查询词典 AFP

Hepatoid variant of yolk sac tumor: Usually seen under 25 year old woman. You shoud search other areas to see if there is classic reticular pattern of YST. IHC can include AFP.

肝样卵黄囊瘤：经常发生于25岁以下的女性中，观察其他区域是否具有卵黄囊瘤典型的网状结构，免疫组化包括AFP。

The muta tion in P53 gene take part in the occurrence and development of HCC and it might associate directly with AFP. The P53 protein had important significance in the judgement of HCC prognosis.

P53基因的突变发生在肝癌启动阶段之后；P53基因突变与AFP关系密切；P53蛋白对判断肝癌预后有重要意义。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

There is at present still no prenatal blood test for BWS, however an elevated AFP level in a singleton pregnancy in the presence of an omphalocele should bring BWS into discussion.

目前仍然没有针对BWS的产前血液测试，然而怀孕期间的AFP水平升高和脐突出的出现应当考虑BWS的可能。

ZGF can effectively inhibite the expression of PCNA and AFP in rat hepatic precancerous lesion tissue, and ZGF has the function of lessening the paraplasm of rat hepatic precancerous lesion tissue.

大剂量正肝方能有效降低大鼠癌前病变肝组织PCNA和AFP的表达，减轻大鼠癌前病变肝组织的异常增生。

Methods Serumal CA153,CEA,AFP and CA125level of patients with malignant and benign mammary neoplasm was investigated respectively by electrochemoluˉminescence immunoassay.

采用电化学发光免疫分析法测定乳腺癌患者及乳腺良性疾病患者血清的CA153、CEA、AFP和CA125。

Injured liver tissue homogenate could induce the ex pressions of AFP and Alb in MSCs.

此方法可获得纯度较高MSCs，损伤肝组织匀浆可诱导MSCs表达AFP和Alb。

These results suggested that AFP can be used as a target gene of DNA vaccine in heptocellular carcinoma therapy.

成功构建了能在真核细胞中表达的重组质粒phAFP，为AFP DNA疫苗治疗肝癌的研究打下基础。

Methods The causes of death were judged synthetically according to the patients' history, liver function test,serum marker, AFP and image analysis including B type of ultrasound and CT.

根据患者的病史、肝功能实验、血清标志、AFP、B超、CT等影象学检查综合判断。

During IFN therapy, serum AFP levels significantly decreased, regardless of virologic response to treatment.

在干扰素治疗期间，血清AFP水平显著下降，不论是否对治疗产生病毒学应答。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。