查询词典 DN

Results The quantity and volume of the blood platelet in diabetic nephropathy may change evidently and take effect in DN.

DN时血小板的数量、体积均发生明显改变，在DN的发生、发展中起一定作用。

With extension of keeping in storage diastase number of honey in six samples show different varying rule: the DN of the superior samples descend distinctly, but that of the inferior change not too obviously.

且随着放置时间变长，几种蜂蜜呈现出不同的变化规律：优质品A、B、F的DN值下降明显，而劣质品C、D的DN值变化不大。

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的：为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响，我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC，在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间，观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)／基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化，同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响，并进一步探讨金雀异黄素发挥作用的可能机制；为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

Based on the aim to make up the impercipience of NO in DN, the role of NO in DN was studied in some depth here through three different ways, i.e. in vitro, in vivo, and the Mendels genetic means.

为了有助于弥补人们当前对NO与DN认识的不足，本课题拟从体外、体内实验和群体遗传学三个角度对NO在DN中的作用机理进行深入研究。

Methods The thickness of retinal capillary basement membrane and glomerular basement membrane and their anionic sites were quantitatively analyzed by electron microscopy and immunohistochemical methods.Results RBM and GBM became gradually thickened with the development of diabetes. The thickened basement membrane was accompanied with decrease of anionic sites in number.Conclusion DR and DN share partly the pathological process, and there are also some incoordinate phenomena in the microvascular lesion.

我们采用普通电镜和免疫组化电镜等方法对糖尿病动物模型进行了系统观察，着重对比分析视网膜和肾小球微血管病变，试图寻找DR和DN的相关性，以期阐明其发生、发展的规律，为临床探索或延缓糖尿病患者并发DR或DN的手段提供理论依据。

The time delay (T1) that NAND gate 403 takes to generate a falling edge in VIN plus the time delay (T2) that a falling edge in VIN takes to propagate through pulse width generator 404 to VOUT plus the time delay (T3) for flip-flops 401 and 402 to generate falling edges in the UP and DN signals after a falling edge in VOUT equal the minimum pulse width of the UP and DN signals (T1+T2+T3=MPW).

NAND门403在VIN中生成下降沿的时间延迟(T1)加上VIN中的下降沿通过脉冲宽度发生器404传递到VOUT的时间延迟(T2)再加上触发器401和402在VOUT中的下降沿后在UP和DN信号中生成下降沿的时间延迟(T3)等于UP和DN信号的最小脉冲宽度，即(T1+T2+T3=MPW)。

The corrosion fatigue crack growth and near-threshold characteristcsof high tensile steel HT60 were investigated by using the compact specimens underexposure to synthetic sea water. The da/dN vs △K_ relation in air may be conser-vetivel estimated for that in sea water. In the high △K region with high stressratio, owing to the acceleration of crack growth promoted by stress-induced dissol-ution, the crack opening stress intensity factor K_ represents only the result ofcrack surface in contact with corrosion products, so as to give an overestimation ofK_ at crack tip.

对高拉力钢HT60的腐蚀疲劳裂纹扩展特性和门槛值区域特性，采用紧凑拉伸试件在人工海水中进行了实验和研究，结果表明：在空气中的da/dN与ΔK_关系可以作为在海水中的da/dN与ΔK关系的一个偏保守的预测；在高应力比的高ΔK区域，由于应力诱起溶解促进了裂纹扩展的加速；该裂纹开口应力强度因子K_仅反映了裂纹表面同腐蚀生成物接触的结果，从而导致了K_在裂纹尖端的偏大的估计结果。

Results The pathological symptom of DN occurred in all model rats.The renal pathological structure,thickening of glomerulose basement membrane and increasing of fibronectin and collagen IV expression in renal tissue were significantly de-creased in HDC by given HDC.

