能级，~2H_(11／2)和~4S_(3／2)能级上Er~(3+)的布居数增多，Er~(3+)直接辐射跃迁回基态，上转换发射以绿光为主。

ERα is the major subtype of estrogen receptor in vaginal tissue of rats. ERα and ERβ expressions are down-regulated in the vaginal tissues after ovariectomy. Our findings show that estradiol valerate can up-regulate the expression of ERα but ERβ.

ERα是大鼠阴道优势表达的雌激素受体亚型；去势后阴道ER亚型表达下调，以ERβ明显；戊酸雌二醇可明显上调去势大鼠阴道ERα的表达，但不上调ERβ的表达。

Nm23, VEGF and ER can be used as markers in the prognostication of breast cancer. Patients with nm23, ER positive and VEGF negative have better postoperative prognosis. Expression of ER can be used as an early marker, Postmenopausal breast cancer patient should apply more active endocrinotherapy.

我们认为，乳腺癌的发生与癌组织中的 nln23、pZI VEGF和 ER过度表达有密切相关，nln23阳性、VEGF阴性和 ER 阳性的乳腺癌术后预后较好，癌组织中的m23、VE GF和ER表达可以作为判断乳腺癌预后的指标；ER的表达可以作为乳腺癌的早期标记物；绝经后乳腺癌病人应采取更积极的内分泌治疗。

Results: 1 Intense ERα immunoreactivity localized in the hypertrophic and maturative layer, and some immunoreactivity was found in osteoblasts of mandible and temporal bone, while no immunoreactivity was found in the disc and synovium. 2 The expression of ERα in male rats TMJ cartilage was higher than that in female ones. 3 In the condyle cartilage of male rats, the density of ERα positive cells decreased with age, which kept stable after 16 weeks of age. 4 In the condyle cartilage of male rats, the density of ERα positive cells was stable from birth to 8 weeks, but decreased from 16 weeks to 12 months, while the density in 18-month group recovered to the level of 8 weeks. Conclusion: TMJ is one of target organs of estrogen, and ERα plays an important role in the effect of estrogen on TMJ.

结果：1TMJ中ERα主要在髁突软骨的肥大层和过渡层表达，下颌骨和颞骨的骨细胞也有少量表达，而关节盘、滑膜中几乎无表达；2雄性SD大鼠髁突软骨中ERα的表达明显强于同龄的雌性大鼠；3在雄性大鼠TMJ髁突软骨中阳性细胞密度随年龄增长逐渐降低，16周以后逐渐维持在相对稳定的水平；4雌性大鼠从出生后到8周龄阳性细胞密度基本稳定，在16周龄至12月龄年龄组阳性细胞密度显著降低，而在18月龄后又恢复到8周龄以前的水平。

All results above indicated that:The expression of ERβand p-ERβin mouse ovary at oestrous cycle and in early gestational period changed regularly, it showed that ERβand p-ERβhad important effects to ovaries development, ovarian follicles groth, oocyte maturation and form corepus luteum in female mouse ovary during oestrous cycle and in early gestational period.

以上结果表明：ERβ及其磷酸化形式——p-ERβ在小鼠发情周期以及妊娠早期卵巢中表达有规律性的变化，揭示ERβ与p-ERβ在雌性小鼠发情周期及妊娠早期，对卵巢发育、卵泡生长、卵母细胞成熟和黄体形成有重要的作用。

The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P＜0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P＜0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝脏ERα及其mRNA基因的表达分布于肝细胞及肝脏非实质细胞，特别以肝脏中央静脉和门脉周围为主；卵巢切除减少ERα及其mRNA基因的表达（P＜0.05）；雌二醇治疗在肝纤维化和卵巢切除大鼠均提高肝脏ER及其mRNA基因的表达（P＜0.05），其增加程度与肝脏组织学损伤、纤维化指标的降低程度以及肝脏胶原沉积减少相平行。

Conclusions1、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

结论1、E_2可增加Jurkat细胞的凋亡，并增加Fas、FasL的蛋白表达，且其作用与E_2的剂量和处理时间呈正相关。2、Jurkat细胞上存在ERα、ERβ的表达，且E_2可上调这两种受体的表达，E_2剂量越大，ER表达量越高。3、E_2可能通过ERβ发挥其促进Jurkat细胞凋亡的作用。4、E_2能增加Jurkat细胞中NF-κB的转录活性，Jurkat细胞中NF-κB活性增加有促进凋亡的作用。

PL spectra indicate that the emission bands at 515 and 542 nm correspond to the 2H(subscript 11/2)→4I(subscript 15/2) and 4S(subscript 3/2)→4I(subscript 15/2) transitions of Er(superscript 3+), respectively. In the samples, the cerium dopant exists as Ce(superscript 3+) and Ce(superscript 4+). Ce(superscript 3+) sensitizes Er(superscript 3+) and enhances the luminescence intensity of the doped nanorods remarkably and energy transfer from Ce(superscript 3+)→Er(superscript 3+) was observed.

对发光机理的初步研究表明：发光分别对应于Er(上标 3+)的2H(下标 11/2)→4I(下标 15/2)，4S(下标 3/2)→4I(下标 15/2)跃迁，铈离子以Ce(上标 3+)和Ce(上标 4+)两种形式存在于体系中，Ce(上标 3+)对Er(上标 3+)起敏化作用，可以显著增强β-BBO：Er(上标 3+)/Ce(上标 3+)/Ce(上标 4+)纳米棒的发光强度，存在Ce(上标 3+)→Er(上标 3+)的能量传递过程。

Er concentration.2. With the analysis of the optical parameters calculated by Judd-Ofelt theory and the lifetime of ~4I_(13/2) of Er gotten in experiment, we investigated Y dopings dispertion effect and influence to the environment of Er .3. In the research of Er/Yb/Al co-doped laser glass, we fixed the Er:Yb at 1:6 and varied the Al concentration.

我们利用Judd-Ofelt理论，计算得到了Er/Y共掺玻璃的Judd-Ofelt强度系数、光谱质量因子、自发辐射弛豫率和能级寿命等光谱参数，并且给出了不同Y掺杂浓度下Er~(3 )离子的荧光量子效率；结合Er~(3 )离子~4I_(13/2)能级的荧光寿命，深入探讨了掺Y对高浓度Er~(3 )离子在硼硅酸盐玻璃中分布的弥散作用和对配位场环境的影响。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。