查询词典 D.A.

Finally, we deal with the stability problem of the Bergman kernel, i.e., do the Bergman kernels of D_k. converge to the Bergman kernel of D on compact subsets of D × D where D_k i-s a sequence of bounded domains converges to a bounded domain D in the sense of Boas?

最后我们研究Bergman核的稳定性问题，即，若一列有界域D_k按Boas意义下收敛于一个有界域D，是否有D_k的Bergman核在D×D上局部一致地收敛到D上的Bergman核？

To study the applicable prospect of suicide gene on tumor therapy in clinic,we cloned the gene of D-amino acid oxidase and the gene of yeast cytosine deaminase.We hope to establish the transgenic mices of DAAO gene and YCD gene,and the two transgenic strain mices are valuable animal system for studying the biological characteristic of DAAO gene and YCD gene ,for studing the killing activity of DAAO/D-Ala and YCD/5-FC gene therapy systems on tumor.The D-amino acid oxidase gene derived from R.gracilis and it could oxidize D-amino acids. Hydrogen peroxide(H2O2) is a reactive oxygen species generated in the deamination of D-Ala catalyzed by DAAO.

为了探讨自杀基因在临床肿瘤治疗中的应用前景，建立自杀基因肿瘤治疗评价的动物模型，我们克隆了D-氨基酸氧化酶(D-amino acid oxidase，DAAO)基因和酵母菌胞嘧啶脱氨酶(yeast cytosine deaminase，YCD)基因，希望建立DAAO基因及YCD基因转基因小鼠，为研究DAAO及YCD基因的生物学特性、开发和评价DAAO／D-Ala及YCD／5-FC自杀基因系统进行肿瘤治疗建立良好的实验动物模型。

Content of Chla,β-carotene and zeaxanthin of S. platensis grown in Se decreased, violaxathin, fucoxanthin, 19'-hexanoyloxyfucoxanthin and peridinin increased, Chla and Chlb of D. salina also decreased, but carotene increased, all pigments of D. zhanjiangensis increased except violaxanthin and 19'-hexanoyloxyfucoxanthin decreased. Effect of Ge on pigments of microalgaes were different in different algaes: Chla,β-carotene and zeaxanthin of S. platensis decreased, three other carotene increased, in D. salina, violaxanthin and lutein decreased, violaxathin, fucoxanthin and 19'-hexanoyloxyfucoxanthin increased, all pigments of D. zhanjiangensis increased except fucoxanthin and peridinin decreased; Chla,β-carotene and violaxanthin of Chlorella sp increased, but fucoxanthin and peridinin decreased.

暴露于硒中的钝顶螺旋藻（S.platensis）的叶绿素A、β-胡萝卜素和玉米黄素的含量都减少，岩藻黄素、19'-乙酰氧化岩藻黄素、多甲藻素和紫黄素的含量明显增加，盐生杜氏藻的叶绿素类也减少，但类胡萝卜素的含量则增加，湛江叉鞭金藻（D.zhanjiangensis）中除紫黄素和19'-乙酰氧化岩藻黄素有减少外，其它色素都增加；锗对四种微藻光合色素的影响也不尽相同，钝顶螺旋藻（S.platensis）的叶绿素A、β-胡萝卜素及玉米黄素含量减少，岩藻黄素、19'-乙酰氧化岩藻黄素和紫黄素的含量增加，盐生杜氏藻中除紫黄素和叶黄素有增加外，其它色素都减少，湛江又鞭金藻（D.zhanjiangensis）正相反，除岩藻黄素和多甲藻素有减少外，其它色素都增加，小球藻的叶绿素A、β-胡萝卜素和紫黄素增加较大，但岩藻黄素和多甲藻素则减少。

Results Compared to those before treatment the volume of the implanted keloid of Group D began to decrease since 14 days after treatment time-dependently (all P 《 0.05), and the volumes of the other 3 groups continued to increase and peaked on days 21, 14, or 7 respectively (all P 《 0.05).Microscopy showed infiltration of a larger quantity of histiocyte in the keloid tissue, and more obvious collagen disorganization and apoptosis of fibroblasts in Group D than in the other 3 groups.The protein expression of Bcl-2 was more remarkable and the protein expression of BAX was less remarkable in Group D than iu the other 3 groups.

