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NF-κB and ERβare directly binding together in Jurkat nucleus.E_2 may affect the transcriptive activity of NF-κB via ERβand further affect the fate of Jurkat cell.

ERβ与NF-κB在Jurkat细胞核中存在直接相互作用,E_2可能通过ERβ影响了NF-κB的转录活性,进一步影响了Jurkat细胞的命运。

Conclusions1、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

结论1、E_2可增加Jurkat细胞的凋亡,并增加Fas、FasL的蛋白表达,且其作用与E_2的剂量和处理时间呈正相关。2、Jurkat细胞上存在ERα、ERβ的表达,且E_2可上调这两种受体的表达,E_2剂量越大,ER表达量越高。3、E_2可能通过ERβ发挥其促进Jurkat细胞凋亡的作用。4、E_2能增加Jurkat细胞中NF-κB的转录活性,Jurkat细胞中NF-κB活性增加有促进凋亡的作用。

The invention relates to a pipeline polyurea outer anticorrosive coating and the making method thereof, making heated prepolymerization reaction on dibenzo-methane diisocyanate, carbodiimide diisocyanate, polyether binary alcohol and polyether trihydric alcohol to prepare prepolymer solution A, and making end amino polyethylene oxide ether, dimethyl sulfur-based toluene diamine, diethyl diamine, iso-propyl titanate solution, polyacrylate, carbon black, titanium dioxide and lightweight calcium carbonate into solution B, and as using, respectively heating the solutions A and B to 65 deg.C and then mixing them, then quickly spraying and curing to form a coat.

本发明涉及一种管道用聚脲外防腐涂料及制造方法,由二苯基甲烷二异氰酸酯、碳化二亚胺化二异氰酸酯、聚醚二元醇和聚醚三元醇通过加热预聚反应制成预聚物的A液、由端氨基聚氧化乙烯醚、二甲硫基甲苯二胺、二乙基甲苯二胺、钛酸异丙酯溶液、聚丙烯酸酯溶液、碳黑、钛白粉和轻质碳酸钙配制而成的B液组成,使用时将A液和B液分别加热至65℃后混合,然后快速喷涂固化形成涂层。

Methods Thirty adult New Zealand rabbits were divided into three groups, group A,B,C, with ten rabbits in each group. One full-thickness defects of articular cartilage, 4 mm×5 mm×2.5 mm in size, was made in the trochlear groove of the left femur of each rabbit. The defects of group A and B were filled with BMP/FG and FG respectively. The defects of group C were left empty.

30只新西兰种成年兔随机分为A,B,C三组,每只兔子左膝股骨髁间凹做一大小为4 mm×5 mm×2.5 mm的全层关节软骨缺损。A、B组缺损内分别填充BMP/FG及FG,C组为空白。

CD1a and CD83 molecules could also be expressed on the surface of CD3+ T lymphocytes and CD19+ B lymphocytes. The expression levels of CD1a and CD83 in activated lymphocytes were higher than those in the unactivated lymphocytes, and higher in B lymphocytes than in T lymphocytes.

结果该细胞表达特征性分子CD1a、CD40、CD80、CD83、CD86, CD1a 、CD83在CD3+T、CD19+B淋巴细胞上也表达,在激活的淋巴细胞上表达水平高于未激活的淋巴细胞,而且B淋巴细胞上的表达水平高于T淋巴细胞。

The chicks were divided into A and B experimental groups. Chicks in A group were occluded for 3 weeks,chicks in B group occluded for 2 weeks and then unoccluded for 1 week.

实验眼分为A、B两组,非遮盖眼作为对照组,其中实验A组来亨鸡眼持续遮盖3周,实验B组来亨鸡眼持续遮盖2周后去遮盖1周。

77Cm〓 are observed and predicted to be splitting of vibration mode of inter-icosahedral B-B bonds, which are unrelative to the atmospheric conditions.

IR结果发现所有样品在2850.27cm〓和2917.77cm〓处均有吸收峰,这是由于B〓O中的B〓二十面体位于菱面体单胞内,对称性降低,发生简并分裂所致。

Based on the genetic distance by SSR data, the cluster analysis with unweight pair-group method using arithemetic averages produced two major clusters that closely corresponded with the genome composition of the varieties (A genome, and B genome and their hybrids between A genome and B genome).

应用非加权类平均聚类方法,在相似系数0.61处将24个品种分为两大类群,类群Ⅰ是以A基因组为主的品种群,类群Ⅱ是以B基因组和A基因组与B基因组杂交的品种群。

ResultsCompared with group A and group C, significant increase in the levels of IL 8 and MDA and decrease in the activities of SOD and GSH Px were noted in group B (F=5.86-18.41,q=3.15-7.17, P.01); compared with group A, the activity of SOD and GSH Px was not changed markedly, the levels of IL 8 and MDA rised slightly but with no statistically significant. Mitochondria became vacuolated and deformed in group B, slightly swollen in group C.

结果 与A组、C组相比较,B组SOD、GSH Px的活性显著下降,MDA含量、IL 8浓度显著上升(F=5.86~18.41,q=3.15~7.17,P.01);与A组比较,C组SOD、GSH Px活性无明显变化,MDA含量及IL 8浓度轻微上升,但无统计学差异。B组肺组织线粒体破坏,呈空泡样变,C组仅见线粒体轻微肿胀。

All illustrate that NF-κB ASODN is effect to the rat endometriosis model, further verificate there is intimate relation between NF-κB and endometriosis.

说明用NF-κB反义寡核苷酸抑制治疗内异症模型有效,进一步证实NF-κB与内异症的发病机制有密切关系。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。