查询词典 ADR

We define the ADR and the ADRcompensation in the theory research. The paper goes into detail about the ADR theory basis andthe responsibility constitution of other countries and provides the theory basis in order to make itclear why the victims should get the compensation and who should undertake the responsibility.(3)According to the analysis of the data statistical and the investigation, most reports come from themedical institutions while the reports from the production and operation enterprises are extremelyfew, only making up 1%. The speakers are mostly doctors. The serious ADR is about 2% andoccur at different ages. 50 -year-old middle-aged persons and old persons suffer from the ADReasily. In those reports, the ADR caused by using the one drug is about 90%; the ADR caused bythe anti-infection medicine ranks first due to using it wide in clinical medicine and applyingunreasonably. The intravenous injection easily causes the ADR.

对各国药品不良反应损害补偿的理论基础和责任构成进行阐述，为解决为什么要对药品不良反应受害者进行补偿、由谁承担责任提供了理论依据。3、我国药品不良反应现状研究方面，药品不良反应数据统计分析调查，发现报告主要来源于医疗机构，生产和经营企业报告数量极少，企业的报告数只占总数的1％，报告人都是以医生为主，严重不良反应发生的比例占药品不良反应报告总数的2％左右，不同年龄段都有药品不良反应发生，其中年龄大于50岁的中老年人发生的几率最大，在药品不良反应报告总数中，主要是使用一种药品的情形，占90％左右，抗感染药物占各类药物的首位，这与抗感染药物在临床广泛及不合理应用有关，静脉给药一直高居引起药品不良反应给药途径之首。

Methods］ MTT assay was employed to test the lethal concentration 50 (IC50) of sensitive germline (SK-OV-3) and ovarian cancer cell subline induced by ADR (SK-OV-3/adr) treated by 4 drugs, resistance index and reverse multiple were calculated. The changes of drug content were observed by fluorescence microscope, the intracellular accumulation of ADR was evaluated by fluorospectrophotometry, the changes of mdr 1/P-gp resistance were observed respectively by RT-PCR and Western blot.

方法］MTT法检测药物对敏感细胞株（SK-OV-3）和诱导的耐药细胞株（SK-OV-3/adr）的半数致死浓度（IC50），计算耐药指数和加逆转剂后的逆转倍数，荧光显微镜观察不同时间细胞内的药物含量变化，荧光分光光度法测定细胞内ADR的含量，RT-PCR和Western blot法检测细胞耐药前后mdr1/P-gp的变化。

Result The ADR of metoprolol was connected with interdicting β-receptor, and Clinical manifestations is familiar to Cardiovascular system ADR firstly, secondly, Respiratory system ADR and Allergic reactions.

结果美托洛尔致不良反应与其阻断β受体有关，临床表现以心血管系统不良反应最常见，呼吸系统不良反应、变态反应次之。

Objective: To analyze ADR distribution and the cost of treatment for ADR.

目的：分析ADR及由ADR导致的治疗费用。

Methods Using Wistar rats as animal pattem of ADR-induced myocardial injury and sodium selenite as protective agent.The double flourescent staining of apoptosis and expression of transforming growth factor β1 (TGF β1) were examined in liver tissue of animal pattern of ADR-injury by immunohistochemical and TUNEL,and the level of lipid peroxidation in serum was observed.

通过复制大鼠阿霉素性心肌损伤的动物模型，以亚硒酸钠作为保护因素，应用原位末端标记法和免疫组化技术检测大鼠肝细胞凋亡和肝细胞转化生长因子β1表达，并观察了大鼠血清中脂质过氧化含量。

Result: The reports tell us, it takes a higher incidence of ADR to female patients between 41～60 years old; ADR happens mainly to intravenously administrable especially for antineoplastic drug. The most clinical performances are the injuries accour to skin and its accessory; Secondly there are some injuries to the whole bodies as 5 serious examples.

结果：198例ADR中，以41～60岁年龄段患者发生率较高，男性高于女性；静脉给药是引发ADR的主要途径，与抗肿瘤药有关的ADR最为多见；临床表现以皮肤及其附件损害最常见；其次为全身性损害，其中较严重的6例。

It was one of the reason for renal tissue damage that the findings revealed the high level expression of CyP mRNA in ADR nephropathy, and reflected the grade or progress in ADR nephropathy.

说明阿霉素肾病肾组织高水平的环孢素亲合素基因表达是肾组织损伤的原因之一，对CyP 在自身免疫性疾病和器官移植排斥中的研究具有重要的理论与应用价值。

OBJECTIVE: To explore cervical adjacent zygapophyseal joint stress distribution following two level ADR and anterior cervical discectomy and fusion, so as to provide biomechanical reference for clinical application of two level ADR.

目的：观察轴向载荷对双节段颈椎人工椎间盘置换和前路椎间融合内固定对邻下位节段关节突关节内压力的影响，以期为双节段人工颈椎间盘置换的临床应用提供生物力学依据。

Department of orthopaedics, Xiangya Hospital, Central-south University, Changsha, China3 Objectives: To study cervical adjacent zygapophyseal joint stress distribution following two level ADR and ACDF on, in order to provide biomechanical reference for clinical application of two level ADR. Methods: Eleven healthy adult fresh-frozen multi-segmental cervical spine segments were utilized in this study and biomechanically evaluated under the following C4/5, C5/6 cervical disc conditions:⑴intact spine;⑵he Bryan Disc prosthesis implantation;⑶the intervertebral fusion.

取11具新鲜完整的成人下颈段标本，按实验先后分别制成C4/5、C5/6椎间盘完整、椎间盘置换、椎间融合三个模型组，在标本上施加轴向分级载荷，将微型阻电式压力传感器置入C5/6、C6/7关节突关节内，测量合组各分级载荷下C5/6、C6/7关节突关节内的压力。

RESULTS:Of the501ADR cases,226cases were resulted from antibiotic drugs which accounted for45.1%,80cases were resulted from by traditional Chinese drugs preparaˉtions which accounted for16.0%;ADR most commonly manifested itself in the injury of skin and appendants,which accounted for48.9%(245cases),then the damage of digestive system and circulation system,there were21(4.2%)comparative serious ADR cases among which;most cases were resulted from iv which accounted for65.9%(330cases)of the total.

现就患者年龄、给药途径、引起ADR的药物种类及涉及器官等方面进行总结，并简要分析如下。1资料与方法1 1资料来源收集我市各县、市2004年ADR报告共501例。

The network space is the typical form of abstract space when it comes to the digital stage.

网络空间是抽象空间数字化阶段的典型形式。

The Notarial System,as the system of judicial certification in our country,is both the constructor and the defender of social credit system,It has its special value and function in the social honesty.

公证制度作为我国司法证明制度，既是社会信用体系的建设者，同时也是社会信用的捍卫者，在诚信中有其特殊的价值和功能。