结果 用药前和用药后7、14、21、28、35 d，D组瘢痕疙瘩组织块体积(mm3)分别为173±5、172±5、147±5、125±6、112±7和84±9，从用药后14 d开始明显缩小(均P＜0.05)；而其他3组瘢痕疙瘩组织块体积均明显增大，从用约后7 d开始各时点测得的体积均明显大于D组(均P＜0.05)。D组瘢痕疙瘩组织中有大量小鼠组织细胞浸润，胶原结构破坏和成纤维细胞凋亡明显重于其他3组，Bcl-2蛋门质表达明显弱于而Bax蛋白质表达明显强于其他3组。

In this paper,we discuss the extension of the Dω-order and D*ω-order in partiany or-dered group,obtain the necessary and sufficient condition for an extension of the partial-or-der in partially ordered group to Dω-order and D*ω-order, and the condition for the exten-sion of every partial order in a group to Dω-order.

讨论了偏序群的Dω－序扩展，得到了偏序群的偏序可扩展成为Dω－序的充要条件，以及每一偏序均可扩展成为Dω－序的条件，同时刻划了Dω－序群。

The rabbits were feeded by estradiol valerate everyday as follows. Group A: E〓V 1. 8mg/d, group B: E〓V 3. 6mg/d, group C: E〓V 7. 2mg/d, group D: E〓V 3. 6mg/d+MPA 3. 6mg/d, group E was the untreated control group, group F was the untreated sham control group.

之后给予口服雌激素或联合应用孕激素共16周，给药方案如下：A组〓V 1.8mg／天，B组〓V 3.6mg／天，C组〓V 7.2mg/天，D组〓V 3.6mg/天+MPA 3.6mg/天，E组和F组均不用药。

Results: Tyroserleutide can significantly increase the life span of H22 tumor-bearing mice by 50-70% in dosages of 20ug/kg/d-80ug/kg/d,specially the high dosage of 80ug/ml can significantly increase the life span by 69.24%; Tyroserleutide can inhibit the growth of transplanted hepatocellular tumor BEL-7402 in nude mice,the rate of tumor inhibition was25-50% in dosages of 40-320ug/ml ,the inhibition rate of 160ng/ml was 44.03%; Tyroserleutide could inhibit the growth of H22 and BEL-7402 tumor in a dose-dependent manner. Simultaneously, tumoricidal activity of tyroserleutide against BEL-7402 cell line in vitro was observed hinger when compared with the control group(P.05).The inhibition effect of 72hrs was higher than 24hrs,48hrs,96hrs.And specially the high dosage of 160ug/ml can significantly inhibit growth of tumor cell by 19.36%. Tyroserleutide can activated PEM and marked enhance cytotoxicity andphagocytosis functions in vitro and in vivo. The OD values of cytotoxicity were observed hinger when compared with the control group(P.05).The cytotoxicity of macrophages activated by tyroserleutide against BEL-7402 and B16-F10 was 35.58%,61.2% in vitro and21.39%,47.63% in vivo. The cytotoxicity rate of nude mice PEM was 32.86%,73.07% in vivo. Furthermore, tyroserleutide alone could stimulated the production of IL-1B TNF- a and NO by M . Tyroserleutide and LPS could synergistically activated M producing more cytotoxicity effectors. Conclusion: Tyroserleutide had inhibition functions against hepatoma carcinoma .Its possible mechanisms were related to the affect that Tyroserleutide could inhibit tumor cell directively and induce tumor cells apoptosis or death effectively.

