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The simple algebraic procedure is used to form nearly orthogonal 2—D C—type and H—type bodyfitted grids for bodies of revolution, which is then used to generate 3—D C—O and H—O bodyfitted grids for fuselages.

五、用简单的代数方法生成了近于正交的旋成体子午面"C"型及"H"型贴体坐标网格,并以此为基础构造了三维任意截面机身的"C-O"型及"H-O"型贴体坐标网格。

Nine new compounds were characterized, and they were: opuntioside Ⅰ(11), 4-ethoxyl-6-hydroxymethyl-α-pyrone (14),--ester (22), 1-butoxyl--malate (24), ethyl α-L-rhamnopyranoside (26), opuntioside Ⅱ(34), kaempferol 7-O-β-D-glucopyranosyl (1→4)-β-D-glucopyranoside (46), methyl α-D-glucopyranoside-6-(methyl 4-malate)-ester (47), and opuntioside Ⅲ(48). Opuntioside Ⅰ,Ⅱ,Ⅲ and 4-ethoxyl-6-hydroxymethyl-α-pyrone belong to the skelecton of α-pyrone.

新化合物分别是:仙人掌苷Ⅰ(11),4-乙氧基-6-羟甲基-α-吡喃酮(14),琥珀酸乙酯--酯(22),L--苹果酸-1-丁酯(24),乙基α-L-吡喃鼠李糖苷(26),仙人掌苷Ⅱ(34),山奈酚7-O-β-D-吡喃葡萄糖基(1→4)-β-D-吡喃葡萄糖苷(46),α-D-吡喃葡萄糖甲苷-6-(苹果酸-4-甲酯)-酯(47),仙人掌苷Ⅲ(48),其中仙人掌苷Ⅰ、Ⅱ、Ⅲ及4-乙氧基-6-羟甲基-α-吡喃酮均为α-吡喃酮骨架类型的新化合物。

Result:Eight compounds were elucidated as β amyrin palmitate, taraxastery acetate, luteolin 7 O α L rhamanopyranosyl (1→2)β D glucopyranoside,luteolin 7 O β D glucopyranoside, triacontanic acid,β sitosterol, stigmasterol and stigmast 7 en 3β ol.

结果 :从全草中分离得到 5个化合物,β香树脂醇棕榈酸酯,蒲公英醇乙酸酯,木樨草素 7 O α L 鼠李糖基(1→ 2 )β D 葡萄糖苷,木樨草素 7 O β D 葡萄糖苷,三十碳酸;1个混合物,β谷甾醇、豆甾醇、豆甾 7 烯 3β醇。

And the results indicate that the principal stress directions in study area are mainly NE-SW, and the second substage tectonic twist made the direction deflect from North to East, but the primary direction changed little; tectonic activities during the O〓~S~D stage is some violent, most of the area are under high stresses status, and rock fracture degree is correspondingly higher, as coinciding with the drill cores observation, i.

通过数值分析,模拟了塔中Ⅰ号断裂带和塔中45井三维模拟区O〓灰岩的构造应力场和应变场,结果表明:研究区主应力方向为北东~南西向,第二期的构造扭动使其由北向东发生了一定的偏转,但总的方位变化不大;O〓~S~D时期,塔中地区构造运动较强,研究区大部分处于高应力状态,岩石破裂程度较高,而岩芯观察结果也证实了这一结果,即O〓灰岩地层中早期形成的构造结构面比较发育,单个结构面的规模也较大;C~P时期,岩石的破坏程度较早期有所提高,主要表现在两个方面,一是各局部区岩石的破坏程度普遍有所提高;二是各个级别破裂区的分布范围相应地扩大了;研究区应力分布表现出明显的不均匀性,特别是剪应力,无论是O〓~S~D时期,还是C~P时期,都有很大的差异性,特别是在小断层的端部,剪应力比较集中,而且在断层的两盘,剪应力方向和大小都变化极快。

The crystal belongs to triclinic, space group P-1 with α=0.775 1(2) nm, b=0.837 7(2) nm, c=1.003 7(2) nm,α=75.57(3),β=83.05(3),γ=86.08(3), D=1.296 g/cm^3, Z=2, F(000)=256,μ=0.095 mm^(-1), and the final deviation factor R=0.0545 and wR=0.146 0. X-ray analysis reveals that molecules are linked by intermolecular O-H…O hydrogen bonds formed between the adjacent molecules.

具体测定结果如下:该晶体属于三料晶系,P-1空间群,α=0.7751 (2) nm, b=0.8377 (2) nm, c=1.0037 (2) nm,α=75.57 (3),β=83.05 (3),γ=86.08 (3), D=1.296 g/立方公分,Z=2, F(000)=256,μ=0.095 mm^(-1),最终偏差因子分别为R=0.0545,wR=0.1460.X-射线衍射分析表明,分子之间通过相邻分子间形成的O-H…O氢键相连。

Result: Seven phenolic compounds were identified as rosmarinic acid(1),gallic acid(2),gentisic acid 5-O-(6′-O-galloyl)-β-D-glucopyranoside(3),caffeic acid(4),p-coumaric acid(5),ethyl caffeate(6) and acteoside(7),respectively.

结果:分离得到7种酚类化合物,经结构鉴定为:迷迭香酸(1),没食子酸(2),龙胆酸5-O-(6′-O-没食子酰基)-β-D-吡喃葡萄糖苷(3),咖啡酸(4),对香豆酸(5),咖啡酸乙酯(6)和acteoside(7)。

RESULTS:12 compounds separated from Dendranthema nankingense were elucidated as cerotic acid,β-sitosterol,ursolic acid,chrysoeriol,luteolin,caffeic acid,daucosterol,chrysoeriol-7-O-glucoside,luteolin-7-O-glucoside,linarin,rutin and potassium nitrate.

