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These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明，缺血前20 min腹腔注射给药，然后缺血30 min，发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍， DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍)，而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍， DNA结合活性从3.1倍增为5.1倍)。

Primary culture of bovine corneal endothelial cells and whole rabbit corneas were used as the experimental materials. We first treated the cultured bovine corneal endothelial cells with PTPs inhibitor, sodium orthovanadate, with a variety of concentrations (25,50,100μM) for various durations (8,24 hrs). The effects of PTP inhibition on cellular distribution of cell-cell junctional proteins, such as N-cadherin, alpha-catenin and p120, were evaluated by immunohistochemical staining with fluorescein microscopy and confocal microscopy. Immunohistochemical staining with Ki67 Ab, a marker of cell proliferation, was also used to detect cells entering cell cycle.

实验材料为初代培养之牛角膜内皮细胞和全厚度之兔子眼角膜，使用sodium orthovanadate作为酪胺酸磷酸脢的抑制剂，接著以不同SOV浓度(25， 50， 100μM)及不同时间(8， 24 hrs)来处理初代培养之细胞与新鲜的兔子眼角膜，之后进行萤光染色并使用萤光显微镜及共轭焦显微镜进行影像撷取，以观察位於细胞与细胞间的蛋白质，例如：N-cadherin， alpha-catenin 和p120的改变，另外也使用Ki67抗体来侦测是否有进入cell cycle的细胞。

Fourteen unreported N-substituted piperidin-4-one oxime ethers derivatives were synthesized withsubstituted benzylamines or phenethylamine as raw materials via a series of Michael addition, Dieckmann condensation, hydrolysis decarboxylation reactions, oximation a...

以取代苄胺或苯乙胺为起始原料，依次经Michael加成，Dieckmann缩合，水解脱羧，肟化和醚化等多步反应合成了14个未见文献报道的N-取代哌啶酮肟醚衍生物。

Tamarense was studied. 5 mg·L~-1 of N-phenyl-2-naphthylamine was showed to have 50% inhibitory rate on A. tamarense after 3 days. 70 μL·L~-1 of linoleic acid appeared 40% inhibition rate on A. tamarense.70 μL·L~-1 of pelargonic acid had 85% inhibition rate at the 3 rd day with some increase in cell density later on.

结果表明，浓度高于5 mg·L-1以上的N-苯基-2-萘胺，3 d后能保持对塔玛亚历山大藻抑制率超过50%；浓度为70μL·L-1的亚油酸对塔玛亚历山大藻的抑制率约为40%；浓度为70 μL·L-1的壬酸第3天可以达到85%的抑藻率，但随后藻密度有反弹。

PhyA is the photoreceptor of far-red light perception in Arabidopsis and mediates the inhibition of the hypocotyl elongation under FR light. phyA has two domains : the N-terminal photosensory domain with a chromophore-binding site and the C-terminal domain which contains signaling motifs such as a kinase domain.

phyA为阿拉伯芥中远红光的接受体，在远红光中可抑制下胚轴延长，phyA的N端带有一个可感受光讯息的色基，C端含有可传递讯息给下游基因的kinase区域。

The monthly variations in Sr/Ca ratio of the Porites coral from Eastern Hainan Island have been studied using the ICP-AES technique.On the basis of the correlation analysis between Sr/Ca values and SST values measured from the Meteorological Station,a thermometer has been set up as a formula of SST=170-16,n=133,r=0.80,p=0.01,which is similar to the formula of SST=169-16.7 for Xisha waters.

文章采用全谱直读等离子体原子发射光谱的方法测定了1986~1996年海南岛东部海域滨珊瑚的Sr/Ca比值，建立了该海域月分辨率的Sr/Ca海水表面温度计方程：SST=170-16，n=133，r=0.80，p=0.01，此与韦刚健等在西沙海域建立的温度计方程：SST=169-16.7一致，这表明南海中、北部海域也出现有相似的微量元素温度计。

For the above purposes, using a tailored cyanometalate precursor,(1) Tp=hydrotris (pyrazolyl borate; Bu〓N〓=tetrabutylammonium cation , two trinulear complexes,〓(2),〓(3; cyclam: 1, 4, 8, 11-tetraazacyclotetradecane), two one-dimensional polymers,〓(4; dien: diethylenetriamine),〓(5), and a cluster 〓(6) have been synthesized and characterized structurally and magnetically.

基于上述研究热点，我们以修饰的氰基金属化合物(1)为构筑基元（Tp：三吡唑基氢硼烷，Bu〓N〓：四丁基铵离子），合成了两个杂三核化合物，〓(2)，〓（3；cyclam：1，4，8，11-四氮环十四烷），两个一维聚合物，〓（4；dien：二乙烯三胺），〓(5)，和一个十四核簇合物〓(6)。

A new compound,3-_6-{4-(4-vinylene)pyridyl} stilbenyl}-N-ethylcarbazole was synthesized,and characterized by elemental analysis,IR,MS and ~(1)H NMR spectra.

报道一种新型的D-π-D-π-A结构的化合物：3-(4-溴苯乙烯基)-6-[(4-乙烯基吡啶)苯乙烯基]-N-乙基咔唑的合成。

Learning depends on the capacity for ♀ n to remain integrated and yet lose rigidity.1 This is the foundation of the state of mind of the individual who can retain his knowledge and experience and yet be prepared to reconstrue past experiences in a manner that enables him to be receptive of a new idea.

Bion ，1962， p93学习要靠♀ n 保持其整合融摄的能力，而同时并不僵化，在这个基础上，心灵才可以真正地保有知识和体验，同时可以从既往的体验中重组建构，让个体能够接受新的观念。

In our work, as a preliminary experiment, the N-phenacylisoquinolinium bromide was reacted with methlhydrazine in refluxed acetic acid. Unexpectedly, 2-methyl-1,2,3-triazole was obtained. The further study of this reaction led to a more simple starting material,α-bromoacetophenone to react with methylhydrazine, obtaining the same product.

我们在研究N-苯乙酰异喹啉溴化物与甲肼在冰醋酸中的反应时，意外地得到了2-甲基-4-苯基-1，2，3-三氮唑，经过进一步的研究发现α-溴代苯乙酮与甲肼也能得到同样的产物。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新