结果：酪丝亮肽能显著延长腹水型肝癌H_(22)小鼠的生存时间，给药剂量为80μg／kg／d时疗效最显著，达到69.24％，在20μg／kg／d-80μg／kg／d剂量范围内生命延长率为50-70％，给药剂量与荷瘤鼠生存时间呈现一定量效关系；酪丝亮肽能显著抑制人肝癌BEL-7402移植瘤裸鼠的肿瘤生长，给药剂量为160μg／kg／d时疗效最显著，抑制率为44.03％，并且在40-320μg／kg／d剂量范围内抑制率为25-50％，给药剂量与肿瘤抑制率呈现一定量效关系；酪丝亮肽体外对人肝癌BEL-7402细胞生长有一定的抑制作用，在作用72hrs时各浓度酪丝亮肽对肿瘤细胞的抑制作用较24hrs、48hrs、96hrs明显，其中浓度为100μg／ml时抑制率达19.36％；酪丝亮肽体内外均能增强小鼠腹腔巨噬细胞对肿瘤细胞的杀伤：体外作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与效应细胞对照组相比有显著性差异(P＜0.05)杀伤率分别达到35.58％、61.2％；体内作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P 。05)，杀伤率分别达到21.39%、47.63%；裸鼠腹腔巨噬细胞经酪丝亮肤作用后对BEL一7402、B 16一F10杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P.05)，最高杀伤率分别达到32.86%、73.07%；酪丝亮肤能增强单核巨噬细胞系统的吞噬功能，吞噬指数与生理盐水组比较有显著性差异(P.05)；酪丝亮肤体外作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与效应细胞对照组相比有显著性差异(P.05)；酪丝亮肤体内作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与生理盐水对照组相比有显著性差异(P.05)；酪丝亮肤能促进鼠巨噬细胞株R戌W264.7分泌合成IL一1p和NO，IL一1日、NO水平分别在酪丝亮肤作用24hrs、12hrs时达到高峰，酪丝亮肤单独应用能提高巨噬细胞的分泌合成功能，而且酪丝亮肤能与LPS协同作用刺激巨噬细胞的细胞毒效应分子分泌合成。

Results: Different manifestations of skin infection, such as nodule, papule, ulcer and lesions mimicking molluscum contagiosum appeared 2-9 d after inoculation, with a mean of (3.42±1.17) d in immunocompromised group and (4.25±1.42) d in immunocompetent group.

结果：两组小鼠均于接种菌悬液后2~9 d［免疫抑制组(3.42±1.17)d、未抑制组(4.25±1.42)d］产生了结节、丘疹、溃疡、传染胜软疣样皮损，并均于接种后22~44 d［免疫抑制组(36.75±4.20)d、未抑制组(29.00±4.75)d］自愈。

The next Day after I came home to my Hutch with him, I began to consider where I should lodge him, and that I might do well for him, and yet be perfectly easy my self; I made a little Tent for him in the vacant Place between my two Fortifications, in the inside of the last, and in the outside of the first; and as there was a Door, or Entrance there into my Cave, I made a formal fram'd Door Case, and a Door to it of Boards, and set it up in the Passage, a little within the Entrance; and causing the Door to open on the inside, I barr'd it up in the Night, taking in my Ladders too; so that Friday could no way come at me in the inside of my innermost Wall, without making so much Noise in getting over, that it must needs waken me; for my first Wall had now a compleat Roof over it of long Poles, covering all my Tent, and leaning up to the side of the Hill, which was again laid cross with smaller Sticks instead of Laths, and then thatch'd over a great Thickness, with the Rice Straw, which was strong like Reeds; and at the Hole or Place which was left to go in or out by the Ladder, I had plac'd a kind of Trap-door, which if it had been attempted on the outside, would not have open'd at all, but would have fallen down, and made a great Noise; and as to Weapons, I took them all to my Side every Night.

&星期五&，这是我救他命的一天，这样取名是为了纪念这一天。我教他说&主人&，并告诉他这是我的名字。我还教他说&是&和&不是&，并告诉他这两个词的意思。我拿出一个瓦罐，盛了一些羊奶给他。我先喝给他看，并把面包浸在羊奶里吃给他看。然后，我给了他一块面包，叫他学我的样子吃。他马上照办了，并向我做手势，表示很好吃。

I have already describ'd my Habitation, which was a Tent under the Side of a Rock, surrounded with a strong Pale of Posts and Cables, but I might now rather call it a Wall, for I rais'd a kind of Wall up against it of Turfs, about two Foot thick on the Out-side, and after some time, I think it was a Year and Half, I rais'd Rafters from it leaning to the Rock, and thatch'd or cover'd it with Bows of Trees, and such things as I could get to keep out the Rain, which I found at some times of the Year very violent.

前面我已描述过自己的住所。那是一个搭在山岩下的帐篷，四周用木桩和缆索做成坚固的木栅环绕着。现在，我可以把木栅叫做围墙了，因为我在木栅外面用草皮堆成了一道两英尺来厚的墙，并在大约一年半的时间里，在围墙和岩壁之间搭了一些屋椽，上面盖些树枝或其他可以弄到的东西用来挡雨。因为，我发现，一年之中总有一段时间，大雨如注。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。