查询词典 ACH

The clinical application of PGD of ACH has accumulated experience for us to developing clinical PGD of other monogenic genetic conditions further.

ACH的临床PGD的实施，为我们进一步开展其它单基因遗传病的临床PGD积累了经验。

The decrease of iK,ACh by halothane may interfere with parasympathetic control of the heart.

氟烷可通过抑制iK，ACh，从而影响副交感神经对心脏的支配作用。

The decrease of IK,ACh by ethanol may impair parasympathetic control of the heart.

乙醇可抑制IK，ACh，从而影响副交感神经对心脏的调节作用。

After treatment with the above hormones, the rats were established anesthesia with urethan (1g/kg, i. p.); polyethylene catheters were inserted into the external jugular vein and the common carotid artery for drug administration, and then blood pressure was recorded. The arterial catheter was connected to a pressure transducer, and the blood pressure was displayed on the channel of BL-310 Experimental System of Biological Function through IBM computer. We assessed the changes of resting arterial blood pressure, the pressor responses of angiotensin Ⅱ(Ang Ⅱ, 0.01mg/kg), noradrenaline (NA, 0.01mg/kg) and adrenaline (Adr, 0.016mg/kg). The depressor responses of Ach (0.006mg/kg) and carotid sinus baroreflex were also discussed after treatment with the hormones in OVX rats.

用不同雌激素处理21天后，将动物用25％的氨基甲酸乙酯腹腔麻醉（1g／kg），做颈总动脉插管，通过压力换能器，将血压变化输入计算机，通过BL-310智能型生物信号显示与处理系统的压力测定模块，观察去势鼠及不同雌激素替代治疗大鼠静脉注射血管紧张素Ⅱ（AngⅡ，0.01mg／kg）、去甲肾上腺素（NA，0.01mg／kg）、肾上腺素（Adr，0.016mg／kg）的升压反应以及乙酰胆碱（Ach，0.006mg／kg）的降压反应和压力感受性反射的变化。

Objective The experiment studied the effects of acetylcholine and M-receptor agonist pilocarpine on the electric activities of the pain-related neurons in the locus ceruleus of normal rats,in order to further study the role and the interaction of ACh and LC in the modulation in the algetic sense.

目的 本实验观察大鼠侧脑室内加入外源性乙酰胆碱后，蓝斑核（Locus ceruleus，LC）痛反应神经元的电变化，以及M受体激动剂毛果芸香碱的激动效应，进一步研究ACh和LC在痛觉调制中的作用及其相互关系。

Methods The constriction induced by norepinephine (NE, 10-8-10-4 mol/ L) and diastole induced by acetylcholine (Ach, 10-8 -10-4 mol/ L) in thoracic aortic ring with angiosteosis induced by vitamin D3 plus nicotine in rats were recorded by BL-Newcentrary multichannel physiologic recorder.

维生素D3(VitD3)和尼古丁诱导大鼠血管钙化模型，通过BL-Newcentrary型多导生理记录仪，观察钙化大鼠离体胸主动脉环对去甲肾上腺素(norepinephine，NE)(10-8～10-4mol/L)和乙酰胆碱(acetylcholine，ACh)(10-8～10-4mol/L)引起的收缩和舒张反应。

The results show that ACh may have excitatory effects on the electric activity of the Pf neurons by M-receptor.

这些结果提示，在Pf神经元的活动中，ACh可以直接作用于M受体发挥其兴奋作用。

Hundreds of these esicles discharge their Ach onto a specialized area of postsynaptic membrane on the fiber.

数以百计的小泡释放Ach到达肌纤维突触后膜上专门的区域。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后，血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少，Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少，血小板聚集程度及红细胞聚集指数显著上升，病理切片显示胸主动脉内皮细胞破坏明显，脑心肾组织内的血管进一步增厚甚至几乎阻塞，导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR，脑体重比显著升高；心肌内出现明显的缺血梗塞疤痕灶，心体重比显著升高；肾小球明显萎缩、玻璃样变性，肾小管也变性甚至坏死，使肾硬化程度显著增加呈颗粒性固缩肾，肾体重比也显著减少。

Acclimatization 1.73±1.82** 0.61±0.06 0.98** P＜0.01 vs normoxic rats.After the aorta preparations were precontracted with NE at the concentration of 0.62 μmol/L, a ccumulative vasodilative effects of ACh were tested.

与常氧对照组相比，急性低氧和间断低氧习服后，大鼠主动脉对ACh各浓度(10- 9～10-5 mol/L)引起的舒张反应显著减弱(P＜0.01)，其最大舒张分别为常氧对照组的87.3％和79.7％，其EC50值分别为1.34和1.73 μmol/L，分别为常氧对照组EC50值0.20 μmol/L的6.7和8.6倍(表2)。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。