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Methods By a monoclonal antibody immobilization of platelet antigen assay, antiplatelet autoantibodies were detected using monoclonal antibodies specific for glycoproteins Ⅰb,Ⅱb/Ⅲa and P-selectin in patients with ITP and nonimmune thrombocytopenia. Meanwhile, RP% and PAIgG were measured in the same samples with flowcytometry.

通过改良的单克隆抗体特异性捕获血小板抗原试验测定ITP(86例)与非免疫性血小板减少(30例)患者血浆中血小板膜糖蛋白Ⅰb、GPⅡb-Ⅲa以及P-选择素自身抗体,同时以流式细胞术检测相应的RP%及PAIgG。

The results show that the most stable P5 is the doublet state of b isomer evolved from regular tetrahedron P4 while the most stable P(superscript + subscript 5) and P(superscript - subscript 5) are the singlet state of e, j isomers evolved from square P4, respectively.

结果表明,最稳定的P5为由正四面体的P4演变来的b结构的二重态,P(上标+下标 5)和P(上标-下标 5)则为由正方形P4演变来的e结构和j结构的单重态。

Treatment of N-p-tolylsulfonylindole 1 with acetyl chloride in dried dichloromethane gave the title compound, N-p-tolylsulfonyl-3-acetyl-indole 2 C17H15NO3S, M(subscript r=313.36 in 89% yield. Single-crystal structure of 2 was determined by X-ray crystallography.2 crystallizes in the triclinic system, space group P-1 with a=10.0264(13), b=12.5913(16), c=14.1621(18)?

N-对-甲苯磺酰-吲哚(1)在二氯甲烷中与乙酰基氯反应得到产率为89%的N-对-甲苯磺酰-3-乙酰基-吲哚(2)(分子式:C17H15NO3S,分子量:313.36),用单晶X-射线衍射方法测定了2的晶体结构并表明:属三斜晶系,空间群为P-1,单胞参数为a=10.0264(13),b=12.5913(16),c=14.1621(18)?

Objective To investigate the curative effect of left ventricular hypertrophy with uretic indapamide, Methods 96 patients wiht LVH were divided into two groups, 50 patients in A group were treated with indapamide 2,5~5mg/d, and 46 patients in B group with nifedipine 20~60mg/d for 12 months, Results Blood pressure、interventricular septum thickness、left ventricular posterior wall thickness、left ventricular mass index and left ventricular ejection fraction in all cases were improved after treatment, A group was better than B in LVEF, Conclusion Both indapamide and nifedipine can regress LVH, and improve left heart function

目的 观察新型噻嗪类利尿剂吲达帕胺逆转左心室肥厚的效果。方法 96例高血压LVH患者,分别给予吲达帕胺(A组,50例)2,5~5mg/d和硝苯地平控释片(B 组,46例)20~60mg/d持续12个月治疗,观察治疗前后血压及左室结构变化。结果两组治疗前后血压、室间隔厚度、左心室后壁厚度、心室重量指数和左心室射血分数均有改善(P<0,05~0,01),A组在改善LVEF方面优于B组(P<0,05)。结论吲达帕胺具有与硝苯地平类似的逆转LVH作用,有明显改善左心功能作用。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P<0.01),该变化与血中的浓度无关(P>0.05);②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000),而与小球TGF-β1阳性表达无关(P>0.05),尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P<0.01),还与小管间质TGF-β1阳性表达呈正相关(P<0.05):③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P<0.05),小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P<0.01),而小球TGF-β1阳性表达与肾组织损伤无关(P>0.05);④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P<0.01),与小球内细胞数呈负相关(P<0.05),该结果与其在组织中的表达一致;尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05);在轻度肾病理损伤时,尿'l'G卜pl、I卜6、Col一IV水平即升高,而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

For simplicity let us suppose that firm 1 has no monopsonistic power over any factors whose amount it can vary, so that supply curves of such factors are horizontal at prices of P'a, P'b,…, the prices that implicitly correspond to d'.

2为简化起见,假设厂商1对于生产要素(指它可以改变其使用量的任何生产要素)没有买方垄断权力,这样,这些要素的供给曲线,就是在d'点相应的价格P'a, P'b,…上的水平线。

ResultsCompared with group A and group C, significant increase in the levels of IL 8 and MDA and decrease in the activities of SOD and GSH Px were noted in group B (F=5.86-18.41,q=3.15-7.17, P.01); compared with group A, the activity of SOD and GSH Px was not changed markedly, the levels of IL 8 and MDA rised slightly but with no statistically significant. Mitochondria became vacuolated and deformed in group B, slightly swollen in group C.

结果 与A组、C组相比较,B组SOD、GSH Px的活性显著下降,MDA含量、IL 8浓度显著上升(F=5.86~18.41,q=3.15~7.17,P.01);与A组比较,C组SOD、GSH Px活性无明显变化,MDA含量及IL 8浓度轻微上升,但无统计学差异。B组肺组织线粒体破坏,呈空泡样变,C组仅见线粒体轻微肿胀。

Immunosuppressants include cyclosporine, azathioprine and prednisone. Results: After transplantation, release of waist pain was most obvious; occurrence rate of haematuria decreased from 83.3%to 12.5%(P.01); hypertention did not change in 1 month but improved in 1 year (P.01); polycystic kidney size examined by B-ultrasound showed no difference and stayed in "steady" state.

结果:移植术后腰部胀痛症状改善最为明显;术前频发肉眼血尿者为83.3%,术后减为12.5%,相差非常显著(P.01);高血压在术后1个月内改善不明显,而在术后1年时改善非常明显(P.01);多囊肾B超测定值,术前与术后各期相比,大小无显著差异,呈现&稳定&状态。

On the basis of ecologic balance, developing the complex biological preparation as a goal, we first explored two compatibly antagonists to control the leaf disease of forest plant and hoped this two antagonistic fungi could play a cooperative role in controlling the pine needle blight. The main research results were as follows: 1 , The dual test showed the two antagonistic fungi(Gliocladiutm virens ,Bacillus firmus)had some differences to Pestalotia funerea in the inhibition mode. The role of G virens to the P.funerea, mainly displayed the competition in the nutrition and space, but the B. firmus had the distinct inhibition zone to the P.

本研究以生态平衡为理论基础,开发复合生物制剂为目标,首次将两种亲和拮抗菌用于森林植物叶部病害,以期两种复合拮抗菌在松属植物赤枯病防治中发挥协同作用,其主要研究结果如下: 1、对峙培养显示两种颉抗菌(Gliocladium virens、Bacillus firmus)对赤枯病菌的抗生方式有一些差异。G.virens对P.funerea的作用,主要表现为营养与空间上的竞争,无抑菌圈;而B.firmus对P.funerea有明显的抑菌圈(平均6mm),对峙培养4-5d后菌丝逐稀疏、干枯、变黄。

F iber B ragg grat ing st rain senso rs w ere characterized and embedded into the p re2 st ressed concrete beam of HuL an river bridge. Embedding techniques and p ro tect ivemethods suitable fo r civil engineering w ere p resented. W ith FBG senso rs, internal st rains of the concrete beam w ere deter2 m ined during the st ressing p rocess.

采用与土木工程施工特点相适应的传感器安装工艺与保护方法,将光纤B ragg 光栅埋于正在建设的呼兰河大桥预应力箱梁中,测量了预应力张拉过程中混凝土结构内部的应变变化。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。