结果:从菊花脑中分离得到12个化合物,即正二十六烷酸、β-谷甾醇、熊果酸、金圣草黄素、木犀草素、咖啡酸、胡萝卜苷、金圣草黄素-7-O--βD-葡萄糖苷、木犀草素-7-O--βD-葡萄糖苷、蒙花苷、芦丁、硝酸钾。

Process for the preparation of phosphatidylserine of formula wherein R and R independently represent a saturated, mono-unsaturated or polyunsaturated acyl C10-C30, X=OH or OM where M=alkaline or alkaline earth metal, ammonium, alkylammonium including the transphosphatidylation reaction between phosphatidylcholine of the general formula wherein R and R and X have the above specified meanings, R=CH2-CH2- NH2 o CH2-CH2-N(CH3)3 and Serine in D, L or racemic form catalysed by the phospholipase D enzyme, characterised in that said reaction is carried out in a hydroalcoholic medium containing an aliphatic alcohol and in the presence of bivalent metal oxide.

本发明涉及制备式CH 2 OR 1 CHOR 2 CH 2 O-P-OCH 2 -CH(NH 2 )-COOHX的磷脂酰丝氨酸的方法,其中R 1 和R 2 独立地表示饱和的、单不饱和的和/或多不饱和的酰基C 10 -C 30 ,X=OH或OM,其中M=碱或碱土金属、铵、烷基铵,该方法包括通式CH 2 OR 1 CHOR 2 CH 2 O-P-OR 3 X的磷脂酰胆碱其中R 1 和R 2 以及X具有上述特别的含义,R 3 =CH 2 -CH 2 -NH 2 或CH 2 -CH 2 -N (CH 3 3 与D、L或外消旋形式的丝氨酸之间的转磷脂酰化反应,该反应是通过磷脂酶D酶催化的,其特征在于所述的反应是在包含脂族醇的含水醇介质中并且在二价金属氧化物的存在下进行的。

Based on relative literatures,this part has included five resesearch aspects as below.1 Fifteen compounds were isolated and purified by extraction,column chromatography,and their structures were determined on the basis of spectral analysis: acteoside(Ⅰ-1),isoacteoside(Ⅰ-2),crenatoside(Ⅰ-3),cistanoside F(Ⅰ-4),sinapoyl-4-O-β-D-glucoside(Ⅰ-5),adenosine(Ⅰ-6),β-siterol(Ⅰ-7),oleanic acid(Ⅰ-8), succinic acid(Ⅰ-9),caffeic acid(Ⅰ-10),protocatechuic aldehyde(Ⅰ-11),p-hydro xybenzyl alcohol(Ⅰ-12),β-daucosterol(Ⅰ-13),D-galacitol(Ⅰ-14),D-mannitol(Ⅰ-15).Ⅰ-4~15 were obtained from this plant for the first time,andⅠ-6,7,9,and 13 were isolated from Orobanche genus for the first time.2 The scavenging test of DPPH showed that most compounds have comparative antioxidant activity as L-ascorbic acid and part of them show better activity such as the O.coerulescens extract and phenylethanoid glycosides.Acteoside showed potent free radical scavenging effects with a median inhibition concentration of 25.6μg/ml.3 The anti-HBV activities of acteoside,isoacteoside and crenatoside were measured,and all of them showed suppressive activity on the expression of HBsAg and HBeAg in the HepG2.2.15 cell line.

本论文在文献调研基础上对紫花列当化学成分及生物活性进行了研究,并从免疫抗病毒角度探讨紫花列当中特征性成分类叶升麻苷的肝保护作用及其机制。1采用大孔树脂、硅胶和Sephadex LH-20等色谱技术对紫花列当进行系统的植物化学研究,从中分离得到19个化合物,利用UV和NMR等波谱手段及理化性质鉴定了其中的15个化合物,分别为类叶升麻苷(Ⅰ-1)、异类叶升麻苷(Ⅰ-2)、crenatoside(Ⅰ-3)、cistanoside F(Ⅰ-4)、sinapoyl-4-O-β-D-glucoside(Ⅰ-5)、腺苷(Ⅰ-6)、β-谷甾醇(Ⅰ-7)、齐墩果酸(Ⅰ-8)、琥珀酸(Ⅰ-9)、咖啡酸(Ⅰ-10)、原儿茶醛(Ⅰ-11)、对羟甲基苯甲酸(Ⅰ-12)、β-胡萝卜苷(Ⅰ-13)、D-半乳糖醇(Ⅰ-14)和甘露醇(Ⅰ-15除化合物Ⅰ-1、Ⅰ-2和Ⅰ-3外,其余化合物均为首次从该植物中分离得到。2)通过大孔树脂富集该药材有效部位苯乙醇总苷,并采用HPLC测得其所含特征性成分类叶升麻苷的含量可达80%以上。3DPPH自由基清除试验显示紫花列当提取物及其所含的苯乙醇苷类化合物均具有较好的抗氧化能力,其清除DPPH自由基能力接近于抗坏血酸。4采用卡介苗整体致敏、脂多糖离体攻击构建大鼠原代肝细胞免疫性损伤模型,在体外观察类叶升麻苷的保肝作用。

In absence of above problems, aim for evidence-based target dose—spironolactone 50 mg o.d.

在没有上述问题时,旨在达到以证据为基础的目标剂量:安体舒通50 mg o.d,共或依普利酮50 mg o.d或最大的耐受剂量。

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I didn't watch TV last night, because it .

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