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Results Same conservative sites and key catalytic sites existed among SjLDH and LDHs from other species. Similarity of SjLDH compared to CsLDH, TvLDH and HsLDH was 75%, 17%, 58%-60% respectively. Phylogenetic analysis demonstrated that the evolution relation between SjLDH and DmLDH was closer than the relation between SjLDH and CeLDH, the relationship between SjLDH and HsLDH-B,-C was closer than HsLDH-A. Three trans-membrane regions were found, the region of 98aa-106aa in three hydrophilia regions located outside of membrane was inferred as the major antigen epitope. This antigen epitope had significant difference with LDHs from protozoon ( Pf ., Tg ., Tv .) and had 1-3 amino acid residue difference with MmLDH, HsLDH-A,-B,-C, and was the same with CsLDH. One of the key catalytic residues and substrate binding loop were located in this region. Tertiary structure demonstrated that 98aa-106aa was on the surface of the protein and formed a substrate binding loop, other two key catalytic sites were at the position near the loop.

结果 SjLDH与其他物种的同源序列含相同的保守位点及催化活性位点,与华支睾吸虫LDH同源性最高为75%,与阴道毛滴虫LDH同源性最低为17%,与人LDH(HsLDH-A,-B,-C)的同源性为58%~60%; SjLDH与果蝇的进化距离较秀丽隐杆线虫为近,3种人LDH中与HsLDH-B、-C的进化距离较HsLDH-A为近;该蛋白具有3个跨膜区域,3个高亲水性区域,主要的线性表位98aa~106aa位于膜外,与原虫LDH相同区域差异显著,而与其他LDH有1~3个氨基酸的差异,关键催化位点之一及底物丙酮酸结合区域位于该区域,蛋白质同源模建分析表明该区域位于蛋白表面形成环状结构,3个关键催化位点位于该区域或在其附近。

The mechanism of the interaction between bovine serum albumin and pyrano [4,3-b] pyran derivative, 2-amino-7-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydropyrano [4,3-b] pyran-3-carbonitrile, was studied by means of fluorescence spectroscopy under physiological conditions.

用荧光光谱法分析了在生理条件下一种吡喃并[4,3-b]吡喃衍生物-2-氨基-7-甲基-4-(4-硝基苯)-5-氧代-4H,5H-吡喃并[4,3-b]吡喃-3-腈与牛血清白蛋白的作用机制。

In chapter 4,poly(thieno[3,4-b]pyrazine),poly(6H-pyrrolo[3,4-b]pyrazine), poly(furo[3,4-b]pyrazine),and their oligomers are studied.

在第五节中,我们分析了几种聚噻吩并[3,4-b]吡嗪的衍生物以及它们的多聚物。

METHODS:After the treatment of TRAIL or LPS at different doses,we tested the nuclear translocation of NF-κB by cell immunohistochemical staining and electrophoretic mobility shift assay,and evaluated the level of IκB by RT-PCR under pyrrolidine dithiocarbamatetreatment.

当不同浓度的TRAIL和LPS作用于细胞后,我们通过细胞免疫组化染色和凝胶电泳迁移试验来检测NF-κB核转位的情况。并通过RT-PCR的方法粗略评定二硫代氨基甲酸吡咯烷对抑制蛋白IκB的影响。

But this does not mean that A and B are communicating; B just observes a random sequence of positive and negative signs.

然而,这并非意味着A与B之间在通信;B观测到的只是一个随机出现的无规正负符号的序列。

Objective To investigate the relationship among 3 GP Ⅱb and the funciton of GP Ⅱb T13959 G in the platelet transfusion refractoriness.

目的:研究血小板膜糖蛋白Ⅱb三种基因多态性之间的关系及CP Ⅱb, T13959 G在血小板输注耐受中的作用。

Without changes others crafted a and b files, you can append a and b are the connection between the related file.

在不改动他人制作的A和B文件的情况下,可以追加A和B相关文件间的连接信息。

We find that, i the diagrams withthe annihilation topology have a suppression factor 〓 relative to those withspectator topology; ii our results are much different from other model predic-tions for some decays modes; iii the pure W-exchange process 〓with a branching ratio 〓 can be found even before the B-factory era;iv for B →ππ,πK and KK decays, our results are well below the experimen-tal upper limits, but they are about one order of magnitude below the BSWpredictions.

其次,我们从有效哈米顿出发,利用微扰QCD方法系统研究了末态为两个赝标介子的B介子衰变过程,对可能的图进行了分类,给出了一般的计算方法和一般性公式,并且将其应用于纯W湮灭和W交换过程,B→ππ,πK和KK过程以及〓→PP过程。

The immune level tested in different time after injection with ginkgolic acids in sensitization mode showed that the expression of CD3〓 and CD4〓T lymphocytes increased, but CD8〓 was restrained, while the B lymphocytes was also increased. The results suggested that sensitivity was approved and T lymphocytes proliferation was induced, which strength cell immunity responsion, at the same time B lymphocytes was differentiated to IgE antibody-producing cells when contacted with ginkgolic acids as allergen.

大鼠经致敏方式接触银杏酸后,在不同时间的细胞免疫水平与体液免疫水平的研究结果表明,大鼠CD3〓及CD4〓T淋巴细胞的表达增加,而CD8〓T淋巴细胞的表达受到明显抑制,同时参与体液免疫的B淋巴细胞百分率呈增高趋势,提示银杏酸可能作为变应原使机体敏感性增强,诱导T细胞分裂增殖,增强细胞免疫应答,同时促进B细胞增殖分化成IgE抗体产生细胞。

Here there is no tariff revenue to be lost from tariff reduction, and the country gains the entire shaded areas a+b, composed of the increase in consumer surplus a and tariff revenue b.

这里没有关税收入将失去来自关税削减,国家取得整个阴影区+ b、沉稳的增加,消费者盈余关税收入b。

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推荐网络例句

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。