结果 高血糖组大鼠均出现DN病理学特征，黄丹益肾胶囊用药组大鼠DN病理学改变明显减轻；肾小球基底膜增厚较模型组对照组小；肾组织纤维连接蛋白、肾组织Ⅳ型胶原表达明显低于模型对照组。

The average percent value of G C (49.3%) was less than that of A T (50.7%), there was a bias of the content of G, T in the third codon; The number of transition G-A and T-C were 22, 15 respectively, which were higher than that of transition A-G and C-T, the number of tranversion C-A, T-G is 2 respectively, and other tranversion patterns didnt occur; the probability of transition was higher than that of tranversion , Ts/Tv = 9.5-19, there was the highest number of transition in the third codon. The gamma parameter a of the lst,nd and 3rd codon positions were 0.00572,0.01237 and 1.05239 respectively, they showed that there was adifferent substitution rate at different codon position. Frequences of synonymous codon usage were relatively biased. The average rates of synonymous and nonsynonymous substitution were 0.0787, 0.0011 respectively, there was a significant difference between dS and dN (Z = 4.713, p.01), and the low ratio( CD = 0.0284 .3) of dN/dS ratio impled that there were selective constraints against the nonsynonymous sites in cyt-b gene, The distribution of nonsynonymous codon substitution pattern related to Grantharm distance indicated that the purified selection at 2nd codon positions was more intensive than that at 1st codon positions. The phylogenetic trees supported the view of the double origin of Chinese goose, which means that domestic Chinese goose was derived from Anser cygnoides and domestic European goose, and Yili was derived from Anser anser.

碱基含量分析可知，序列的G C含量(49.3％)＜A T含量(50.7％)，密码子第三位点的G、T含量都有较强的偏倚性；序列间G→A和T→C的转换数(22次和15次)高于A→G和C→T的转换数(10次和9次)，C→A、T→G颠换数均为2次，其余颠换模式均未发生；转换数明显高于颠换数，Ts／Tv=9.5～19，密码子第三位点的转换数最高，呈现了相当强烈的转换偏倚性；密码子第一、二和三位点的gamma分布参数α值分别为0.00572、0.01237和1.05239，表明密码子第一位点的替换速率变异最大，第二位点次之，第三位点的替换速率变异相对较小；编码同一氨基酸的同义密码子并非随机使用，表现出一定程度的使用偏倚性；同义替换速率和非同义替换速率分别为0.0787和0.0011，dS与dN值间的差异极显著(Z=4.713，p＜0.01)，而ω=0.0284，明显小于0.3，表明雁属鹅细胞色素b基因序列经历了中度净化选择作用；单步非同义替换(Sing-step nonsymonymous codon substitution，SSNCS)分布模式与Grantharm距离之间的关系说明密码子的三个位点所受的净化选择强度不同；构建的最大简约树与邻接树拓扑结构一致，支持中国家鹅的双起源学说，即除伊犁鹅外的其它中国鹅品种起源于鸿雁，伊犁鹅和欧洲的郎德鹅、莱茵鹅起源于灰雁。

Simultaneously, the exports of ionization rate and nonionzed concentration are set up as a powerful tool for studying thoroughly the freeze-out effect. dN〓/dp and dN〓/dn are neglected in the linearized equation system of the iteration methods of Newton and Gummel, due to having lower 15 orders or more than dN〓/dn and dN〓/dp, thus the computing effort is cut down with no effect on precision. A new cut-off technique is adopted to accelerate the convergence speed, about twice reduced for Newton iteration method and six times or so for Gummel iteration method. The approximate formulae of Fermi-Dirac statistics are also put forward with simpler form and higher precision. 3. A term dependent on time is added to the electron and hole current succession equations respectively. It is only this model that conservation of charge in transient analysis and alternating small-signal analysis at low temperature can be kept by. 4. The performance of SE-PISCES is explained by the simulation example of PISCES-2B, diode.

研究了低温半导体器件模拟的数值方法：对载流子浓度进行了新的归一化；编制了不考虑掺杂所引进的内建电场时的电离率计算程序；由于低温杂质电离率随偏压状态而变化，为此编制了每次求解迭代时的电离浓度计算程序，并将其插入到求解迭代程序中；同时，设置了杂质电离率和未电离杂质浓度的出口点，为更深入地研究冻析效应提供了有力工具；在Newton迭代法和Gummel迭代法的线性化方程组中忽略了dN〓/dp、dN〓/dn，是因为它们比dN〓/dn、dN〓/dp低15个数量级以上，这样减小了计算量又不影响模拟精度；对Newton迭代法和Gummel迭代法采取了新的截断技术，提高了收敛速度，Newton法迭代法和两次左右，Gummel法减少六次左右；给出了表达式更简单而精度更高的Fermi-Dirac积分近似计算公式。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。